All Reactions

2,481 adverse reaction types in FDA reports

#	Reaction	Reports	Deaths	Death Rate
1	Vomiting (334)	174,348	7,526	4.3%
2	Lethargy (see also Central nervous system depression in 'Neurological') (1018)	92,802	8,822	9.5%
3	Emesis (335)	69,317	953	1.4%
4	Diarrhoea (302)	64,292	4,150	6.5%
5	Lack of efficacy (ectoparasite) - flea (2649)	59,231	179	0.3%
6	Lack of efficacy - NOS (1039)	54,525	3,336	6.1%
7	Lack of efficacy (endoparasite) - heartworm (2430)	52,770	262	0.5%
8	Lack of efficacy (endoparasite) - hookworm (2798)	42,123	108	0.3%
9	INEFFECTIVE, HEARTWORM LARVAE (99115)	40,443	324	0.8%
10	Anorexia (996)	33,907	6,093	18.0%
11	Seizure NOS (645)	33,361	4,899	14.7%
12	Death (984)	29,452	29,293	99.5%
13	UNPALATABLE (99951)	27,321	137	0.5%
14	Behavioural disorder NOS (116)	24,337	2,025	8.3%
15	Digestive tract disorder NOS (305)	22,748	678	3.0%
16	Ataxia (654)	21,626	2,812	13.0%
17	Other abnormal test result NOS (1221)	21,162	3,575	16.9%
18	Death by euthanasia (981)	21,034	20,878	99.3%
19	Not eating (1207)	21,007	3,236	15.4%
20	Emesis (multiple) (2082)	19,150	999	5.2%
21	Weight loss (1043)	19,144	3,437	18.0%
22	Decreased appetite (998)	17,831	2,057	11.5%
23	Pruritus (960)	17,227	221	1.3%
24	Lack of efficacy (ectoparasite) - tick NOS (2658)	16,245	146	0.9%
25	Tablets, Abnormal (99026)	16,188	11	0.1%
26	Elevated alanine aminotransferase (ALT) (2050)	15,967	2,677	16.8%
27	Panting (855)	15,046	1,579	10.5%
28	Overdose (3036)	14,237	599	4.2%
29	Lack of efficacy (endoparasite) - roundworm NOS (2656)	13,930	43	0.3%
30	INEFFECTIVE, ASCARIDS NOS (99088)	13,787	37	0.3%
31	Depression (1024)	13,060	2,144	16.4%
32	INEFFECTIVE, HOOKS (99112)	13,039	38	0.3%
33	Containers, Damaged (99005)	13,017	0	0.0%
34	Accidental exposure (99809)	12,968	341	2.6%
35	Shaking (2002)	12,949	818	6.3%
36	Lack of efficacy (bacteria) - Borrelia (2784)	12,011	73	0.6%
37	Cardiac disorder NOS (202)	11,531	729	6.3%
38	Vocalisation (129)	11,363	1,824	16.1%
39	Elevated serum alkaline phosphatase (SAP) (2055)	11,291	2,127	18.8%
40	Fever (1032)	11,181	1,701	15.2%
41	Underdose (3037)	10,973	518	4.7%
42	Itching (958)	10,740	84	0.8%
43	Hypersalivation (293)	10,540	886	8.4%
44	Product problem (2283)	10,340	32	0.3%
45	Uncoded sign (1216)	10,179	219	2.2%
46	Elevated blood urea nitrogen (BUN) (2047)	10,167	3,012	29.6%
47	Bloody diarrhoea (315)	10,014	1,083	10.8%
48	Polydipsia (543)	9,574	1,114	11.6%
49	Inappetence (999)	9,069	1,086	12.0%
50	Lack of efficacy (bacteria) - NOS (2648)	8,915	1,558	17.5%
51	Facial swelling (see also 'Skin') (517)	8,541	117	1.4%
52	Loose stool (304)	8,484	513	6.0%
53	Product Defect, General (99021)	8,459	63	0.7%
54	Hives (see also 'Skin') (1525)	8,336	59	0.7%
55	Lack of efficacy (flea) (2649)	8,320	13	0.2%
56	Lack of efficacy (endoparasite) - tapeworm (2657)	8,280	32	0.4%
57	Application site hair loss (3)	8,127	49	0.6%
58	Color, Abnormal (99003)	8,087	19	0.2%
59	Tremor (1852)	8,033	577	7.2%
60	Drooling (292)	7,886	767	9.7%
61	Polyuria (718)	7,747	757	9.8%
62	Dehydration (1208)	7,651	2,025	26.5%
63	Elevated creatinine (2048)	7,526	2,228	29.6%
64	Hyperactivity (118)	7,434	199	2.7%
65	Abnormal radiograph finding (2070)	7,375	2,257	30.6%
66	Anaemia NOS (142)	7,342	2,445	33.3%
67	Leucocytosis NOS (163)	7,339	2,229	30.4%
68	Containers, Leaking (99961)	7,289	2	0.0%
69	Trembling (687)	7,230	523	7.2%
70	Scratching (959)	7,139	75	1.1%
71	Lack of efficacy (endoparasite) - whipworm (2801)	7,126	74	1.0%
72	Underfilling, Package (99030)	6,969	0	0.0%
73	Application site alopecia (2)	6,932	73	1.1%
74	Weakness (1023)	6,854	1,909	27.9%
75	Cough (884)	6,845	951	13.9%
76	Pain NOS (1012)	6,477	1,130	17.4%
77	Restlessness (119)	6,467	511	7.9%
78	Underfilling, Container (99959)	6,364	2	0.0%
79	Anaphylaxis (512)	6,311	971	15.4%
80	Weight gain (1050)	6,282	235	3.7%
81	Pale mucous membrane (222)	6,258	1,755	28.0%
82	Not drinking (541)	6,221	1,069	17.2%
83	Hyperglycaemia (1946)	6,174	1,322	21.4%
84	Lack of efficacy (tick) (2658)	6,102	71	1.2%
85	Twitching (686)	5,831	517	8.9%
86	Elevated liver enzymes (1942)	5,735	1,082	18.9%
87	Inappropriate urination (124)	5,684	735	12.9%
88	Agitation (121)	5,667	305	5.4%
89	Anxiety (115)	5,617	353	6.3%
90	Neutrophilia (168)	5,573	1,542	27.7%
91	Injection site swelling (91)	5,505	297	5.4%
92	Elevated total bilirubin (2052)	5,424	1,742	32.1%
93	Disorientation (660)	5,405	704	13.0%
94	Skin disorders NOS (1756)	5,186	144	2.8%
95	Medication error NOS (2282)	5,117	267	5.2%
96	Hiding (2207)	4,988	499	10.0%
97	Abnormal ultrasound finding (2069)	4,860	1,484	30.5%
98	Deafness (365)	4,836	113	2.3%
99	Appearance, Abnormal (99036)	4,824	15	0.3%
100	Underfilling, Tubes (99031)	4,808	1	0.0%
101	Walking difficulty (1902)	4,808	1,031	21.4%
102	Urinary incontinence (735)	4,683	728	15.5%
103	Tachycardia (192)	4,645	1,083	23.3%
104	Urinary tract infection (2026)	4,609	559	12.1%
105	Falling (651)	4,570	722	15.8%
106	Hyperphosphataemia (2046)	4,554	1,736	38.1%
107	Erythema (for urticaria see Immune SOC) (948)	4,509	137	3.0%
108	Nausea (1638)	4,502	333	7.4%
109	Intentional misuse (3039)	4,443	333	7.5%
110	Drug administration error (99819)	4,419	197	4.5%
111	Skin lesion NOS (966)	4,336	282	6.5%
112	Thrombocytopenia (160)	4,205	1,374	32.7%
113	Malaise (1027)	4,165	779	18.7%
114	Reluctant to move (1025)	4,123	785	19.0%
115	Reddening of the skin (946)	4,123	91	2.2%
116	Hypoglycaemia (1947)	4,092	1,045	25.5%
117	Lack of efficacy (protozoa) - Coccidia (2803)	4,076	242	5.9%
118	Aggression (113)	3,979	327	8.2%
119	Injection site pain (93)	3,968	190	4.8%
120	Drug dose omission (99825)	3,948	30	0.8%
121	Lameness (615)	3,919	677	17.3%
122	Proteinuria (1961)	3,907	684	17.5%
123	Lack of efficacy (bacteria) - Anaplasma (2990)	3,861	24	0.6%
124	Adipsia (542)	3,830	752	19.6%
125	Odor, Abnormal (99018)	3,829	27	0.7%
126	INEFFECTIVE, LOSS OF EFFECT (99125)	3,709	89	2.4%
127	Unable to stand (653)	3,706	1,052	28.4%
128	Limb weakness (1121)	3,668	655	17.9%
129	Foaming at the mouth (1074)	3,606	405	11.2%
130	Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') (1001)	3,581	1,116	31.2%
131	Tubes, Leaking (99029)	3,509	2	0.1%
132	Hypoalbuminaemia (1883)	3,488	1,118	32.1%
133	Convulsion (642)	3,461	728	21.0%
134	Dilated pupils (1414)	3,461	408	11.8%
135	Lateral recumbency (1135)	3,455	1,365	39.5%
136	Closure, Abnormal (99811)	3,450	3	0.1%
137	Lack of efficacy (endoparasite) - NOS (2436)	3,444	73	2.1%
138	Suspension, Abnormal (99024)	3,433	11	0.3%
139	Musculoskeletal disorder NOS (1120)	3,348	707	21.1%
140	Drug dose administration interval too long (99823)	3,322	43	1.3%
141	Dyspnoea (839)	3,279	1,428	43.5%
142	Difficulty of Use (99955)	3,272	5	0.2%
143	Appetite loss (997)	3,271	355	10.9%
144	Partial lack of efficacy (2001)	3,270	101	3.1%
145	Hair loss NOS (1507)	3,225	99	3.1%
146	Not himself/herself (2753)	3,198	426	13.3%
147	Decreased urine concentration (1963)	3,183	442	13.9%
148	Hyperkalaemia (1944)	3,176	650	20.5%
149	Recumbency (658)	3,154	1,436	45.5%
150	INEFFECTIVE, GLYCEMIC CONTROL (99110)	3,106	203	6.5%
151	INEFFECTIVE, ATOPY CONTROL (99090)	3,094	27	0.9%
152	Ketosis (567)	3,077	246	8.0%
153	Abdominal pain (263)	3,075	764	24.8%
154	No sign (93157)	3,058	97	3.2%
155	Seal, Abnormal (99022)	3,049	0	0.0%
156	Elevated gamma-glutamyl transferase (GGT) (2238)	3,047	631	20.7%
157	Tachypnoea (854)	3,011	794	26.4%
158	Leucopenia NOS (164)	2,998	591	19.7%
159	Hard, clumping (99953)	2,964	2	0.1%
160	Lack of efficacy (bacteria) - Ehrlichia (2805)	2,922	24	0.8%
161	Drug dose administration interval too short (99824)	2,892	40	1.4%
162	Skin scab (2179)	2,891	85	2.9%
163	Vials, Leaking (99035)	2,887	0	0.0%
164	Unclassifiable adverse event (2190)	2,876	234	8.1%
165	Neurological signs NOS (630)	2,859	686	24.0%
166	Pacing (2208)	2,836	286	10.1%
167	Lack of efficacy (roundworm) (2656)	2,765	13	0.5%
168	Blood in vomit (343)	2,751	519	18.9%
169	Device Defective NOS (93019)	2,733	28	1.0%
170	Hypothermia (1015)	2,724	1,131	41.5%
171	Urticaria (521)	2,718	33	1.2%
172	Lymphopenia (166)	2,716	622	22.9%
173	Pancreatitis (1891)	2,707	576	21.3%
174	Elevated serum alkaline phosphatase (ALP) (2055)	2,701	523	19.4%
175	INEFFECTIVE, HEARTWORM ADULTS (99114)	2,694	11	0.4%
176	Monocytosis (2420)	2,694	766	28.4%
177	Abnormal posture NOS (1132)	2,693	299	11.1%
178	Eye disorder NOS (for photophobia see 'neurological') (452)	2,682	301	11.2%
179	Bradycardia (188)	2,681	574	21.4%
180	Application site scab (15)	2,645	23	0.9%
181	Breathing difficulty (1170)	2,640	932	35.3%
182	Haematuria (1967)	2,626	534	20.3%
183	Laboured breathing (1171)	2,623	962	36.7%
184	Dermatitis (932)	2,569	179	7.0%
185	Blindness (406)	2,558	622	24.3%
186	Application site erythema (5)	2,556	28	1.1%
187	Limping (1990)	2,549	260	10.2%
188	Systemic disorder NOS (1052)	2,540	512	20.2%
189	Licking (1997)	2,506	65	2.6%
190	Vials, Damaged (99034)	2,500	0	0.0%
191	Elevated aspartate aminotransferase (AST) (2049)	2,499	493	19.7%
192	Nystagmus (691)	2,489	409	16.4%
193	Head tremor (1900)	2,485	144	5.8%
194	Collapse (see also 'Cardio-vascular' and 'Systemic disorders') (668)	2,438	871	35.7%
195	Elevated temperature (1033)	2,434	290	11.9%
196	Abnormal breathing (837)	2,381	609	25.6%
197	Neutropenia (167)	2,374	409	17.2%
198	Dispenser, Abnormal (99010)	2,350	2	0.1%
199	Rash (939)	2,339	44	1.9%
200	Heart murmur (213)	2,328	530	22.8%
201	Blood in faeces (1081)	2,312	255	11.0%
202	Muscle tremor (684)	2,279	227	10.0%
203	Containers, Abnormal (99004)	2,277	1	0.0%
204	Anaphylactoid reaction (1113)	2,272	100	4.4%
205	Confusion (659)	2,259	334	14.8%
206	Stumbling gait (657)	2,252	329	14.6%
207	Low platelet count (161)	2,247	605	26.9%
208	Caps, Abnormal (99002)	2,242	2	0.1%
209	Renal failure (720)	2,240	1,266	56.5%
210	Elevated globulins (2556)	2,235	503	22.5%
211	Hypoproteinaemia (1976)	2,220	710	32.0%
212	Gagging (344)	2,208	219	9.9%
213	Ear infection NOS (1435)	2,187	93	4.3%
214	Lack of efficacy (ectoparasite) - NOS (2492)	2,183	8	0.4%
215	Solution, Abnormal (99023)	2,181	13	0.6%
216	Injection site lump (92)	2,181	39	1.8%
217	Inappropriate defecation (123)	2,169	280	12.9%
218	Elevated amylase (2232)	2,124	625	29.4%
219	Retching (345)	2,121	179	8.4%
220	Application site reddening (1332)	2,120	16	0.8%
221	Hind limb paresis (1153)	2,118	515	24.3%
222	General illness (2071)	2,106	550	26.1%
223	Elevated cholesterol (total) (2266)	2,100	381	18.1%
224	Drinking a lot (545)	2,091	292	14.0%
225	Constipation (267)	2,044	317	15.5%
226	Pica NOS (134)	2,039	103	5.1%
227	Urine abnormalities NOS (1959)	2,026	336	16.6%
228	Ocular discharge (468)	2,022	260	12.9%
229	Application site pruritus (25)	2,009	16	0.8%
230	INEFFECTIVE, WHIPS (99158)	2,007	6	0.3%
231	Abnormal cytology (2588)	2,004	238	11.9%
232	Cardiac arrest (195)	2,003	1,672	83.5%
233	Hind limb ataxia (1134)	1,999	267	13.4%
234	Mydriasis (690)	1,997	258	12.9%
235	Elevated lipase (2168)	1,984	465	23.4%
236	Hypokalaemia (2418)	1,980	568	28.7%
237	Circling - neurological disorder (see also 'Behavioural disorders') (652)	1,965	497	25.3%
238	Elevated symmetrical dimethylarginine (SDMA) (2583)	1,964	373	19.0%
239	Blood in urine (1956)	1,952	357	18.3%
240	Icterus (499)	1,950	834	42.8%
241	Elevated renal parameters (1992)	1,945	616	31.7%
242	Facial oedema (1110)	1,927	89	4.6%
243	Product defect, product difficult to use/handle (see also 'Drug device difficult to use/handle') (99955)	1,919	7	0.4%
244	Application site irritation (24)	1,918	14	0.7%
245	Product label issues (99857)	1,916	15	0.8%
246	Proprioception deficit (1157)	1,865	443	23.8%
247	Decreased activity (2039)	1,855	182	9.8%
248	Head tilt - ear disorder (374)	1,848	199	10.8%
249	Localised pain NOS (see other 'SOCs' for specific pain) (1026)	1,833	237	12.9%
250	Stiffness NOS (1794)	1,827	244	13.4%
251	Hypochloraemia (2578)	1,824	523	28.7%
252	Hyponatremia (2512)	1,822	566	31.1%
253	Decreased packed cell volume (PCV) (2215)	1,814	580	32.0%
254	Alopecia (1309)	1,797	83	4.6%
255	Sneezing (873)	1,770	151	8.5%
256	Neoplasia NOS (1928)	1,770	898	50.7%
257	Distension of abdomen (312)	1,754	608	34.7%
258	Crying (130)	1,751	225	12.8%
259	Uncomfortable (2499)	1,733	220	12.7%
260	Localised hair loss (1581)	1,712	48	2.8%
261	Loss of hearing (1591)	1,707	54	3.2%
262	Unresponsive to stimuli (2247)	1,696	597	35.2%
263	Application site lesion (14)	1,693	25	1.5%
264	Renal disorder NOS (719)	1,684	694	41.2%
265	Mucous stool (1080)	1,681	103	6.1%
266	Hypotension (228)	1,676	505	30.1%
267	Sleepiness - systemic disorder (2529)	1,665	125	7.5%
268	Nasal discharge (871)	1,662	406	24.4%
269	Increased heart rate (193)	1,651	251	15.2%
270	Crust (1189)	1,615	107	6.6%
271	Unsteady gait (1858)	1,607	190	11.8%
272	Skin sore (962)	1,606	88	5.5%
273	Hot spot (pyotraumatic dermatitis) (1200)	1,604	43	2.7%
274	Hyperproteinaemia (2155)	1,597	395	24.7%
275	Azotaemia (2182)	1,557	555	35.6%
276	Hyperthermia (1014)	1,557	255	16.4%
277	Generalised itching (1492)	1,555	9	0.6%
278	Arthritis (569)	1,535	267	17.4%
279	Increased respiratory rate (856)	1,534	390	25.4%
280	Contamination, Foreign Object (99946)	1,531	0	0.0%
281	Staring (2635)	1,531	197	12.9%
282	Thrombocytosis (2116)	1,529	249	16.3%
283	Allergic reaction (1304)	1,528	46	3.0%
284	Head shake - ear disorder (375)	1,512	46	3.0%
285	Gait abnormality (1989)	1,512	209	13.8%
286	Unable to rise (2045)	1,488	560	37.6%
287	Bacterial skin infection NOS (1338)	1,484	109	7.3%
288	Unable to walk (3017)	1,484	582	39.2%
289	Vestibular disorder NOS (373)	1,471	207	14.1%
290	Head bobbing (2022)	1,461	108	7.4%
291	Tiredness (1844)	1,456	113	7.8%
292	Immune mediated haemolytic anaemia (1896)	1,455	531	36.5%
293	Frequent urination (733)	1,445	127	8.8%
294	Sedation (111)	1,426	164	11.5%
295	Swelling NOS (1214)	1,423	156	11.0%
296	Excessive licking and/or grooming (1974)	1,417	46	3.2%
297	Hypercalcaemia (553)	1,415	343	24.2%
298	Administration error NOS (3035)	1,414	53	3.7%
299	Staggering (655)	1,413	240	17.0%
300	Shivering (1905)	1,413	125	8.8%
301	Self trauma (125)	1,400	28	2.0%
302	Tarry or black stool (see also haemorrhagic diarrhoea) (318)	1,396	348	24.9%
303	Wobbliness (2871)	1,396	212	15.2%
304	Decreased red blood cell count (2157)	1,394	426	30.6%
305	Glucosuria (1960)	1,391	230	16.5%
306	Incorrect dose administered NOS (99833)	1,382	55	4.0%
307	Pyoderma (961)	1,368	86	6.3%
308	Alopecia local (900)	1,365	49	3.6%
309	Cyanosis (1009)	1,338	645	48.2%
310	Alopecia NOS (1310)	1,335	46	3.4%
311	Liver disorder NOS (1943)	1,335	551	41.3%
312	INEFFECTIVE, COCCIDIA (99093)	1,334	86	6.4%
313	Glazed eye (1211)	1,333	117	8.8%
314	Underfilling, Bottles (99038)	1,333	0	0.0%
315	Precipitate, Sediment (99962)	1,327	7	0.5%
316	Hypertension (224)	1,324	236	17.8%
317	Local swelling (not application site) (1580)	1,316	162	12.3%
318	Listless (1022)	1,309	196	15.0%
319	Otitis externa (356)	1,289	96	7.4%
320	Bruising (1360)	1,288	333	25.9%
321	Defect Unknown/Not Specified (99009)	1,284	33	2.6%
322	Application site inflammation (13)	1,270	10	0.8%
323	NT - Abnormal necropsy finding NOS (2142)	1,268	1,260	99.4%
324	Stomach upset (1800)	1,266	53	4.2%
325	Incorrect route of drug administration (99837)	1,264	82	6.5%
326	Respiratory distress (840)	1,259	750	59.6%
327	Tense abdomen (1978)	1,256	278	22.1%
328	Decreased drinking (2500)	1,250	164	13.1%
329	Sudden death (982)	1,241	1,238	99.8%
330	Flatulence (269)	1,238	65	5.3%
331	Drug administered at inappropriate site (99816)	1,237	18	1.5%
332	Medication error (2282)	1,235	48	3.9%
333	Pneumonia (842)	1,230	649	52.8%
334	INEFFECTIVE, SEDATION (99145)	1,229	80	6.5%
335	Polypnoea (857)	1,224	174	14.2%
336	Dry mucous membrane (1210)	1,224	277	22.6%
337	Hypersensitivity reaction (2241)	1,224	18	1.5%
338	Skin lump (1191)	1,212	128	10.6%
339	Not sleeping (140)	1,198	81	6.8%
340	Hind limb paralysis (2025)	1,193	451	37.8%
341	Bone and joint disorder NOS (577)	1,189	200	16.8%
342	Eosinophilia (162)	1,183	137	11.6%
343	Melaena (317)	1,182	372	31.5%
344	Musculoskeletal pain (2021)	1,177	165	14.0%
345	Tubes, Abnormal (99027)	1,170	0	0.0%
346	Febrile (1034)	1,164	220	18.9%
347	Allergy NOS (1307)	1,155	25	2.2%
348	Head tilt - neurological disorder (see also Head tilt - ear disorder) (2523)	1,153	201	17.4%
349	Head shake - behavioural disorder (2412)	1,152	46	4.0%
350	Excessive thirst (544)	1,144	168	14.7%
351	Cardiac enlargement (204)	1,140	452	39.6%
352	Hypothyroidism (404)	1,137	170	15.0%
353	Regurgitation (1888)	1,136	194	17.1%
354	Tubes, Damaged (99028)	1,136	1	0.1%
355	Low sodium-potassium ratio (Na:K ratio) (2630)	1,134	163	14.4%
356	Anaphylactic-type reaction (1114)	1,132	154	13.6%
357	Injection site abscess (72)	1,131	58	5.1%
358	Lack of efficacy (ectoparasite) - lice (2651)	1,127	6	0.5%
359	Discomfort NOS (2498)	1,126	126	11.2%
360	Inappropriate schedule of drug administration (99832)	1,115	23	2.1%
361	Lymphocytosis (165)	1,114	261	23.4%
362	Sleepiness - neurological disorder (127)	1,112	83	7.5%
363	Balance problem (372)	1,111	115	10.4%
364	Application site scratching (26)	1,110	7	0.6%
365	Dermal mass (2262)	1,109	92	8.3%
366	Faecal incontinence (1069)	1,107	258	23.3%
367	Electrolyte disorder (2144)	1,105	264	23.9%
368	Flaking skin (1474)	1,102	34	3.1%
369	Skin irritation (1760)	1,098	25	2.3%
370	Dry skin (1998)	1,091	25	2.3%
371	Ear discharge (349)	1,088	53	4.9%
372	Malodour (908)	1,083	76	7.0%
373	Abnormal stool colouration (1981)	1,082	157	14.5%
374	Hyperaesthesia (706)	1,073	95	8.9%
375	CULTURE/TITER DATA ABNORMAL (99241)	1,061	441	41.6%
376	INEFFECTIVE, ANTIINFLAMMATORY (99086)	1,059	90	8.5%
377	Corneal ulcer (415)	1,054	104	9.9%
378	Elevated creatine-kinase (CK) (2245)	1,053	235	22.3%
379	Discoloured urine (1964)	1,051	256	24.4%
380	Eye redness (457)	1,050	41	3.9%
381	Licking at application site (1973)	1,049	12	1.1%
382	Wound (2593)	1,048	90	8.6%
383	Partial deafness (367)	1,041	18	1.7%
384	Decreased haematocrit (2853)	1,039	275	26.5%
385	INEFFECTIVE, CUSHINGS (99095)	1,037	69	6.7%
386	INEFFECTIVE, ANESTHESIA (99082)	1,034	79	7.6%
387	General hair loss (1490)	1,032	33	3.2%
388	Product syringe issue (99860)	1,017	3	0.3%
389	Paddling (1226)	1,009	162	16.1%
390	Pulmonary oedema (848)	1,009	695	68.9%
391	Decreased haemoglobin (2214)	1,007	271	26.9%
392	Itchy skin (1145)	1,005	8	0.8%
393	Lack of efficacy (heartworm) (2430)	1,001	10	1.0%
394	Abnormal menace reflex test (1096)	993	235	23.7%
395	Skin inflammation NOS (1759)	993	33	3.3%
396	Eosinopenia (2862)	991	272	27.4%
397	Lack of efficacy (tapeworm) (2657)	990	2	0.2%
398	Stopper, abnormal (93005)	984	0	0.0%
399	Increased percentage reticulocytes (2213)	983	256	26.0%
400	Jaundice (501)	980	413	42.1%
401	Abnormal movement NOS (1131)	978	170	17.4%
402	Rubbing (2496)	969	14	1.4%
403	Apnoea (830)	967	521	53.9%
404	Necropsy performed (2142)	967	957	99.0%
405	Impaired vision (407)	963	149	15.5%
406	Eye irritation (453)	955	13	1.4%
407	Abnormal pupil light reflex (1097)	953	219	23.0%
408	Haematochezia (1982)	948	172	18.1%
409	Respiratory tract disorder NOS (1180)	945	460	48.7%
410	Urinary tract disorder NOS (739)	943	131	13.9%
411	Grand mal seizure (2727)	942	159	16.9%
412	Drug administration duration too long (99817)	938	32	3.4%
413	Lymphoma (176)	935	407	43.5%
414	High pancreatic-specific lipase (2692)	934	151	16.2%
415	Lymphadenopathy (174)	928	251	27.0%
416	Lip licking (2096)	928	29	3.1%
417	Hyperalbuminaemia (2154)	927	144	15.5%
418	Reduced responses (1021)	924	233	25.2%
419	Knuckling (578)	923	239	25.9%
420	Abnormal adrenocorticotropic hormone (ACTH) stimulation test (2663)	920	65	7.1%
421	Arrhythmia (186)	918	226	24.6%
422	Application site burn (2063)	911	10	1.1%
423	Lying down (2743)	908	171	18.8%
424	Star-gazing (2246)	904	40	4.4%
425	Application site reaction NOS (29)	897	13	1.4%
426	Biting -aggression (see also 'Skin and appendages disorders') (112)	896	98	10.9%
427	INEFFECTIVE, WORMS NOS (99160)	893	55	6.2%
428	Pulmonary disorder NOS (844)	893	450	50.4%
429	Elevated liver enzymes NOS (1942)	887	200	22.5%
430	Gall bladder & bile duct disorder NOS (480)	883	293	33.2%
431	Incoordination (1901)	882	123	13.9%
432	Intestinal disorder NOS (2440)	881	233	26.4%
433	Closure, Missing (99812)	878	0	0.0%
434	Wheezing (836)	876	151	17.2%
435	Injection site reaction NOS (100)	875	35	4.0%
436	Gastroenteritis (313)	865	89	10.3%
437	Swelling around eye (461)	864	24	2.8%
438	Heavy breathing (2776)	863	192	22.2%
439	Peritonitis (253)	859	503	58.6%
440	Muscle weakness NOS (1629)	858	184	21.4%
441	Conjunctivitis (469)	857	81	9.5%
442	Muscle wasting (611)	853	247	29.0%
443	Ascites (1030)	851	436	51.2%
444	Hypernatremia (2511)	851	233	27.4%
445	Lack of efficacy (ectoparasite) - ear mite (2791)	848	3	0.4%
446	Injection site inflammation (84)	847	57	6.7%
447	Bilirubinuria (2175)	838	224	26.7%
448	Skin hyperaemia (949)	837	28	3.3%
449	Pinnal erythema (1095)	837	20	2.4%
450	Hepatomegaly (494)	827	333	40.3%
451	Squinting (2235)	826	29	3.5%
452	Abdominal discomfort (2010)	825	125	15.2%
453	Increased appetite (1530)	825	56	6.8%
454	Decreased bowel movements (1939)	821	144	17.5%
455	Neurological symptoms NOS (1648)	813	181	22.3%
456	Open mouth breathing (1172)	812	202	24.9%
457	Distress (114)	809	142	17.6%
458	Haemorrhage NOS (177)	808	427	52.8%
459	Polyphagia (137)	806	46	5.7%
460	Skin ulcer (1194)	805	77	9.6%
461	Third eyelid protrusion (1105)	803	95	11.8%
462	Application site itching (23)	795	5	0.6%
463	Haematemesis (342)	785	151	19.2%
464	Eyes rolling back (2084)	785	49	6.2%
465	Stiffness limb (1793)	782	103	13.2%
466	Injection site bleeding (83)	780	66	8.5%
467	Diabetes (387)	777	157	20.2%
468	Skin and tissue infection NOS (1755)	777	68	8.8%
469	Hepatopathy (496)	774	249	32.2%
470	Hair shedding (1971)	774	21	2.7%
471	PR-LIVER, LESION(S) (99629)	772	631	81.7%
472	Diabetes mellitus (389)	770	118	15.3%
473	Quiet (2645)	770	122	15.8%
474	Crystalluria (2028)	769	80	10.4%
475	Hypoadrenocorticism (383)	768	56	7.3%
476	Application site swelling (20)	764	7	0.9%
477	Hypophosphataemia (2242)	764	157	20.5%
478	Swollen eye (1810)	763	43	5.6%
479	INEFFECTIVE, GASTRIC ULCER(S) (99109)	762	7	0.9%
480	Colic (264)	762	136	17.8%
481	Decreased body temperature (1016)	760	250	32.9%
482	Pancreatitis NOS (1891)	760	175	23.0%
483	General pain (see other SOCs for specific pain) (1011)	758	125	16.5%
484	Shock (220)	757	336	44.4%
485	Immune mediated thrombocytopenia (2009)	749	192	25.6%
486	Dullness (126)	739	250	33.8%
487	Chewing - pruritus (see also 'Oral cavity disorders') (2618)	735	13	1.8%
488	Contamination, Particulate Matter (99846)	731	3	0.4%
489	Application site pain (22)	729	11	1.5%
490	Generalised weakness (1496)	729	249	34.2%
491	Swollen limb (2402)	729	149	20.4%
492	Anisocoria (670)	726	128	17.6%
493	Intestinal perforation (1082)	726	395	54.4%
494	Otitis NOS (1984)	726	45	6.2%
495	Muscle shaking (1745)	726	54	7.4%
496	Elevated bile acids (2051)	725	71	9.8%
497	Trauma NOS (1932)	725	167	23.0%
498	Mental impairment NOS (1612)	725	186	25.7%
499	Balance impaired (1341)	725	85	11.7%
500	Fluid in abdomen NOS (2011)	724	388	53.6%
501	Solution/Suspension, crystals (93008)	722	3	0.4%
502	Application site skin change NOS (2200)	720	0	0.0%
503	Underfilling, Vials (99032)	719	0	0.0%
504	Ketonuria (2910)	719	147	20.4%
505	Localised itching (1582)	718	6	0.8%
506	Vomiting bile (2758)	715	92	12.9%
507	Elevated triglyceride (2508)	711	101	14.2%
508	Application site hair change (1878)	709	4	0.6%
509	Excessive chewing, licking and/or grooming (1974)	704	13	1.8%
510	Tremor of limb (1853)	704	47	6.7%
511	Injection site necrosis (89)	703	71	10.1%
512	Epistaxis (864)	699	243	34.8%
513	Pustules (938)	699	35	5.0%
514	Unable to jump (2394)	699	77	11.0%
515	Pleural effusion (1184)	695	439	63.2%
516	Skin slough (943)	695	90	12.9%
517	Expired drug administered (99830)	695	34	4.9%
518	Unwell (2883)	694	176	25.4%
519	Warm feeling to the touch (2742)	693	46	6.6%
520	Dysphoria (2531)	693	50	7.2%
521	Moist dermatitis (937)	692	42	6.1%
522	Increased packed cell volume (PCV) (2419)	691	127	18.4%
523	Reduced globulins (2557)	690	163	23.6%
524	Splenomegaly (185)	689	244	35.4%
525	Non-regenerative anaemia (145)	687	181	26.3%
526	PR-SKIN, LESION(S) (99673)	682	93	13.6%
527	Other ear disorder NOS (1667)	675	35	5.2%
528	Respiratory arrest (831)	673	516	76.7%
529	Involuntary defecation (270)	673	117	17.4%
530	Unrelated death (2110)	673	662	98.4%
531	Sedation prolonged (1903)	670	59	8.8%
532	Lack of efficacy (protozoa) - NOS (2655)	670	61	9.1%
533	Urine leakage (2127)	668	73	10.9%
534	Disoriented state (1418)	666	90	13.5%
535	Difficulty to rise (2726)	665	146	22.0%
536	Haemorrhagic diarrhoea (314)	661	116	17.5%
537	Low thyroxine (T4) (2670)	653	120	18.4%
538	Dull (2274)	652	187	28.7%
539	Tongue disorder NOS (1845)	649	122	18.8%
540	Liver failure (1109)	648	410	63.3%
541	Temporary deafness (2455)	647	6	0.9%
542	Patient instructions for use on label confusing (93081)	647	2	0.3%
543	Difficulty standing (2868)	645	163	25.3%
544	Hyperpigmentation (913)	644	22	3.4%
545	Pinnal reddening (360)	644	9	1.4%
546	Acute renal failure (1159)	643	288	44.8%
547	Urinary bladder disorder NOS (732)	641	167	26.1%
548	Stupor (1019)	640	185	28.9%
549	Pyrexia (1031)	640	95	14.8%
550	Pyuria (2255)	640	102	15.9%
551	Partial anorexia (2591)	638	102	16.0%
552	Hair coat discolouration (1187)	637	19	3.0%
553	Circulatory collapse (see also 'Neurological' and 'Systemic disorders') (223)	636	161	25.3%
554	Weak pulse (2187)	635	261	41.1%
555	Abdominal mass (2277)	633	365	57.7%
556	Vials, Abnormal (99033)	632	0	0.0%
557	Diabetic ketoacidosis (2053)	631	265	42.0%
558	Muscle spasm NOS (682)	628	52	8.3%
559	Low blood pressure (229)	624	188	30.1%
560	Labelled drug-drug interaction medication error (99842)	622	82	13.2%
561	Increased salivation (1533)	622	68	10.9%
562	Head tilt - neurological disorder (2523)	621	95	15.3%
563	Cataract (444)	619	74	12.0%
564	Red eye (1721)	619	40	6.5%
565	Enlarged liver (495)	617	229	37.1%
566	Hypocalcaemic condition (560)	613	248	40.5%
567	Periorbital oedema (460)	610	26	4.3%
568	Found dead (983)	610	609	99.8%
569	Palpable mass NOS (2000)	609	140	23.0%
570	Colitis (265)	608	120	19.7%
571	Lack of efficacy (protozoa) - Giardia (2806)	606	2	0.3%
572	Joint swelling (568)	605	95	15.7%
573	Soft stool (3069)	601	33	5.5%
574	High blood pressure (225)	599	78	13.0%
575	Hair change (1506)	598	25	4.2%
576	Neurological disorder NOS (2728)	597	169	28.3%
577	Enlarged lymph node (localised) (2405)	594	118	19.9%
578	INEFFECTIVE, ANTIBIOTIC (99083)	594	155	26.1%
579	Tooth disorder (1846)	592	67	11.3%
580	Biting - pruritus (see also 'Behavioural disorders') (2608)	591	10	1.7%
581	Not urinating (2520)	587	136	23.2%
582	Immediate pain upon injection (2410)	586	23	3.9%
583	Oedema of the extremities (see also other SOCs for most applicable oedema) (518)	585	158	27.0%
584	Recovery prolonged (1904)	585	94	16.1%
585	Bottles, Damaged (99039)	581	0	0.0%
586	Dental disease (2227)	579	79	13.6%
587	Muscle stiffness (609)	578	99	17.1%
588	Localised rash (1584)	578	8	1.4%
589	Adrenal gland disorder NOS (378)	578	183	31.7%
590	Straining to defecate (2453)	574	79	13.8%
591	Hyperexcitation (122)	571	42	7.4%
592	Pulmonary congestion (843)	571	393	68.8%
593	Head down (2397)	571	115	20.1%
594	Joint pain (588)	566	70	12.4%
595	Oral bleeding (297)	566	251	44.3%
596	Regenerative anaemia (1056)	566	168	29.7%
597	Mass NOS (2886)	566	148	26.1%
598	Syringe, Abnormal (99025)	561	0	0.0%
599	Whining (2756)	561	53	9.4%
600	Impaired consciousness (1217)	558	112	20.1%
601	Anal sac disorder (1999)	558	43	7.7%
602	Drunken gait (1133)	558	56	10.0%
603	Horizontal nystagmus (1143)	553	86	15.6%
604	Gastric ulcer (340)	551	193	35.0%
605	Sleep disturbance NOS (141)	551	48	8.7%
606	Pallor (1215)	550	185	33.6%
607	Unexplained death (985)	550	543	98.7%
608	Increased borborygmus (2091)	550	16	2.9%
609	Fly biting behaviour (2469)	550	32	5.8%
610	Low blood urea nitrogen (BUN) (2700)	549	132	24.0%
611	Horner's syndrome (702)	548	45	8.2%
612	Excoriation (1198)	546	24	4.4%
613	Urination (1161)	541	94	17.4%
614	Prolonged capillary refill time (1937)	541	161	29.8%
615	PR-LUNG(S), LESION(S) (99631)	539	527	97.8%
616	Localised oedema (not application site) (1586)	536	104	19.4%
617	Application site bleeding (12)	536	12	2.2%
618	Facial paralysis (1144)	535	48	9.0%
619	Abdominal cavity disorder NOS (251)	535	245	45.8%
620	Injection site bruising (79)	533	43	8.1%
621	High sodium-potassium ratio (Na:K ratio) (2629)	532	51	9.6%
622	Loss of consciousness (667)	530	169	31.9%
623	Application site crust (16)	530	6	1.1%
624	Rectal bleeding (272)	529	174	32.9%
625	Oedema NOS (see other SOCs for specific oedemas) (1029)	529	169	31.9%
626	Lot # and /or Expiration date missing (99843)	528	2	0.4%
627	Barking (132)	527	42	8.0%
628	Rolling (2391)	525	53	10.1%
629	INEFFECTIVE, ANTIEMETIC (99085)	524	58	11.1%
630	Collapse of leg (1389)	524	106	20.2%
631	Hyposthenuria (2475)	523	44	8.4%
632	Papilloma (920)	521	11	2.1%
633	Hypocortisolaemia (2625)	521	24	4.6%
634	Contamination NOS (99008)	519	7	1.3%
635	Bumping into walls (2403)	518	114	22.0%
636	Muscle atrophy (see also Muscle wasting) (2470)	516	127	24.6%
637	Injection site oedema (90)	514	59	11.5%
638	Paresis (698)	511	151	29.5%
639	Swollen lip (see also 'Skin') (1817)	511	6	1.2%
640	Limb non-weight bearing (2768)	508	82	16.1%
641	Injection site lesion (86)	506	25	4.9%
642	Application site ulcer (35)	503	9	1.8%
643	Device breakage/fracture (93033)	503	13	2.6%
644	Application site stickiness (2750)	502	0	0.0%
645	Pancreas disorder (330)	501	257	51.3%
646	Blepharospasm (423)	500	23	4.6%
647	Product syringe missing (99861)	498	0	0.0%
648	Bloated (1349)	497	178	35.8%
649	Gingival hyperplasia (1886)	493	15	3.0%
650	Sickness (1748)	491	97	19.8%
651	Application site residue (2191)	490	8	1.6%
652	Stiff gait (1950)	489	94	19.2%
653	Septicaemia (1035)	487	364	74.7%
654	Limpness (2252)	487	113	23.2%
655	Respiratory signs (1181)	481	220	45.7%
656	Hypocalcaemia (2685)	481	192	39.9%
657	Proprioception abnormality (1155)	480	100	20.8%
658	Abdominal effusion (2164)	478	270	56.5%
659	Oral cavity disorder NOS (2229)	478	78	16.3%
660	Abscess NOS (2074)	474	125	26.4%
661	Apprehension (1055)	473	22	4.7%
662	Paralysis (696)	473	230	48.6%
663	Heart failure (197)	472	282	59.7%
664	Welt (1875)	472	14	3.0%
665	Papule (953)	469	10	2.1%
666	Haemorrhagic gastroenteritis (316)	468	85	18.2%
667	Appetite disorder NOS (1323)	468	55	11.8%
668	Missing Labels (99017)	466	1	0.2%
669	Alkaline urine (1952)	465	50	10.8%
670	INEFFECTIVE, WORMS (99160)	465	19	4.1%
671	Ear pain (347)	465	13	2.8%
672	Hepatitis (493)	463	161	34.8%
673	Red blood cell disorder (181)	463	110	23.8%
674	Swollen vulva (825)	460	36	7.8%
675	Halitosis (291)	458	69	15.1%
676	Lack of response to owner (2510)	454	58	12.8%
677	Injection site alopecia (73)	452	13	2.9%
678	Fungal skin infection NOS (1484)	452	24	5.3%
679	Low creatinine (2701)	451	111	24.6%
680	Eyelid oedema (1100)	450	17	3.8%
681	Lack of efficacy (lice) (2651)	450	0	0.0%
682	Temporary blindness (1829)	449	33	7.3%
683	PR-KIDNEY(S), LESION(S) (99627)	449	435	96.9%
684	Loss of bowel control (1070)	449	112	24.9%
685	INEFFECTIVE, EUTHANASIA (99105)	448	428	95.5%
686	Application site greasy fur (2057)	448	1	0.2%
687	Arched back (2275)	448	66	14.7%
688	Gastritis (341)	447	116	26.0%
689	Gastric perforation (1941)	445	239	53.7%
690	Keratoconjunctivitis sicca (471)	439	38	8.7%
691	Congestive heart failure (2429)	435	227	52.2%
692	Tongue protrusion (1078)	434	88	20.3%
693	Dermal cyst(s) (929)	433	32	7.4%
694	Erythematous rash (1449)	432	13	3.0%
695	Food refusal (2401)	431	51	11.8%
696	External ear disorder NOS (354)	430	33	7.7%
697	Ecchymosis (2038)	430	145	33.7%
698	Dental calculus (2226)	426	63	14.8%
699	Swollen face (see also 'Skin') (1811)	426	17	4.0%
700	Ulceration NOS (1038)	425	101	23.8%
701	Shallow breathing (2481)	425	113	26.6%
702	Lip oedema (see also 'Skin') (1577)	425	11	2.6%
703	Decreased heart rate (189)	424	83	19.6%
704	Anuria (712)	423	193	45.6%
705	Decreased percentage of reticulocytes (2212)	423	90	21.3%
706	Respiratory tract infection NOS (1182)	422	85	20.1%
707	Intervertebral disc disease (2579)	420	102	24.3%
708	Decreased cholesterol (total) (2265)	418	116	27.8%
709	Scooting (2224)	415	7	1.7%
710	Urinary retention (737)	414	72	17.4%
711	Incorrect storage of drug (99838)	414	15	3.6%
712	Allergic dermatitis (1303)	414	12	2.9%
713	Spasm (681)	413	86	20.8%
714	Coagulopathy (1057)	412	191	46.4%
715	Rigidity (1730)	410	57	13.9%
716	Enteritis (327)	408	208	51.0%
717	Injection site erythema (77)	407	16	3.9%
718	Injection site scab (85)	406	6	1.5%
719	Product defect NOS (2283)	406	8	2.0%
720	Oral ulceration (301)	405	78	19.3%
721	Loss of vision (1596)	405	94	23.2%
722	Swollen lymph node (1818)	404	92	22.8%
723	Focal seizure (2770)	404	38	9.4%
724	Somnolence (110)	402	39	9.7%
725	Drooping eyelid (2236)	402	35	8.7%
726	Increased red blood cell count (2613)	401	73	18.2%
727	Skin warmth (2398)	400	11	2.8%
728	Spleen and reticulo-endothelial system disorder NOS (182)	399	202	50.6%
729	INEFFECTIVE, OTHER DRUG(S) (99132)	398	24	6.0%
730	Polycythaemia (2521)	397	93	23.4%
731	Elevated protein:creatinine ratio (2533)	397	46	11.6%
732	Corneal disorder NOS (412)	396	37	9.3%
733	Hearing decreased (1512)	396	17	4.3%
734	Lumbar pain (2390)	396	64	16.2%
735	Skin necrosis (967)	395	69	17.5%
736	Mast cell tumour (2729)	394	46	11.7%
737	Stranguria (738)	392	52	13.3%
738	Basophilia (2219)	391	102	26.1%
739	Urination related to convulsion (2772)	391	33	8.4%
740	Fasciculation (688)	390	58	14.9%
741	Granules/Powder, Abnormal (99012)	389	1	0.3%
742	PR-EAR(S), LESION(S) (99610)	389	17	4.4%
743	Application site sore (2602)	389	3	0.8%
744	Confused (1393)	387	29	7.5%
745	Chattering of teeth (1072)	386	19	4.9%
746	PR-HEART, LESION(S) (99619)	385	382	99.2%
747	Splenic neoplasm (1977)	385	240	62.3%
748	Generalised rash (1493)	385	10	2.6%
749	Petechiae NOS (2115)	384	163	42.4%
750	Physical label missing (99849)	383	0	0.0%
751	Disorder of red blood cell NOS (1416)	383	81	21.1%
752	Hair modification NOS (1508)	382	20	5.2%
753	Stroke (639)	382	171	44.8%
754	Proprioception loss (1158)	382	114	29.8%
755	Alopecia general (898)	381	17	4.5%
756	Skin petechiae (1205)	379	131	34.6%
757	Excitation (120)	379	43	11.3%
758	Respiratory sound (1176)	378	134	35.4%
759	Pinnal oedema (363)	378	7	1.9%
760	WBC, URINE (99373)	378	65	17.2%
761	Increased drinking (3130)	378	84	22.2%
762	Cellulitis (970)	377	69	18.3%
763	Residues in milk (2043)	377	5	1.3%
764	Abnormal test result (1221)	377	127	33.7%
765	Weight fluctuation (2596)	377	11	2.9%
766	Renal insufficiency (721)	376	96	25.5%
767	Hyperchloraemia (2577)	375	117	31.2%
768	Allergic pruritus (2076)	375	3	0.8%
769	Monocytopenia (2860)	374	72	19.3%
770	Lung oedema (849)	373	232	62.2%
771	Wrong technique in drug usage process (99865)	373	20	5.4%
772	Platelet disorder NOS (2423)	373	74	19.8%
773	Headache (1511)	372	0	0.0%
774	Spondylosis (1788)	371	95	25.6%
775	Tenesmus (273)	369	51	13.8%
776	Blood and lymphatic system disorder NOS (148)	369	123	33.3%
777	Abdominal cavity haemorrhage (2073)	368	284	77.2%
778	Lot # and/or Expiration date illegible (99844)	368	9	2.4%
779	Jaw disorder (600)	368	53	14.4%
780	Prolonged activated partial thrombin time (APTT) (2210)	368	138	37.5%
781	Hallucination (117)	367	23	6.3%
782	Swollen mouth (1819)	367	1	0.3%
783	Nasal bleeding (863)	367	148	40.3%
784	Application site rash (1331)	367	1	0.3%
785	Administration device NOS, malfunction (93131)	367	0	0.0%
786	Gut sounds increased (1890)	363	14	3.9%
787	Head pressing (636)	363	143	39.4%
788	Increased urine concentration (1962)	363	41	11.3%
789	Lipoma (2062)	363	56	15.4%
790	Paralysis NOS (1677)	363	173	47.7%
791	Missing Cap (99016)	361	1	0.3%
792	Pinnae disorder (1985)	361	13	3.6%
793	Facial pruritus (2877)	361	8	2.2%
794	Application site blister (4)	360	6	1.7%
795	Miscellaneous eating disorder NOS (109)	360	36	10.0%
796	Irritability (1559)	360	27	7.5%
797	Syncope (226)	358	87	24.3%
798	Loss of condition (1044)	358	142	39.7%
799	Ear pruritus (2573)	358	7	2.0%
800	Vasculitis (247)	356	73	20.5%
801	Closed eyelid (1233)	356	16	4.5%
802	Lip smacking (2118)	356	13	3.7%
803	Isosthenuria (2254)	356	53	14.9%
804	Skin tumour NOS (923)	355	40	11.3%
805	Pawing (2592)	354	19	5.4%
806	Purulent lesion(s) (1193)	353	44	12.5%
807	Nasal congestion (1635)	353	51	14.4%
808	Increased weight (1049)	353	33	9.3%
809	Dry eye (472)	352	22	6.3%
810	Pododermatitis (1192)	351	24	6.8%
811	Autoimmune disorder NOS (508)	350	80	22.9%
812	Eye pain (1458)	350	12	3.4%
813	Locking Mechanism Abnormal (99015)	350	3	0.9%
814	Coma (664)	348	225	64.7%
815	Miosis (680)	347	88	25.4%
816	Injection site reddening (1552)	347	10	2.9%
817	Applicator, Abnormal (99000)	346	0	0.0%
818	INEFFECTIVE, PARASITE(S) NOS (99134)	345	52	15.1%
819	Blistering (see also Application site SOC) (1347)	344	16	4.7%
820	Enlarged lymph nodes (generalised) (2426)	344	89	25.9%
821	ULTRASOUND, LIVER ABNORMAL (99369)	343	111	32.4%
822	Injection site mass (2113)	342	17	5.0%
823	Cystitis (725)	341	54	15.8%
824	Dermatosis NOS (941)	340	18	5.3%
825	Hypersensitivity NOS (514)	339	21	6.2%
826	Hyperextension (614)	337	23	6.8%
827	Abnormal urine odour (1966)	337	33	9.8%
828	Crackles on auscultation (2140)	335	170	50.7%
829	Urolithiasis (740)	335	66	19.7%
830	Abnormal red blood cell (2217)	334	105	31.4%
831	Surgical site disorder (2107)	334	49	14.7%
832	Milk production decrease (535)	333	58	17.4%
833	Circling - behavioural disorder (see also Neurological disorders) (2611)	333	44	13.2%
834	Lipaemia (2421)	329	43	13.1%
835	Hepatic disorder NOS (1520)	329	161	48.9%
836	Ear canal erythema (2566)	328	6	1.8%
837	Irregular breathing (838)	326	87	26.7%
838	MICROORGANISMS, URINE (99284)	325	67	20.6%
839	Deafness NOS (368)	324	20	6.2%
840	Implant, Abnormal (99013)	322	2	0.6%
841	Scale (1196)	321	16	5.0%
842	Impaired hearing (1513)	321	18	5.6%
843	Potency, Low (99020)	318	10	3.1%
844	Injection site hair loss (74)	318	3	0.9%
845	Epiphora (436)	315	21	6.7%
846	Dry nose (1219)	314	23	7.3%
847	Needlestick injury (2672)	314	1	0.3%
848	Addison's disease (384)	312	48	15.4%
849	Unconscious (1857)	311	98	31.5%
850	Swollen feet (1812)	311	22	7.1%
851	Liver tumour (505)	311	160	51.4%
852	Elevated haematocrit (2856)	311	44	14.1%
853	Cushings disease NOS (380)	310	54	17.4%
854	Labeled drug-species interaction (99963)	310	41	13.2%
855	Lack of efficacy (virus) - parvovirus (including feline panleukopenia) (2552)	310	93	30.0%
856	Cloudy eye (for Miosis, Mydriasis, Anisocoria, Nystagmus - see 'Neurological') (445)	310	38	12.3%
857	Reverse sneezing (2178)	309	16	5.2%
858	Myoclonic jerk (1631)	307	24	7.8%
859	Blood in faeces NOS (1081)	307	35	11.4%
860	Swollen tongue (1820)	306	31	10.1%
861	Dermal thickening (930)	306	21	6.9%
862	Increased bowel movements (frequency) (2231)	305	14	4.6%
863	Increased seizure frequency (2528)	305	38	12.5%
864	Elevated pancreatic enzymes (2661)	302	68	22.5%
865	Injection site complication NOS (1540)	302	18	6.0%
866	Murmur (214)	300	95	31.7%
867	Lack of efficacy (ectoparasite) - Sarcoptes (2793)	300	0	0.0%
868	Swallowing difficult (1808)	300	63	21.0%
869	Fracture (585)	297	114	38.4%
870	DEATH-TREATMENT FAILURE (99941)	295	294	99.7%
871	Exercise intolerance (1042)	294	49	16.7%
872	Abortion (775)	294	84	28.6%
873	Residues in meat/offal (2042)	294	115	39.1%
874	Anaphylactic shock (1112)	293	73	24.9%
875	Vaginal discharge (1166)	293	34	11.6%
876	Bladder incontinence (1346)	293	66	22.5%
877	Increased skin sensitivity (1535)	291	13	4.5%
878	Lack of efficacy (protozoa) (2655)	291	2	0.7%
879	INEFFECTIVE, LICE BITING (99123)	290	1	0.3%
880	INEFFECTIVE, ASCARIDS (99088)	290	1	0.3%
881	Skin and/or appendage neoplasm NOS (922)	289	38	13.1%
882	Application site dermatitis (1934)	289	8	2.8%
883	Haemoconcentration (2272)	289	60	20.8%
884	Product syringe calibration unreadable (99858)	289	0	0.0%
885	Difficulty going up/down stairs (2869)	289	40	13.8%
886	Tongue ulceration (290)	288	45	15.6%
887	Foam in the mouth (1228)	288	119	41.3%
888	Lack of efficacy (ectoparasite) - mite NOS (2652)	287	5	1.7%
889	Impaired proprioception (1156)	286	57	19.9%
890	Uveitis (435)	285	41	14.4%
891	Tonic-clonic seizure (646)	285	59	20.7%
892	Growling (2755)	284	32	11.3%
893	Cardiomyopathy (205)	283	178	62.9%
894	Peeling skin (944)	283	27	9.5%
895	Injection site serosanguinous discharge (104)	283	22	7.8%
896	Cognitive disorder NOS (1382)	283	78	27.6%
897	Lack of efficacy (fungi) - NOS (2802)	283	2	0.7%
898	Pericardial effusion (237)	282	198	70.2%
899	Skin swelling (969)	282	21	7.4%
900	Bloated stomach (1351)	282	77	27.3%
901	Gastrointestinal foreign body NOS (2562)	282	72	25.5%
902	Atopic allergy NOS (see also 'Skin') (513)	280	10	3.6%
903	Gingivitis (286)	279	27	9.7%
904	Bad taste (1340)	278	0	0.0%
905	Rigidity of limbs (1731)	277	42	15.2%
906	Claw / hoof / nail disorder NOS (1919)	273	43	15.8%
907	Ear canal inflammation (2568)	272	4	1.5%
908	Other blood disorder NOS (1666)	269	82	30.5%
909	Diabetic ketonuria (2054)	265	75	28.3%
910	Injection site warmth (1556)	265	11	4.2%
911	Prolonged one stage prothrombin time (OSPT) (2211)	265	108	40.8%
912	Increased coagulation time (2209)	264	98	37.1%
913	Hyperaemic mucous membrane (1006)	263	68	25.9%
914	Impaired vocalisation (1935)	263	53	20.2%
915	Licking at injection site (2752)	263	13	4.9%
916	Histiocytoma (917)	262	14	5.3%
917	Attention-seeking behaviour (2609)	262	15	5.7%
918	Lack of efficacy (ectoparasite) - Demodex (2789)	259	3	1.2%
919	Hyperventilation (1177)	259	35	13.5%
920	Hyperthyroidism (403)	258	34	13.2%
921	Injection site infection (1542)	257	36	14.0%
922	Injection site mucopurulent discharge (88)	257	21	8.2%
923	Apathy (1212)	257	35	13.6%
924	Mental confusion (1609)	257	31	12.1%
925	Injection site skin discolouration (2202)	257	15	5.8%
926	Injection site seroma (1880)	256	5	2.0%
927	INEFFECTIVE, DELAYED EFFECT (99097)	255	137	53.7%
928	Drug dispensing error (99822)	255	21	8.2%
929	Drug label confusion (3206)	254	5	2.0%
930	Hearing affected (366)	254	8	3.1%
931	Constricted pupils (679)	254	65	25.6%
932	Cardiorespiratory arrest (219)	253	222	87.7%
933	Congested mucous membrane (1007)	252	73	29.0%
934	Inappropriate elimination NOS (2674)	252	67	26.6%
935	Skin abscess (1754)	251	36	14.3%
936	Gastric ulceration NOS (1489)	251	75	29.9%
937	Injected sclera (2462)	251	31	12.4%
938	Lack of efficacy (protozoa) - Ehrlichia (2805)	251	3	1.2%
939	Increased mortality rate (2092)	250	245	98.0%
940	Allergic skin reaction (1306)	249	10	4.0%
941	INEFFECTIVE, REVERSAL (99142)	248	25	10.1%
942	Increased sensitivity to sound (1534)	248	11	4.4%
943	INEFFECTIVE, ESTRUS SYNCHRONIZ (99104)	247	0	0.0%
944	Chronic renal failure (1160)	247	92	37.2%
945	Locomotor disturbance (1248)	246	60	24.4%
946	Small liver (2017)	245	54	22.0%
947	HEMATOCRIT(HCT) HIGH, BLOOD (99314)	244	42	17.2%
948	Abnormal posture (2395)	244	37	15.2%
949	Face and neck swelling (see also 'Skin') (1462)	244	23	9.4%
950	Acidosis (1898)	242	104	43.0%
951	Joint effusion (570)	242	42	17.4%
952	Unusual stool colour (2435)	242	30	12.4%
953	Pollakiuria (1994)	242	17	7.0%
954	Infectious disease NOS (2597)	242	81	33.5%
955	Bronchitis (835)	241	49	20.3%
956	Grooming disorder (1975)	240	15	6.3%
957	Mixed Product (99956)	240	0	0.0%
958	Aural haematoma (350)	239	9	3.8%
959	Oral mass (2230)	239	55	23.0%
960	Increased sweating (974)	238	24	10.1%
961	Drug schedule prescribing error (99829)	238	2	0.8%
962	Blinking (1101)	237	9	3.8%
963	Tympanic rupture (2386)	237	8	3.4%
964	Torn ligament (2581)	237	19	8.0%
965	Retinal disorder NOS (466)	236	36	15.3%
966	Lung sound (1175)	235	98	41.7%
967	Metastatic neoplasia (1926)	234	169	72.2%
968	Brain disorder NOS (1356)	234	130	55.6%
969	Ulcerative dermatitis (936)	233	29	12.4%
970	Local erythema (3129)	233	10	4.3%
971	Lack of coordination (see also 'Ear' - vestibular disorder) (656)	233	28	12.0%
972	Elevated thyroxine (T4) (2669)	230	15	6.5%
973	Demodicosis (2587)	230	5	2.2%
974	Partial blindness (409)	228	30	13.2%
975	Poor coat condition (1996)	228	22	9.6%
976	Application site self trauma (31)	227	2	0.9%
977	Smelly breath (1779)	227	50	22.0%
978	Lack of efficacy (virus) - NOS (2660)	227	54	23.8%
979	Off colour (1028)	225	35	15.6%
980	Bloodshot eye (1353)	224	22	9.8%
981	Bumps on skin (2987)	224	10	4.5%
982	Excessive appetite (136)	222	21	9.5%
983	Circumstance or info capable of leading to medication error (99810)	220	3	1.4%
984	Fixed pupil (431)	219	86	39.3%
985	PR-STOMACH, LESION(S) (99682)	219	164	74.9%
986	Fatigue (1467)	219	21	9.6%
987	Itchy ears (2572)	219	4	1.8%
988	Bradypnoea (833)	217	65	30.0%
989	Otorrhoea (348)	217	3	1.4%
990	Genital tract licking (2478)	216	4	1.9%
991	Small intestine ulcer (1087)	215	115	53.5%
992	Haemangiosarcoma (2072)	215	133	61.9%
993	Injection site mass NOS (2113)	214	16	7.5%
994	Ileus (1086)	213	45	21.1%
995	Injection site pruritus (97)	213	5	2.3%
996	Ear twitching (1138)	213	18	8.5%
997	Drug dose prescribing error (93075)	213	3	1.4%
998	INEFFECTIVE, ANALGESIA (99081)	212	9	4.2%
999	Labels, Abnormal (99014)	212	2	0.9%
1000	Ear irritation (1436)	212	8	3.8%
1001	Aspiration pneumonia (2778)	212	93	43.9%
1002	Blood loss NOS (1352)	212	90	42.5%
1003	Hyperadrenocorticism (379)	211	31	14.7%
1004	Opisthotonus (644)	211	74	35.1%
1005	Self mutilation (1222)	211	11	5.2%
1006	Chewing - oral cavity disorder (see also 'Pruritus') (1073)	211	9	4.3%
1007	Skin haemorrhage NOS (2748)	211	24	11.4%
1008	Seborrhoea (911)	210	11	5.2%
1009	Application site skin scaling (2198)	210	4	1.9%
1010	Epilepsy (647)	209	19	9.1%
1011	Epileptic seizure (648)	209	19	9.1%
1012	Drug prescribing error (99828)	209	7	3.3%
1013	Puncture wound (2672)	209	0	0.0%
1014	INEFFECTIVE, STRONGYLES (99151)	208	30	14.4%
1015	Application site hair coat discolouration (2519)	208	2	1.0%
1016	PR-LUNG(S), EDEMA (99630)	207	207	100.0%
1017	Food allergy (1481)	207	2	1.0%
1018	Administration device NOS, abnormal (93147)	207	0	0.0%
1019	Gum disorder NOS (1501)	206	38	18.4%
1020	Hypermetria (662)	205	29	14.1%
1021	Palpebral disorder NOS (426)	205	37	18.0%
1022	Heart valve disorder (1515)	205	80	39.0%
1023	Leukocytosis NOS (163)	205	51	24.9%
1024	INEFFECTIVE, PRODUCTION (MILK) (99140)	204	3	1.5%
1025	Stress leukogram (2589)	204	42	20.6%
1026	Glaucoma (417)	203	33	16.3%
1027	Anal irritation (2059)	203	9	4.4%
1028	Increased sexual interest (2067)	202	44	21.8%
1029	Loss of voluntary movement (1597)	202	50	24.8%
1030	Digestive tract haemorrhage NOS (306)	201	108	53.7%
1031	Stillbirth (791)	201	77	38.3%
1032	Disorder of gastrointestinal flora (2563)	201	33	16.4%
1033	PR-SPLEEN, LESION(S) (99679)	200	180	90.0%
1034	Schirmer tear test (2666)	200	6	3.0%
1035	Low serum alkaline phosphatase (ALP) (2690)	200	33	16.5%
1036	Calculi (741)	199	51	25.6%
1037	Tongue oedema (1077)	199	21	10.6%
1038	Eye itching (1457)	199	3	1.5%
1039	Tense muscles (2248)	199	15	7.5%
1040	Harsh lung sounds (2487)	199	91	45.7%
1041	Anal and rectal disorder NOS (2560)	199	25	12.6%
1042	Duodenal ulcer (1088)	198	93	47.0%
1043	Stomach pain (1799)	198	11	5.6%
1044	Haemolysis (2156)	198	24	12.1%
1045	INEFFECTIVE, EAR MITES (99100)	198	0	0.0%
1046	Drowsiness - systemic disorder (2530)	198	14	7.1%
1047	Less social (2411)	197	28	14.2%
1048	Skin oedema (968)	196	36	18.4%
1049	Burning sensation of eye (1368)	196	0	0.0%
1050	Localised skin reaction (1585)	196	9	4.6%
1051	Disseminated intravascular coagulation (154)	195	165	84.6%
1052	Alteration of milk quality (533)	194	19	9.8%
1053	Itchy rash (1563)	194	2	1.0%
1054	Dry mouth (295)	193	15	7.8%
1055	Coprophagia (133)	193	4	2.1%
1056	Cardiac murmur (212)	193	52	26.9%
1057	Lack of efficacy (neoplasia, no remission) (2891)	193	36	18.7%
1058	Other immune system disorder NOS (522)	192	42	21.9%
1059	Joint pain NOS (586)	192	17	8.9%
1060	Adaptor, breakage (93135)	192	0	0.0%
1061	Gingival disorder (1885)	191	26	13.6%
1062	Product dropper issue (99854)	191	0	0.0%
1063	Dizziness (1422)	191	0	0.0%
1064	Muscle rigidity (1628)	191	35	18.3%
1065	Decreased pulse oxygenation (2486)	191	95	49.7%
1066	Enlarged kidney(s) (2253)	191	83	43.5%
1067	Bloody stool (3071)	191	26	13.6%
1068	Injection site ulcer (106)	190	16	8.4%
1069	Capsules, Abnormal (99037)	190	0	0.0%
1070	Stomatitis (300)	188	24	12.8%
1071	Oliguria (711)	188	63	33.5%
1072	Cutaneous calcinosis (2079)	187	25	13.4%
1073	Injection site weeping (see also Skin) (103)	187	15	8.0%
1074	Central nervous system disorder NOS (631)	186	72	38.7%
1075	Neuromuscular disorder NOS (1649)	186	40	21.5%
1076	Peripheral nervous system disorder NOS (1906)	185	50	27.0%
1077	Coughing up blood (1970)	185	63	34.1%
1078	Thyroid gland disorder NOS (405)	185	50	27.0%
1079	Epidermal collarette (2263)	185	8	4.3%
1080	BANDS(NEUTROPHILS) HIGH, BLOOD (99189)	184	67	36.4%
1081	Prolapse of the nictitating membrane (1103)	184	23	12.5%
1082	Sternoabdominal recumbency (1136)	183	65	35.5%
1083	Mammary gland disorder NOS (527)	182	37	20.3%
1084	Swallowing disorder NOS (1809)	182	21	11.5%
1085	Ruminal bloat (320)	181	159	87.8%
1086	Acidic urine (1951)	181	40	22.1%
1087	Third eyelid extrusion (449)	181	19	10.5%
1088	Prolonged bleeding NOS (151)	180	58	32.2%
1089	Mastitis NOS (1988)	180	65	36.1%
1090	Pigmentation disorder (1188)	180	6	3.3%
1091	Slow heart rate (190)	180	32	17.8%
1092	Injection site irritation (94)	179	4	2.2%
1093	Dependent oedema (1229)	178	41	23.0%
1094	Tracheal collapse (879)	178	61	34.3%
1095	Cognitive impairment (1384)	178	50	28.1%
1096	Decreased respiratory rate (834)	177	54	30.5%
1097	Vascular disorder NOS (see also endocarditis) (246)	177	70	39.5%
1098	Ptyalism (1075)	177	34	19.2%
1099	Choke (2584)	177	41	23.2%
1100	Lack of awareness (1020)	176	29	16.5%
1101	Fluid in thorax (1183)	176	115	65.3%
1102	Gastric distension (1092)	176	60	34.1%
1103	Ear canal disorder (2567)	176	12	6.8%
1104	Agonal breathing (2777)	176	154	87.5%
1105	PR-LYMPH NODE(S), LESION(S) (99632)	175	109	62.3%
1106	Hepatic neoplasm (507)	175	116	66.3%
1107	HEMOGLOBIN(HB) HIGH, BLOOD (99310)	175	24	13.7%
1108	Premature ventricular contractions (2434)	175	39	22.3%
1109	Elevated lactate (2852)	175	82	46.9%
1110	Paraparesis (699)	174	51	29.3%
1111	Cough, productive (2260)	174	24	13.8%
1112	Decreased blood urea nitrogen (BUN) or creatinine (2702)	174	42	24.1%
1113	Illness NOS (99950)	173	32	18.5%
1114	Angioedema (516)	173	2	1.2%
1115	Strabismus (1895)	172	46	26.7%
1116	Stridor (Upper respiratory; for lower respiratory see also Bronchial rale) (1953)	172	42	24.4%
1117	Reduced reflexes (676)	172	49	28.5%
1118	Myositis (612)	171	68	39.8%
1119	Piloerection (910)	171	5	2.9%
1120	Hypoxia (2186)	171	59	34.5%
1121	Abrasion (2594)	171	8	4.7%
1122	Dysphagia (285)	170	30	17.6%
1123	Depressed reflexes (677)	170	57	33.5%
1124	Defecation related to convulsion (2771)	170	17	10.0%
1125	Product label information incorrect (99856)	169	0	0.0%
1126	Corneal oedema (413)	169	17	10.1%
1127	PR-SMALL INTESTINE, LESION(S) (99676)	169	143	84.6%
1128	Inappropriate packaging or design (99974)	169	0	0.0%
1129	Loss of condition score (1045)	169	57	33.7%
1130	Administration device NOS, damaged (93146)	169	0	0.0%
1131	Not defecating (3066)	169	40	23.7%
1132	Hyperkeratosis (896)	168	18	10.7%
1133	Tingling sensation (1841)	168	0	0.0%
1134	Involuntary movement (1558)	168	18	10.7%
1135	Laceration (2509)	167	21	12.6%
1136	Increased band neutrophilia (2859)	167	49	29.3%
1137	Low weight gain (1048)	165	32	19.4%
1138	Fainting (227)	165	35	21.2%
1139	Scaly condition NOS (1735)	165	10	6.1%
1140	Neuropathy NOS (1650)	165	35	21.2%
1141	Retinal detachment (465)	163	33	20.2%
1142	Bronchopneumonia (2139)	163	112	68.7%
1143	Drug device difficult to use/handle (93090)	163	1	0.6%
1144	Meningitis (637)	162	47	29.0%
1145	Pancytopenia (2114)	162	50	30.9%
1146	Haemolysis NOS (2156)	162	27	16.7%
1147	Dazed (3109)	162	21	13.0%
1148	Muscle pain (608)	161	14	8.7%
1149	Increased lung sounds (2488)	161	63	39.1%
1150	Lack of efficacy (1039)	161	26	16.1%
1151	Leukopenia NOS (164)	161	24	14.9%
1152	Mouth pain (1623)	160	13	8.1%
1153	Belching (337)	160	9	5.6%
1154	Blood clot (153)	159	86	54.1%
1155	SKIN SCRAPING ABNORMAL (99353)	158	3	1.9%
1156	Application site dry skin (2514)	158	2	1.3%
1157	Application site infection (2005)	158	5	3.2%
1158	Low tear flow (1102)	158	2	1.3%
1159	Accidental drug intake by child (99908)	157	0	0.0%
1160	Throat irritation (1836)	157	9	5.7%
1161	Splenic neoplasm NOS (1977)	157	80	51.0%
1162	Delayed healing (2081)	156	18	11.5%
1163	Retinal degeneration (463)	156	18	11.5%
1164	Swollen joint (1816)	156	26	16.7%
1165	Abnormal necropsy finding (2142)	156	150	96.2%
1166	Lip disorder NOS (2446)	156	15	9.6%
1167	Increased urine volume (2773)	155	27	17.4%
1168	Skin discolouration NOS (2881)	155	12	7.7%
1169	Folliculitis (904)	154	13	8.4%
1170	Lot # and/or Expiration date incorrect (99845)	154	1	0.6%
1171	Third eyelid prolapse (1104)	154	12	7.8%
1172	Neurogenic keratoconjunctivitis sicca (KCS) (2866)	154	9	5.8%
1173	High ionized calcium (Ca; Hypercalcemia, ionized) (2684)	153	27	17.6%
1174	Contamination, Mold (99007)	152	3	2.0%
1175	Product dropper missing (99855)	152	0	0.0%
1176	Application site weeping (see also 'skin') (32)	152	1	0.7%
1177	Haemoptysis (846)	151	54	35.8%
1178	Injection site granuloma (78)	151	4	2.6%
1179	Joint stiffness (573)	151	20	13.2%
1180	Pulmonary haemorrhage (847)	151	144	95.4%
1181	Downer animal (2172)	151	109	72.2%
1182	Bulging eye (2380)	151	29	19.2%
1183	Quadriparesis (700)	150	44	29.3%
1184	Nephropathy (717)	150	51	34.0%
1185	Application site excoriation (2194)	150	1	0.7%
1186	Ligament rupture (2580)	150	16	10.7%
1187	Abnormal histology NOS (2864)	150	48	32.0%
1188	PR-INTEST, LESION(S) (99623)	149	122	81.9%
1189	Abnormal ECG (2158)	149	61	40.9%
1190	Physical product label issues (99850)	149	0	0.0%
1191	Burning sensation (skin) (1367)	149	0	0.0%
1192	Application site skin discolouration (2197)	149	2	1.3%
1193	Administration device NOS, priming issue (93149)	149	0	0.0%
1194	Inappropriate preparation of medication (99831)	148	36	24.3%
1195	Internal ear disorder (369)	148	16	10.8%
1196	Excess tear flow (438)	148	11	7.4%
1197	Prescribing error (3040)	148	9	6.1%
1198	PR-PANCREAS, LESION(S) (99658)	147	138	93.9%
1199	Rectal prolapse (257)	147	63	42.9%
1200	Unthrifty (1933)	147	56	38.1%
1201	Active urine sediment (2699)	147	28	19.0%
1202	Osteosarcoma (619)	147	67	45.6%
1203	Pruritic rash (1709)	147	1	0.7%
1204	Myelopathy NOS (2173)	147	43	29.3%
1205	Swollen muzzle (2905)	147	1	0.7%
1206	Hyphaemia (418)	146	54	37.0%
1207	Gastric bloat (1090)	146	64	43.8%
1208	Encephalitis (633)	146	76	52.1%
1209	Nasal cavity disorder NOS (1634)	146	30	20.5%
1210	Abnormal vision (see also impaired vision) (1293)	146	19	13.0%
1211	Generalised skin reaction (1495)	146	8	5.5%
1212	Low serum alkaline phosphatase (SAP) (2690)	146	19	13.0%
1213	Haematoma NOS (2088)	145	44	30.3%
1214	Female reproductive tract disorder NOS (769)	144	20	13.9%
1215	Facial nerve disorder (1148)	144	25	17.4%
1216	Inflammatory bowel disorder (2843)	144	27	18.8%
1217	Laryngeal paralysis (1991)	143	50	35.0%
1218	Application site lump (21)	143	3	2.1%
1219	Skin textural change (1832)	143	6	4.2%
1220	Mouth ulcer (1624)	143	26	18.2%
1221	Pinnal irritation (361)	142	4	2.8%
1222	Difficulty eating NOS (2847)	142	37	26.1%
1223	Involuntary urination (3116)	142	33	23.2%
1224	Skin reaction NOS (2876)	141	6	4.3%
1225	Obtunded (3108)	141	84	59.6%
1226	Dehiscence, medical device (93032)	140	9	6.4%
1227	Ventricular arrhythmia (2222)	139	53	38.1%
1228	Haemolytic anaemia (147)	139	51	36.7%
1229	INEFFECTIVE, ESTRUS SUPPRESSIO (99103)	139	8	5.8%
1230	Injection site serous discharge (105)	139	11	7.9%
1231	Unsettled (2673)	138	7	5.1%
1232	Megaoesophagus (274)	137	53	38.7%
1233	Drowsiness - neurological disorder (1282)	137	6	4.4%
1234	Pyelonephritis (716)	137	51	37.2%
1235	White blood cell disorder NOS (2861)	137	39	28.5%
1236	Vaginal haemorrhage (817)	136	20	14.7%
1237	Tracheal and laryngeal disorder NOS (1849)	136	45	33.1%
1238	Other coagulation abnormality NOS (152)	135	52	38.5%
1239	Vaginal swelling (827)	135	8	5.9%
1240	Laminitis (617)	135	31	23.0%
1241	Cholangiohepatitis (476)	135	43	31.9%
1242	Abnormal serum protein NOS (2220)	135	21	15.6%
1243	Decreased mean corpuscular volume (MCV) (2855)	135	43	31.9%
1244	Hemiparesis (weakness L or R side) (697)	134	36	26.9%
1245	Dehiscence (2080)	134	27	20.1%
1246	Panic (2610)	134	13	9.7%
1247	Gastric dilation (1091)	133	72	54.1%
1248	Generalised allergic reaction NOS (1115)	133	10	7.5%
1249	Pitting oedema (2887)	133	35	26.3%
1250	Pulmonary neoplasm (1918)	132	97	73.5%
1251	Mucosa petechiae (1213)	132	54	40.9%
1252	Granuloma (950)	132	14	10.6%
1253	Application site mucopurulent discharge (17)	132	3	2.3%
1254	Hepatic necrosis (491)	132	108	81.8%
1255	Reduced level of consciousness (1724)	132	38	28.8%
1256	Periodontal disorder (2225)	132	26	19.7%
1257	Cyanotic mucous membranes (2988)	132	62	47.0%
1258	Digestive tract hypomotility (2163)	131	34	26.0%
1259	Injection site hair change (2149)	131	0	0.0%
1260	Cold feeling to the touch (2741)	131	50	38.2%
1261	Moribund (1040)	130	107	82.3%
1262	Eye inflammation NOS (1456)	130	17	13.1%
1263	Missing component, medical device (93020)	130	0	0.0%
1264	Fear/fearful (3062)	130	10	7.7%
1265	Protrusion membrana nictitans (448)	129	13	10.1%
1266	Oral swelling (2444)	129	9	7.0%
1267	Elevated SAP (2055)	129	22	17.1%
1268	Suspect counterfeit product (2281)	129	5	3.9%
1269	Suspected infectious agent transmission (1925)	128	51	39.8%
1270	Chemosis (1107)	128	5	3.9%
1271	Sunken eyes (2273)	128	45	35.2%
1272	Injection site skin change NOS (2205)	128	3	2.3%
1273	INEFFECTIVE, WEIGHT LOSS (99949)	127	0	0.0%
1274	Mammary gland neoplasm NOS (529)	127	40	31.5%
1275	HYPERBILIRUBINEMIA (99201)	127	46	36.2%
1276	Melanoma (918)	127	30	23.6%
1277	Low pancreatic enzymes (2694)	127	23	18.1%
1278	Cyst NOS (2884)	127	15	11.8%
1279	Swollen eyelid (see also Eyelid disorders in Eye disorders) (2766)	127	1	0.8%
1280	Infertility NOS (764)	126	4	3.2%
1281	Flatulence, bloating and distension (1477)	126	21	16.7%
1282	Extensor rigidity (1127)	126	36	28.6%
1283	Hiccup (2090)	126	4	3.2%
1284	Large platelets (2425)	126	30	23.8%
1285	Motor dysfunction NOS (1620)	126	27	21.4%
1286	Numbness (1972)	125	5	4.0%
1287	Generalised red spot (1494)	125	3	2.4%
1288	Heart block NOS (191)	124	13	10.5%
1289	Thrombosis (156)	124	102	82.3%
1290	Hypomagnesaemic condition (564)	123	32	26.0%
1291	Birth defect (776)	123	63	51.2%
1292	Lens disorder NOS (446)	123	15	12.2%
1293	Joint ligament disorder NOS (2465)	123	13	10.6%
1294	Lung tumour (1917)	123	69	56.1%
1295	Digestive tract neoplasm NOS (307)	122	86	70.5%
1296	Plantigrade posture (2632)	122	13	10.7%
1297	Eruption (1190)	121	9	7.4%
1298	Skin dryness (1428)	121	4	3.3%
1299	Skin sarcoma NOS (921)	121	20	16.5%
1300	Burn (926)	120	3	2.5%
1301	Breathlessness (1915)	120	32	26.7%
1302	Groaning (2393)	120	35	29.2%
1303	Wide-base stance (2633)	120	16	13.3%
1304	Reduced food intake (2783)	120	20	16.7%
1305	Neck pain - neurological (2872)	120	24	20.0%
1306	Eye haemorrhage (1099)	119	40	33.6%
1307	Dry heaving (3074)	119	20	16.8%
1308	Mixed Product Strength (99957)	119	0	0.0%
1309	Papular rash (1673)	119	5	4.2%
1310	Elevated betahydroxybutyrate (BHP) (3193)	119	8	6.7%
1311	Scleritis (473)	118	16	13.6%
1312	INEFFECTIVE, HEARTWORM MICROFI (99117)	118	1	0.8%
1313	Prostration (1017)	118	27	22.9%
1314	Teeth grinding (128)	117	17	14.5%
1315	Mental function decreased (1611)	117	40	34.2%
1316	Cold feeling of extremity (1386)	117	51	43.6%
1317	Nervous (3063)	117	5	4.3%
1318	Rotatory nystagmus (2637)	117	14	12.0%
1319	Urinary tenesmus (726)	116	23	19.8%
1320	Droopy ear (355)	116	16	13.8%
1321	Multi-organ failure NOS (1041)	116	106	91.4%
1322	Panniculitis (951)	116	20	17.2%
1323	Subdued (2646)	116	11	9.5%
1324	Joint inflammation (571)	115	18	15.7%
1325	Physical label damaged (99847)	115	0	0.0%
1326	Uncontrolled diabetes (388)	115	24	20.9%
1327	Elevated betahydroxybutyrate (BHBA) (3193)	115	4	3.5%
1328	Mammary gland oedema (528)	114	12	10.5%
1329	Application site oedema (19)	114	0	0.0%
1330	Abdominal cramp (262)	114	3	2.6%
1331	Greasy skin (912)	114	4	3.5%
1332	Luxation/subluxation (2912)	114	18	15.8%
1333	Hard stool (2677)	114	24	21.1%
1334	Tear flow increased (437)	113	9	8.0%
1335	Wheal (520)	112	1	0.9%
1336	Broken components, medical device (93021)	112	0	0.0%
1337	Eyelid erythema (2460)	112	1	0.9%
1338	Nervous system neoplasm (669)	111	69	62.2%
1339	Foreign body, medical device (93030)	111	2	1.8%
1340	Otitis media (377)	111	12	10.8%
1341	Asthma (832)	111	25	22.5%
1342	Counterfeit product (2281)	111	2	1.8%
1343	Elevated haemoglobin (3089)	111	11	9.9%
1344	Hyperreflexia (678)	110	18	16.4%
1345	Wart (1199)	110	5	4.5%
1346	Injection site itching (95)	110	2	1.8%
1347	INEFFECTIVE, DEMODEX MITES (99098)	110	0	0.0%
1348	Mouth irritation (245)	109	4	3.7%
1349	Nasal cavity and sinus disorder NOS (865)	108	15	13.9%
1350	Voice alteration (1269)	108	10	9.3%
1351	Discus prolapse (599)	108	25	23.1%
1352	Acid-base disorder (540)	108	34	31.5%
1353	Heart pounding (1514)	108	14	13.0%
1354	Lick granuloma (2264)	108	6	5.6%
1355	Gel/Paste, Abnormal (99011)	107	3	2.8%
1356	Injection site crust (87)	107	3	2.8%
1357	Reduced conception rate (1163)	107	4	3.7%
1358	Lack of efficacy, medical device (93022)	107	5	4.7%
1359	PR-INJECTION SITE, LESION(S) (99622)	106	51	48.1%
1360	Contamination, Insects (99006)	106	0	0.0%
1361	Painful defecation (1983)	106	21	19.8%
1362	Gall bladder inflammation (478)	106	30	28.3%
1363	Partial adipsia (2590)	106	19	17.9%
1364	Injection site panniculitis (1053)	106	3	2.8%
1365	Peritoneal fluid, abnormal NOS (2715)	106	51	48.1%
1366	Pyometra (812)	105	21	20.0%
1367	Injection site stiffness (1553)	105	10	9.5%
1368	Hyperaemia (1008)	105	20	19.0%
1369	Decreased mean corpuscular haemoglobin concentration (MCHC) (3090)	105	25	23.8%
1370	Lack of efficacy (neoplasia, partial remission) (2892)	105	4	3.8%
1371	Spinal pain NOS (3104)	105	30	28.6%
1372	Hyperhidrosis (975)	104	13	12.5%
1373	Congestion of mucous membrane (1002)	104	27	26.0%
1374	Nephritis (714)	104	63	60.6%
1375	Furunculosis (1486)	104	9	8.7%
1376	Pulmonary thromboembolism (851)	104	56	53.8%
1377	Sensation loss (1739)	104	35	33.7%
1378	Application site hot spot (2407)	104	0	0.0%
1379	Lack of efficacy (mycoplasma) - NOS (2654)	104	71	68.3%
1380	Vomiting foam (3073)	104	20	19.2%
1381	Excessive ear wax (2759)	103	6	5.8%
1382	PR-BRAIN, LESION(S) (99595)	102	99	97.1%
1383	Facial rash (For urticaria see Immune SOC) (1465)	102	4	3.9%
1384	Injection site sarcoma (101)	102	19	18.6%
1385	Difficulty chewing (2450)	102	7	6.9%
1386	Agglutination test, positive (2696)	102	37	36.3%
1387	Vesicle (1866)	101	6	5.9%
1388	Cachexia (1051)	101	62	61.4%
1389	MRI SCAN ABNORMAL (99288)	101	30	29.7%
1390	Eructation (336)	101	6	5.9%
1391	Light headedness (1576)	101	0	0.0%
1392	Loose bowel (1588)	101	8	7.9%
1393	Idiopathic vestibular disease (2458)	101	12	11.9%
1394	INEFFECTIVE, SARCOPTES MITES (99144)	101	0	0.0%
1395	Elevated mean corpuscular volume (MCV) (2854)	101	20	19.8%
1396	POLYCYTHEMIA, RELATIVE (99318)	100	20	20.0%
1397	Circulatory shock (221)	100	57	57.0%
1398	Impaired swallowing (284)	100	38	38.0%
1399	Lymphosarcoma (172)	100	49	49.0%
1400	Mucus in eye (1625)	100	17	17.0%
1401	Elevated ALT (2050)	100	23	23.0%
1402	Ear flap oedema (364)	99	2	2.0%
1403	INEFFECTIVE, LICE SUCKING (99124)	98	1	1.0%
1404	Cranial nerve disorder (1147)	98	33	33.7%
1405	Product syringe improperly calibrated (99859)	98	0	0.0%
1406	Acting tense (2206)	98	3	3.1%
1407	Dysuria (727)	97	17	17.5%
1408	Digestive tract stenosis and obstruction NOS (310)	97	26	26.8%
1409	Symptom NOS involving neurological and muscular skeletal SOCs (1822)	97	33	34.0%
1410	Feeling anxious (1468)	97	0	0.0%
1411	Lockjaw (1587)	97	20	20.6%
1412	Unkempt hair coat (2757)	97	22	22.7%
1413	Foam in the nose (1178)	96	61	63.5%
1414	Cardiac failure (196)	96	68	70.8%
1415	Seroma (963)	96	12	12.5%
1416	Unequal pupils (671)	96	10	10.4%
1417	Pustular skin eruption (1715)	96	6	6.3%
1418	Injection site nodule (2605)	96	2	2.1%
1419	Respiratory depression (1168)	95	31	32.6%
1420	Vision blurred (1870)	95	0	0.0%
1421	Yellow mucous membranes (500)	95	49	51.6%
1422	Chemical burn (928)	95	6	6.3%
1423	Increased intra-ocular pressure (2234)	95	18	18.9%
1424	Head twitching (3110)	95	12	12.6%
1425	Dry coat (1995)	94	5	5.3%
1426	Iris disorder (428)	93	21	22.6%
1427	Urinary tract neoplasm (742)	93	40	43.0%
1428	Application site serous discharge (34)	93	1	1.1%
1429	Anterior uveitis (433)	93	14	15.1%
1430	Unable to focus (1856)	93	6	6.5%
1431	Intention tremor (2249)	93	9	9.7%
1432	Bladder distension (2639)	92	27	29.3%
1433	Injection site tenderness (2751)	92	7	7.6%
1434	Out of specification (93152)	92	0	0.0%
1435	Injection site discharge NOS (3056)	92	7	7.6%
1436	Cough, hacking (3123)	92	15	16.3%
1437	Elevated fructosamine (3192)	92	2	2.2%
1438	Sensory abnormality NOS (1740)	91	5	5.5%
1439	Gastric volvulus (339)	91	62	68.1%
1440	Application site pyoderma (28)	91	2	2.2%
1441	Pemphigus foliaceus (1225)	91	15	16.5%
1442	Rough recovery (2503)	91	13	14.3%
1443	Skin haematoma (1757)	90	14	15.6%
1444	Photophobia (704)	90	7	7.8%
1445	Dermal nodule (2780)	90	10	11.1%
1446	Hepato-biliary disorder NOS (2018)	89	33	37.1%
1447	Injection site self trauma (102)	89	3	3.4%
1448	Spleen hypertrophy (1059)	89	32	36.0%
1449	Swollen ear canal (2571)	89	1	1.1%
1450	Liver nodules (2904)	89	38	42.7%
1451	Tympanic alteration (2621)	89	10	11.2%
1452	Cervical pain (2769)	89	17	19.1%
1453	RED BLOOD CELLS(RBC) NUCLEATED (99336)	88	25	28.4%
1454	Difficulty in micturition (1410)	88	19	21.6%
1455	Excessive sweating (1453)	88	13	14.8%
1456	Necrosis NOS (2889)	88	38	43.2%
1457	Pyloric ulcer (1717)	87	32	36.8%
1458	PR-GI, LESION(S) (99615)	87	72	82.8%
1459	Torticollis (594)	87	28	32.2%
1460	INEFFECTIVE, LUNGWORMS (99126)	87	20	23.0%
1461	Localised numbness (see also application site SOC) (1958)	87	2	2.3%
1462	Uncontrolled micturition (736)	87	18	20.7%
1463	Bone marrow disorder NOS (1882)	87	44	50.6%
1464	Droopy lower lip (2454)	87	7	8.0%
1465	Low ionized calcium (Ca; Hypocalcaemia, ionized) (2686)	87	39	44.8%
1466	Eyelid inflammation (422)	86	3	3.5%
1467	Vaginitis (822)	86	8	9.3%
1468	Conjunctival oedema (1108)	86	5	5.8%
1469	Application site pustule (27)	86	0	0.0%
1470	Injection site dermatitis (1938)	86	5	5.8%
1471	Hypercortisolaemia (2624)	86	23	26.7%
1472	Alkalosis (2075)	86	22	25.6%
1473	INEFFECTIVE, WEIGHT INC (99157)	85	23	27.1%
1474	Pupil disorder (432)	85	13	15.3%
1475	Impaired gastric function (1894)	85	23	27.1%
1476	Leukaemia (171)	85	53	62.4%
1477	Dental plaque (2228)	85	9	10.6%
1478	Sarcoma NOS (2973)	85	24	28.2%
1479	Lichenification (2037)	84	2	2.4%
1480	Slow reflexes (674)	84	14	16.7%
1481	Pulmonary hypertension (2559)	84	18	21.4%
1482	Haemoglobinuria (2027)	83	25	30.1%
1483	Erosion (945)	83	3	3.6%
1484	Red mucosae (1003)	83	19	22.9%
1485	Injection site scratching (96)	83	0	0.0%
1486	Papillomatosis (952)	83	0	0.0%
1487	Petit mal epilepsy (1694)	83	6	7.2%
1488	Destructive behaviour (2388)	83	8	9.6%
1489	Elevated mean corpuscular haemoglobin concentration (MCHC) (3091)	83	12	14.5%
1490	Steatitis (1036)	82	23	28.0%
1491	Blepharitis (421)	82	2	2.4%
1492	Injection site haematoma (80)	82	14	17.1%
1493	Potency, High (99019)	81	9	11.1%
1494	Wrong strength dispensed (93079)	81	3	3.7%
1495	Hissing (2754)	81	5	6.2%
1496	INEFFECTIVE, NEOPLASIA (93007)	81	8	9.9%
1497	Penile disorder NOS (796)	80	8	10.0%
1498	Erythema multiforme (1197)	80	9	11.3%
1499	Cardiac neoplasm (2309)	80	54	67.5%
1500	Hernia NOS (1521)	80	17	21.3%
1501	Increased yawning (2501)	80	0	0.0%
1502	Renal tubular disorder (2145)	80	60	75.0%
1503	Dilated renal pelvis (1993)	80	26	32.5%
1504	Increased sensitivity to light (1695)	80	1	1.3%
1505	Low alanine aminotransferase (ALT) (2688)	80	10	12.5%
1506	Hip dysplasia (2725)	80	19	23.8%
1507	Equilibrium disorder (371)	79	15	19.0%
1508	Thromboemboli (155)	79	56	70.9%
1509	Insert, Damaged (99976)	79	0	0.0%
1510	Scar (2544)	79	3	3.8%
1511	Abnormal electrocardiogram (ECG) (2158)	79	19	24.1%
1512	Application site necrosis (18)	78	6	7.7%
1513	Urticarial rash (1860)	78	0	0.0%
1514	Abnormal Schirmer tear test (2666)	78	7	9.0%
1515	INEFFECTIVE, APPETITE SUPPRESSION (99087)	77	0	0.0%
1516	Tracheitis (882)	77	19	24.7%
1517	Cutaneous oedema (1204)	77	20	26.0%
1518	Polyarthritis (574)	77	15	19.5%
1519	Urticarial erythema (1859)	77	2	2.6%
1520	Application site twitching (2196)	77	1	1.3%
1521	Thoracic cavity disorder NOS (2372)	77	39	50.6%
1522	Drug preparation error (93086)	77	3	3.9%
1523	Lack of efficacy (endoparasite) - Toxocara/Toxascaris (2826)	77	0	0.0%
1524	Dermal plaque (2781)	77	1	1.3%
1525	Necrotic wound (2890)	77	12	15.6%
1526	Spleen nodules (2900)	77	30	39.0%
1527	Oesophagitis (276)	76	19	25.0%
1528	Elevated fibrinogen level (2268)	76	25	32.9%
1529	Prostatic disorder NOS (1165)	76	24	31.6%
1530	Facial palsy (1464)	76	8	10.5%
1531	Chronic pancreatitis (1892)	76	18	23.7%
1532	Lack of efficacy (bacteria) - Leptospira (2787)	76	32	42.1%
1533	Adaptor, abnormal (93133)	76	0	0.0%
1534	Local skin slough (3128)	76	8	10.5%
1535	Hypersensitivity to movement (707)	75	5	6.7%
1536	Hypersensitivity to light (705)	75	2	2.7%
1537	Vitamin deficiency (552)	75	18	24.0%
1538	Lip erythema (2447)	75	1	1.3%
1539	Tooth loss (2448)	75	13	17.3%
1540	Gall bladder mucocele (2627)	75	28	37.3%
1541	Allergic oedema (515)	74	3	4.1%
1542	Cervical ventroflexion (2123)	74	25	33.8%
1543	Keratitis (416)	74	7	9.5%
1544	Coughing blood (1259)	74	26	35.1%
1545	Bronchopulmonary inflammation (2294)	74	15	20.3%
1546	Vertical nystagmus (2638)	74	16	21.6%
1547	Abnormal tail posture (3107)	74	14	18.9%
1548	MAGNESIUM HIGH, BLOOD (99282)	73	32	43.8%
1549	Synovitis (623)	73	8	11.0%
1550	Depressed ocular reflex (1098)	73	22	30.1%
1551	Muscle contracture (2468)	73	13	17.8%
1552	Mopey (2782)	73	2	2.7%
1553	Embolism (208)	72	42	58.3%
1554	Ear flapping/twitching (1986)	72	0	0.0%
1555	Fatty liver (483)	72	41	56.9%
1556	Tail paresis (2171)	72	8	11.1%
1557	Rapid pulse rate (1719)	72	19	26.4%
1558	Miliary dermatitis (2261)	72	1	1.4%
1559	Elevated BUN (2047)	72	28	38.9%
1560	Immediate pain upon application (2408)	72	0	0.0%
1561	IGA Animal mortality greater than expected (93102)	72	72	100.0%
1562	Urinary tract obstruction/blockage (2874)	72	10	13.9%
1563	Prolonged anaesthesia (1218)	71	12	16.9%
1564	Glomerulonephritis (713)	71	50	70.4%
1565	Intestinal stasis (1066)	71	14	19.7%
1566	Enlarged pupils (689)	71	4	5.6%
1567	Blotchy rash (1354)	71	1	1.4%
1568	Eye inflamed (1455)	71	4	5.6%
1569	Renal degeneration (2126)	71	32	45.1%
1570	Application site thickening (2515)	71	2	2.8%
1571	Status epilepticus (2473)	71	44	62.0%
1572	Administration device NOS, missing component (93145)	71	0	0.0%
1573	Lack of efficacy (neoplasia, relapse) (2893)	71	8	11.3%
1574	Digestive tract hypermotility (1889)	70	6	8.6%
1575	Vulvitis (823)	70	5	7.1%
1576	Musculoskeletal neoplasm NOS (1122)	70	37	52.9%
1577	Hyporeflexia (1220)	70	29	41.4%
1578	Application site warmth (2406)	70	0	0.0%
1579	Saline slide agglutination test, positive (2698)	70	36	51.4%
1580	Paraesthesia (1674)	69	3	4.3%
1581	Eardrum rupture (2387)	69	3	4.3%
1582	Central vestibular disorder (2471)	69	14	20.3%
1583	Biliary sludge (2626)	69	18	26.1%
1584	Haemothorax (889)	68	61	89.7%
1585	Elevated lactic acid dehydrogenase (LDH) (2269)	68	24	35.3%
1586	Hypopigmentation (915)	68	3	4.4%
1587	Stomach inflammation (1798)	68	14	20.6%
1588	Device failure (93036)	68	4	5.9%
1589	Chewing disorder (2449)	68	8	11.8%
1590	Myocarditis (215)	67	58	86.6%
1591	Panleucopenia (169)	67	25	37.3%
1592	INEFFECTIVE, ESTRUS INDUCTION (99954)	67	2	3.0%
1593	Prostate hypertrophy (2104)	67	13	19.4%
1594	Clumsy (2466)	67	4	6.0%
1595	Fluid from nose (2482)	67	29	43.3%
1596	Stenotic ear canal (2570)	67	5	7.5%
1597	Pasty stool (2438)	67	8	11.9%
1598	Application site burning sensation (2555)	67	0	0.0%
1599	Irregular pulse (2558)	67	14	20.9%
1600	Rhinitis (869)	66	12	18.2%
1601	Carcinoma NOS (2971)	66	30	45.5%
1602	Sexual disorder NOS (see 'Reproductive' for named sexual disorders) (138)	66	13	19.7%
1603	Abdominal cavity hernia (252)	66	20	30.3%
1604	Nasal dryness (1636)	66	2	3.0%
1605	Mixed Product Other (99958)	66	1	1.5%
1606	Device Complication NOS (93029)	66	2	3.0%
1607	Administration device NOS, leaking (93142)	66	0	0.0%
1608	Pharyngitis (280)	65	5	7.7%
1609	Laryngeal oedema (1574)	65	27	41.5%
1610	PR-PERITONEAL EFFUSION (99663)	65	59	90.8%
1611	Inversion of albumin/globulin ratio (2117)	65	16	24.6%
1612	Jaw pain (1949)	65	8	12.3%
1613	Hair standing on end (909)	65	6	9.2%
1614	PR-NEOPLASIA (99936)	65	45	69.2%
1615	Acne (905)	65	1	1.5%
1616	Profuse bleeding (178)	65	24	36.9%
1617	Swollen gum (1815)	65	7	10.8%
1618	Gut sounds decreased (2162)	65	17	26.2%
1619	Immune-mediated polyarthritis (2681)	65	12	18.5%
1620	Lacrimation (439)	64	0	0.0%
1621	Preputial discharge (799)	64	7	10.9%
1622	Snoring (2506)	64	11	17.2%
1623	Spherocytosis (2612)	64	20	31.3%
1624	DEATH-SLAUGHTERED (99942)	63	46	73.0%
1625	Circulatory disorder NOS (2161)	63	29	46.0%
1626	Monoparesis (paralysis of limb) (1617)	63	21	33.3%
1627	Application site serosanguinous discharge (33)	63	3	4.8%
1628	Hepatic lipidosis (steatosis) (2321)	63	39	61.9%
1629	Male reproductive tract disorder NOS (767)	62	6	9.7%
1630	Septic arthritis (1899)	62	27	43.5%
1631	Premature anaesthesia recovery (2278)	62	3	4.8%
1632	Dropper, Abnormal (99815)	62	0	0.0%
1633	Desquamation (942)	62	5	8.1%
1634	Pimples (935)	62	2	3.2%
1635	Hepatic tumour (506)	62	33	53.2%
1636	Nervous system disorder NOS (1642)	62	21	33.9%
1637	Interstitial nephritis (715)	62	57	91.9%
1638	Eyesight trouble (1231)	62	11	17.7%
1639	Gastric irritation (1488)	62	14	22.6%
1640	Claw / hoof / nail loss (1185)	62	9	14.5%
1641	NT - tumour (NOS) (2351)	62	20	32.3%
1642	Application site tingling (2193)	62	0	0.0%
1643	Lack of hair regrowth (2586)	62	3	4.8%
1644	Injection site thickening (2898)	62	1	1.6%
1645	Post ictal state (3106)	62	3	4.8%
1646	Gastrointestinal irritation (3070)	62	4	6.5%
1647	Retinal haemorrhage (467)	61	13	21.3%
1648	Intussusception (329)	61	27	44.3%
1649	Paraplegia (692)	61	26	42.6%
1650	Injection site numbness (1546)	61	1	1.6%
1651	Oral pain (1660)	61	8	13.1%
1652	Transient blindness (1850)	60	4	6.7%
1653	Foam in the trachea (875)	60	53	88.3%
1654	Heavy sweating (1519)	60	10	16.7%
1655	Skin thinning (2181)	60	9	15.0%
1656	Salivary gland disorder (2383)	60	6	10.0%
1657	Hypoaesthesia (1957)	59	7	11.9%
1658	Loss of smell (1592)	59	11	18.6%
1659	Hyposensitivity to pain (1968)	59	27	45.8%
1660	Injection site fibrosis (2008)	59	1	1.7%
1661	Optic nerve disorder (450)	59	9	15.3%
1662	Tingling skin (1842)	59	0	0.0%
1663	Mewing (131)	59	4	6.8%
1664	Low free thyroxine (FT4) (2705)	59	7	11.9%
1665	Off food (2740)	59	15	25.4%
1666	PR-BONE MARROW, LESION(S) (99593)	58	45	77.6%
1667	Muscle degeneration (1119)	58	26	44.8%
1668	Ocular burn (1240)	58	0	0.0%
1669	Painful urination (2099)	58	12	20.7%
1670	Heart block 2nd degree (2432)	58	7	12.1%
1671	Pharyngeal oedema (1224)	57	18	31.6%
1672	PR-ADRENAL(S), LESION(S) (99588)	57	57	100.0%
1673	Atrial fibrillation (187)	57	17	29.8%
1674	Lack of efficacy (bacteria) - Mannheimia haemolytica (2995)	57	51	89.5%
1675	Leucocytosis (163)	57	10	17.5%
1676	Rectal haemorrhage (271)	57	28	49.1%
1677	Eyelid lump (2461)	57	4	7.0%
1678	Small intestinal bacterial overgrowth (2565)	57	4	7.0%
1679	Epistaxis (unilateral) (2485)	57	6	10.5%
1680	PR-COLON, LESION(S) (99607)	56	48	85.7%
1681	Abnormal oestrus NOS (1162)	56	4	7.1%
1682	Pinnal haemorrhage (359)	56	12	21.4%
1683	Taste alteration (1823)	56	0	0.0%
1684	Abdominal oedema (1063)	56	24	42.9%
1685	High leg gait (661)	56	4	7.1%
1686	Stomach cramp (1797)	56	3	5.4%
1687	Uterine disorder NOS (2146)	56	12	21.4%
1688	Indigestion (1536)	56	5	8.9%
1689	Ringworm (1733)	56	4	7.1%
1690	Oral abscess (2012)	55	10	18.2%
1691	Central nervous system depression (628)	55	24	43.6%
1692	Oral haemorrhage (296)	55	29	52.7%
1693	Insert, Abnormal (99975)	55	1	1.8%
1694	Elevated red cell distribution width (RDW) (2857)	55	20	36.4%
1695	Watery diarrhoea (3162)	55	5	9.1%
1696	INEFFECTIVE, COGNITIVE DYSFUNC (99092)	54	0	0.0%
1697	Exophthalmia (451)	54	16	29.6%
1698	Milk drop (534)	54	17	31.5%
1699	Acute mastitis (525)	54	44	81.5%
1700	Arthropathy NOS (1335)	54	14	25.9%
1701	Vocalizing while sleeping (2505)	54	8	14.8%
1702	Hypovolaemic shock (2675)	54	28	51.9%
1703	TOXICITY (99359)	53	33	62.3%
1704	INEFFECTIVE, SEIZURES (99146)	53	5	9.4%
1705	Lens opacity (443)	53	7	13.2%
1706	NT - fibrinous (broncho) pneumonia/fibrinous pleuropneumonia (2298)	53	53	100.0%
1707	Nasal irritation (1637)	53	2	3.8%
1708	Low vision (1598)	53	4	7.5%
1709	Salivary staining (2542)	53	3	5.7%
1710	Decreased skin turgor (2549)	53	15	28.3%
1711	Bloody foam in mouth and nose (2537)	53	45	84.9%
1712	IGA Animal morbidity greater than expected (93103)	53	47	88.7%
1713	Footpad disorder NOS (2880)	53	5	9.4%
1714	Easily startled (3061)	53	4	7.5%
1715	Injection site haemorrhage (82)	52	15	28.8%
1716	Sight affected (408)	52	11	21.2%
1717	Hypersensitivity to pain (703)	52	5	9.6%
1718	Intestinal haemorrhage (1083)	52	40	76.9%
1719	Sick euthyroid syndrome (2507)	52	15	28.8%
1720	Decreased intra-ocular pressure (2463)	52	6	11.5%
1721	Medical device replacement (93043)	52	4	7.7%
1722	Impurity (93154)	52	0	0.0%
1723	Hypertonia (1529)	51	13	25.5%
1724	Mucocutaneous ulcer (1920)	51	14	27.5%
1725	Prostate hyperplasia (793)	51	12	23.5%
1726	Dystocia (777)	51	22	43.1%
1727	Surgical site haemorrhage (2280)	51	15	29.4%
1728	Chest discomfort NOS (1263)	51	0	0.0%
1729	Drug administration duration too short (99818)	51	2	3.9%
1730	Pulmonary fibrosis (2259)	51	41	80.4%
1731	Submandibular oedema (2276)	51	8	15.7%
1732	Oedematous erythema (1655)	51	2	3.9%
1733	Application site scar (2518)	51	1	2.0%
1734	Valvular disorder (217)	50	21	42.0%
1735	Lymphadenitis (173)	50	14	28.0%
1736	Application site papule (2195)	50	0	0.0%
1737	Eyeball protrusion (456)	50	5	10.0%
1738	Peripheral neuropathy (1689)	50	11	22.0%
1739	Device-related infection (93037)	50	5	10.0%
1740	Systemic fungal infection (2550)	50	17	34.0%
1741	Bounding pulse (2522)	50	21	42.0%
1742	Quadriplegia (694)	49	24	49.0%
1743	Thoracic pain (1265)	49	8	16.3%
1744	INEFFECTIVE, STRONGYLOIDS (99152)	49	3	6.1%
1745	Tracheal obstruction (880)	49	19	38.8%
1746	Hepatic fibrosis (488)	49	36	73.5%
1747	Pinnal ulcer (2620)	49	1	2.0%
1748	Respiratory failure (1167)	49	42	85.7%
1749	Visual field defect (1871)	49	10	20.4%
1750	Entropion (425)	49	2	4.1%
1751	Nerve damage NOS (1639)	49	8	16.3%
1752	Walking slowly (3228)	49	7	14.3%
1753	Infarction (211)	48	37	77.1%
1754	PR-BLADDER, LESION(S) (99590)	48	42	87.5%
1755	Skin vascular disorder NOS (973)	48	5	10.4%
1756	Application site abscess (2004)	48	3	6.3%
1757	Spindle cell tumour (924)	48	12	25.0%
1758	Neurological pain NOS (1647)	48	9	18.8%
1759	Brain damage NOS (629)	48	31	64.6%
1760	Metastatic tumour (1927)	48	32	66.7%
1761	Pneumonitis (2258)	48	17	35.4%
1762	Product packaging confusion (93082)	48	2	4.2%
1763	Abnormal echocardiogram (2850)	48	8	16.7%
1764	Lack of efficacy (bacteria) - Histophilus somni (2993)	48	42	87.5%
1765	Brain tumour (3105)	48	35	72.9%
1766	PR-MULTIPLE SITES, BLOOD (99643)	47	47	100.0%
1767	ANISOCYTOSIS (99332)	47	11	23.4%
1768	Abnormal number of offspring (1912)	47	6	12.8%
1769	Exocrine pancreatic insufficiency (1940)	47	9	19.1%
1770	Keratoconjunctivitis (470)	47	5	10.6%
1771	Wrong patient received medication (99864)	47	3	6.4%
1772	Hepatic toxicosis (492)	47	22	46.8%
1773	Blood in trachea (878)	47	33	70.2%
1774	Sniffing (870)	47	0	0.0%
1775	Gall stone (1487)	47	7	14.9%
1776	ALBUMIN/GLOBULIN RATIO LO, BLD (99164)	47	6	12.8%
1777	Tic(s) (685)	47	2	4.3%
1778	Mouth blister (1622)	47	3	6.4%
1779	Hypovolaemia (2614)	47	21	44.7%
1780	Reduced faecal output (2678)	47	3	6.4%
1781	Nervousness (1644)	46	0	0.0%
1782	PR-PERITONEUM, LESION(S) (99664)	46	44	95.7%
1783	Spleen rupture (183)	46	38	82.6%
1784	Rale (852)	46	20	43.5%
1785	Gingival erythema (2442)	46	5	10.9%
1786	NT - endocardiosis (2308)	46	45	97.8%
1787	Organ haemorrhage (2098)	46	39	84.8%
1788	Sinus congestion (1749)	46	11	23.9%
1789	Conjunctival irritation (1394)	46	1	2.2%
1790	Barbering (2838)	46	0	0.0%
1791	Buccal irritation (299)	45	4	8.9%
1792	Pulmonary emphysema (845)	45	44	97.8%
1793	Lacrimation increased (1572)	45	1	2.2%
1794	Flaccid paralysis (695)	45	14	31.1%
1795	Tongue inflammation (288)	45	6	13.3%
1796	Chest tightness (1376)	45	0	0.0%
1797	Poor peripheral circulation (1702)	45	35	77.8%
1798	Palpitation (1670)	45	8	17.8%
1799	Neck writhing (2546)	45	7	15.6%
1800	Application site discharge NOS (3051)	45	0	0.0%
1801	PR-HEARTWORM DISEASE (99620)	44	44	100.0%
1802	Mammary hyperplasia (530)	44	2	4.5%
1803	Diabetes insipidus (401)	44	8	18.2%
1804	Eye stinging (1460)	44	0	0.0%
1805	Hepatic failure (497)	44	34	77.3%
1806	Flaccid muscles (2250)	44	13	29.5%
1807	Administration device NOS, breakage (93150)	44	0	0.0%
1808	Limb amputation (2896)	44	1	2.3%
1809	Lack of efficacy (endoparasite) - trematode (2659)	43	14	32.6%
1810	INEFFECTIVE, PINWORMS (99136)	43	1	2.3%
1811	PR-MULTIPLE SITES, CONGESTION (99646)	43	43	100.0%
1812	INEFFECTIVE, STOMACH WORM NOS (99149)	43	13	30.2%
1813	POLYCHROMASIA (99337)	43	13	30.2%
1814	Intestinal congestion (326)	43	31	72.1%
1815	Perineal fistula (255)	43	3	7.0%
1816	Elevated AST (2049)	43	10	23.3%
1817	Muscle necrosis (1245)	43	33	76.7%
1818	Reduced growth rate (2188)	43	19	44.2%
1819	Otitis interna (376)	43	4	9.3%
1820	Application site numbness (2192)	43	0	0.0%
1821	Lung collapse (2483)	43	27	62.8%
1822	Lack of efficacy (bacteria) - Rickettsia (3133)	43	1	2.3%
1823	Digestive tract stasis (308)	42	14	33.3%
1824	PR-MUSCLE(S), LESION(S) (99654)	42	38	90.5%
1825	Cholecystitis (479)	42	17	40.5%
1826	Pink eye (2016)	42	12	28.6%
1827	Oral discomfort (1657)	42	5	11.9%
1828	Cutaneous emphysema (1202)	42	17	40.5%
1829	Faecal impaction (266)	42	14	33.3%
1830	Prostatitis (2135)	42	6	14.3%
1831	Peritoneal haemorrhage (2101)	42	35	83.3%
1832	Allergy to food (1308)	42	1	2.4%
1833	Elevated SDMA (Symmetrical dimethylarginine) (2583)	42	10	23.8%
1834	Lack of efficacy (mite) (2652)	42	0	0.0%
1835	Lack of efficacy (protozoa) - Piroplasma (2809)	42	21	50.0%
1836	Asystole (2840)	42	34	81.0%
1837	Sinusitis (872)	41	12	29.3%
1838	Hydrocephalus (641)	41	29	70.7%
1839	Pemphigus (509)	41	4	9.8%
1840	Loss of strength (1594)	41	9	22.0%
1841	Lack of efficacy (endoparasite) - strongylids (2825)	41	3	7.3%
1842	Loss of egg quantity (745)	40	9	22.5%
1843	Anxious state of mind (1319)	40	0	0.0%
1844	Direct Coombs test, positive (2697)	40	15	37.5%
1845	Wrong drug administered (99863)	40	5	12.5%
1846	Myoclonus (650)	40	7	17.5%
1847	Pericardial haemorrhage (238)	40	38	95.0%
1848	Scour (303)	40	22	55.0%
1849	Hepatic encephalopathy (486)	40	21	52.5%
1850	Endocrine neoplasm (386)	40	19	47.5%
1851	Paraphimosis (797)	40	6	15.0%
1852	Semi-conscious (1738)	40	14	35.0%
1853	Respiratory discomfort (1258)	40	21	52.5%
1854	Acute (interstitial) pneumonia/pleuropneumonia (2295)	40	31	77.5%
1855	Premature birth (786)	39	17	43.6%
1856	INEFFECTIVE, ABORTION (99080)	39	12	30.8%
1857	CAT SCAN ABNORMAL (99216)	39	11	28.2%
1858	Cardiopathy (1061)	39	24	61.5%
1859	Focusing difficult (1479)	39	2	5.1%
1860	Cutaneous necrosis (1203)	39	14	35.9%
1861	Pituitary disorder NOS (402)	39	18	46.2%
1862	Persistent infection (1897)	39	11	28.2%
1863	Vulvar oedema (2121)	39	1	2.6%
1864	High thyroid stimulating hormone (TSH) (2703)	39	2	5.1%
1865	Adaptor, missing (93134)	39	0	0.0%
1866	Adrenal gland tumour (2927)	39	20	51.3%
1867	Hypernatraemia (2511)	39	6	15.4%
1868	Intestinal torsion (1067)	38	25	65.8%
1869	Liver fibrosis (490)	38	27	71.1%
1870	Duodenitis (325)	38	23	60.5%
1871	Multiple organ haemorrhage (2097)	38	38	100.0%
1872	Muscle inflammation (613)	38	5	13.2%
1873	Tail paralysis (2170)	38	9	23.7%
1874	Necrotizing pancreatitis (1893)	38	31	81.6%
1875	Joint cartilage disorder NOS (2243)	38	7	18.4%
1876	Medical device removal (93042)	38	0	0.0%
1877	Disturbance in attention (1420)	38	3	7.9%
1878	Oral erythema (2445)	38	0	0.0%
1879	Unable to chew (2451)	38	4	10.5%
1880	Giant platelets (2424)	38	8	21.1%
1881	High adrenocorticotropic (ACTH) hormone (2716)	38	0	0.0%
1882	Extra dose(s) administered (93080)	38	2	5.3%
1883	Conjunctival reddening (2830)	38	4	10.5%
1884	Lack of efficacy (bacteria) - Anaplasma NOS (2991)	38	0	0.0%
1885	Lack of efficacy (bacteria) - Bordetella (3013)	38	3	7.9%
1886	Clenched jaw (3101)	38	5	13.2%
1887	CARBON DIOXIDE HIGH, BLOOD (99229)	37	14	37.8%
1888	Eczema (934)	37	0	0.0%
1889	Endocarditis (210)	37	35	94.6%
1890	Pharyngeal disorder (279)	37	9	24.3%
1891	Tongue necrosis (1980)	37	14	37.8%
1892	Scrotal oedema (804)	37	7	18.9%
1893	Pleuritis (892)	37	36	97.3%
1894	Pinnal necrosis (362)	37	4	10.8%
1895	Cartilage degeneration (579)	37	9	24.3%
1896	Organ petechiae (2087)	37	34	91.9%
1897	Drug label incomplete (99969)	37	0	0.0%
1898	Myasthenia gravis (1142)	37	9	24.3%
1899	Blistering of mouth (1348)	37	2	5.4%
1900	Cleft palate (2078)	37	24	64.9%
1901	Dysorexia (2271)	37	1	2.7%
1902	Depigmentation of nasal plane (2177)	37	2	5.4%
1903	Lack of efficacy (endoparasite) - Trichostrongylus (2794)	37	6	16.2%
1904	Lung nodule NOS (3122)	37	23	62.2%
1905	PR-PLEURAL EFFUSION (99668)	36	30	83.3%
1906	Blood dyscrasia NOS (1058)	36	16	44.4%
1907	Abnormal birth weight (1911)	36	15	41.7%
1908	Joint oedema (572)	36	8	22.2%
1909	Tendon injury (626)	36	2	5.6%
1910	Intestinal occlusion (2095)	36	12	33.3%
1911	Contact dermatitis (1396)	36	0	0.0%
1912	Suppurative dermatitis (2494)	36	7	19.4%
1913	Wrong drug dispensed (93078)	36	3	8.3%
1914	Lack of efficacy (endoparasite) - Cooperia (2795)	36	2	5.6%
1915	Adaptor, leaking (93151)	36	0	0.0%
1916	Low amylase (3194)	36	10	27.8%
1917	CARBON DIOXIDE LOW, BLOOD (99231)	35	15	42.9%
1918	Other metabolic disorder (1668)	35	9	25.7%
1919	Cerebral oedema (635)	35	27	77.1%
1920	Injection site joint reaction (1543)	35	1	2.9%
1921	Loss of voice (1267)	35	10	28.6%
1922	Pneumothorax (2035)	35	21	60.0%
1923	Gastric torsion (338)	35	25	71.4%
1924	Skin fibrosarcoma (916)	35	6	17.1%
1925	Comedo/blackhead (2382)	35	3	8.6%
1926	Lymphoedema (2319)	35	9	25.7%
1927	Encephalopathy NOS (666)	34	22	64.7%
1928	PR-THYMUS, LESION(S) (99687)	34	34	100.0%
1929	Valvular insufficiency (218)	34	9	26.5%
1930	Tonic seizure (1126)	34	9	26.5%
1931	Product tampering (93009)	34	1	2.9%
1932	Attractiveness to males (2061)	34	3	8.8%
1933	Eyelid mass NOS (2829)	34	1	2.9%
1934	Feeling depressed (1404)	33	0	0.0%
1935	Displaced abomasum (323)	33	19	57.6%
1936	Synovial fluid, abnormal NOS (2721)	33	3	9.1%
1937	Burning mouth sensation (1366)	33	0	0.0%
1938	Wobbler (709)	33	8	24.2%
1939	Scrotal disorder NOS (802)	33	11	33.3%
1940	Taste disorder (1824)	33	0	0.0%
1941	Heart insufficiency (200)	33	10	30.3%
1942	Myopathy (610)	33	11	33.3%
1943	Liver abscess (485)	33	22	66.7%
1944	Decreased number of spermatozoa (2129)	33	2	6.1%
1945	Pancreas endocrine disorder NOS (396)	33	18	54.5%
1946	Increased reflexes (1532)	33	9	27.3%
1947	Heart block 3rd degree (2433)	33	9	27.3%
1948	Abnormal dexamethasone suppression test (2662)	33	7	21.2%
1949	High trypsin-like immunoreactivity (TLI) (2693)	33	4	12.1%
1950	Hypertrophic concentric cardiomyopathy (2301)	33	23	69.7%
1951	Dysmetria (1137)	32	6	18.8%
1952	ANION GAP HI, BLD (99188)	32	10	31.3%
1953	Injection site neoplasm NOS (1879)	32	11	34.4%
1954	Injection site tingling (1555)	32	0	0.0%
1955	Convulsive disorder NOS (1397)	32	1	3.1%
1956	Stinging skin (1796)	32	0	0.0%
1957	Copper toxicity signs (554)	32	9	28.1%
1958	Application site haemorrhage (11)	32	1	3.1%
1959	Miscarriage (1616)	32	0	0.0%
1960	NT - acute (interstitial) pneumonia/pleuropneumonia (2295)	32	24	75.0%
1961	Hypertrichosis (2180)	32	1	3.1%
1962	Injury associated with device (93041)	32	5	15.6%
1963	Fish body deformity (987)	32	30	93.8%
1964	Elevated insulin (2545)	32	2	6.3%
1965	Increased skin temperature (2691)	32	2	6.3%
1966	Immune-mediated polyarthropathy (2682)	32	4	12.5%
1967	Upper respiratory sounds (3119)	32	10	31.3%
1968	Oesophagus obstruction (277)	31	8	25.8%
1969	PLATELETS, ABNORMAL (99305)	31	11	35.5%
1970	BILE ACIDS ABNORMAL, BLOOD (99193)	31	5	16.1%
1971	Perinatal mortality NOS (783)	31	26	83.9%
1972	ALBUMIN HIGH, URINE (99174)	31	3	9.7%
1973	Vaginal prolapse (819)	31	14	45.2%
1974	Portacaval shunt (504)	31	4	12.9%
1975	Clonic seizure (1125)	31	4	12.9%
1976	Throat pain (1837)	31	1	3.2%
1977	Eye neoplasm (1987)	31	8	25.8%
1978	NT - chronic interstitial nephritis (2360)	31	31	100.0%
1979	ABNORMAL TEST RESULT, THYROID NOS (93018)	31	5	16.1%
1980	Hepatic vascular disorder (502)	31	10	32.3%
1981	Spasticity (701)	31	6	19.4%
1982	Ureteric disorder (724)	31	11	35.5%
1983	NT - hepatic lipidosis (steatosis) (2321)	31	28	90.3%
1984	Tendon rupture (627)	31	3	9.7%
1985	Thickened ear canal(s) (2456)	31	2	6.5%
1986	Epistaxis (bilateral) (2484)	31	10	32.3%
1987	Head shy (2413)	31	6	19.4%
1988	Pulmonary metastases (2369)	31	24	77.4%
1989	Intestinal thickening (3159)	31	6	19.4%
1990	PR-BLOOD VESSEL(S), LESION(S) (99591)	30	24	80.0%
1991	Premature parturition (787)	30	10	33.3%
1992	Abnormal spermatozoa NOS (763)	30	0	0.0%
1993	Atelectasis (2749)	30	23	76.7%
1994	Bone marrow suppression (150)	30	13	43.3%
1995	Pseudopregnancy (766)	30	4	13.3%
1996	Poor feed conversion (1047)	30	11	36.7%
1997	Photosensitivity (955)	30	2	6.7%
1998	Congenital musculo-skeletal disorder (597)	30	12	40.0%
1999	Tongue paraesthesia (1250)	30	0	0.0%
2000	Implant site abscess (36)	30	7	23.3%
2001	Mucus in trachea (881)	30	8	26.7%
2002	Heat stroke (2504)	30	18	60.0%
2003	Increased testicle size (2068)	30	3	10.0%
2004	Osteomyelitis (592)	30	6	20.0%
2005	Inflamed mucosae (1004)	30	2	6.7%
2006	Nerve pain NOS (1640)	30	3	10.0%
2007	Ear canal oedema (2569)	30	2	6.7%
2008	Peripheral vestibular disorder (2457)	30	3	10.0%
2009	Chronic kidney disease (3213)	30	6	20.0%
2010	Application site moist eczema (2065)	29	1	3.4%
2011	Pericarditis (216)	29	25	86.2%
2012	Obstructive airway cough (883)	29	5	17.2%
2013	Blue eye (414)	29	6	20.7%
2014	Liver degeneration (2120)	29	20	69.0%
2015	Enteric pathogen NOS (2564)	29	6	20.7%
2016	Generalised skin slough (943)	29	2	6.9%
2017	Lack of efficacy (bacteria) - E.coli (2786)	29	16	55.2%
2018	Lack of efficacy (protozoa) - Cytauxzoon feli (3134)	29	14	48.3%
2019	BILIRUBIN(DIRECT) HIGH, BLOOD (99196)	28	10	35.7%
2020	Emphysema NOS (see 'Respiratory' for pulmonary emphysema) (1010)	28	20	71.4%
2021	PR-MOUTH/LIP(S), LESION(S) (99640)	28	7	25.0%
2022	Sinus disorder NOS (1750)	28	4	14.3%
2023	Application site bruising (8)	28	0	0.0%
2024	Lip paralysis (1151)	28	2	7.1%
2025	Goose stepping (663)	28	5	17.9%
2026	Absence seizure (1295)	28	3	10.7%
2027	Parathyroid disorder NOS (399)	28	13	46.4%
2028	Cholangitis (477)	28	10	35.7%
2029	Measuring or administration device error NOS (93091)	28	2	7.1%
2030	Tympanic opacity (2623)	28	0	0.0%
2031	Lack of efficacy (endoparasite) - Ostertagia/Teladorsagia (2799)	28	5	17.9%
2032	Lack of efficacy (virus) - bovine viral diarrhoea virus (2812)	28	25	89.3%
2033	Inhaler, malfunction (93136)	28	0	0.0%
2034	Generalised congestion NOS (3137)	28	5	17.9%
2035	PR-GASTROINTESTINAL PARASITISM (99617)	27	20	74.1%
2036	Aplastic anaemia (146)	27	15	55.6%
2037	PR-THYROID, LESION(S) (99688)	27	24	88.9%
2038	Generalised inflammation of eye (459)	27	4	14.8%
2039	Intercepted drug dispensing error (99840)	27	0	0.0%
2040	Prostatic tumour (794)	27	16	59.3%
2041	Residues NOS (2044)	27	5	18.5%
2042	Abortion spontaneous (1294)	27	4	14.8%
2043	Respiratory tract neoplasm NOS (888)	27	15	55.6%
2044	Sore mouth (1782)	27	7	25.9%
2045	Decubitus (2024)	27	7	25.9%
2046	Cyanotic spots/blotchy skin (2497)	27	4	14.8%
2047	Elevated C-reactive protein (2267)	27	7	25.9%
2048	Cyst rupture NOS (2885)	27	4	14.8%
2049	Hypertrophic dilated cardiomyopathy (2302)	27	15	55.6%
2050	Swelling around eye (see also Immune system disorders) (461)	27	0	0.0%
2051	PR-TRACHEA, LESION(S) (99690)	26	26	100.0%
2052	Lacrimal disorder NOS (441)	26	5	19.2%
2053	Metritis (807)	26	9	34.6%
2054	Wrong information typed on label (99979)	26	1	3.8%
2055	Haemorrhagic gastritis (1093)	26	11	42.3%
2056	Dermoid cyst (1407)	26	2	7.7%
2057	PR-DUODENUM, LESION(S) (99674)	26	15	57.7%
2058	Implant site swelling (56)	26	1	3.8%
2059	Penile erection (2136)	26	2	7.7%
2060	Cushings disease - pituitary dependent (381)	26	3	11.5%
2061	Iron deficiency anaemia (144)	26	4	15.4%
2062	Rubra (947)	26	0	0.0%
2063	Feet shifting (2547)	26	4	15.4%
2064	Pleural fluid, abnormal NOS (2720)	26	20	76.9%
2065	Luminal enteropathy (2332)	26	7	26.9%
2066	HCO3 LOW, BLOOD (99262)	25	10	40.0%
2067	Uraemia (722)	25	19	76.0%
2068	Skin emphysema (1201)	25	8	32.0%
2069	Hyperaemic mucosae (1005)	25	6	24.0%
2070	Buccal ulceration (298)	25	4	16.0%
2071	Abnormal behaviour NOS (1291)	25	0	0.0%
2072	Labelled drug-disease interaction medication error (99841)	25	8	32.0%
2073	Pregnancy (785)	25	7	28.0%
2074	T4 LOW, SERUM (93014)	25	6	24.0%
2075	Dizzy spell (1424)	25	0	0.0%
2076	Lens luxation (447)	25	2	8.0%
2077	Lack of efficacy (ectoparasite) - fly (2650)	25	0	0.0%
2078	Elevated serum lipids (2667)	25	1	4.0%
2079	Snorting (2775)	25	5	20.0%
2080	PR-PLEURA, LESION(S) (99667)	24	24	100.0%
2081	INEFFECTIVE, GRUBS (99111)	24	1	4.2%
2082	PR-BONE(S), LESION(S) (99594)	24	16	66.7%
2083	PR-TONGUE, LESION(S) (99689)	24	14	58.3%
2084	Vitamin disorder (551)	24	4	16.7%
2085	Phlebitis (241)	24	3	12.5%
2086	Retained placenta (788)	24	4	16.7%
2087	Cardiac tamponade (236)	24	20	83.3%
2088	Tongue paralysis (2108)	24	8	33.3%
2089	Smell disorder NOS (1777)	24	2	8.3%
2090	Malformation NOS (1164)	24	7	29.2%
2091	NT - hypertrophic concentric cardiomyopathy (2301)	24	22	91.7%
2092	Application site paraesthesia (2112)	24	0	0.0%
2093	Injection site skin scaling (2203)	24	1	4.2%
2094	Tendinitis (625)	24	2	8.3%
2095	Walking on tiptoes (2389)	24	4	16.7%
2096	Preputial swelling (2535)	24	2	8.3%
2097	INGREDIENT QUALITY ISSUE NOS (93097)	24	1	4.2%
2098	Lack of efficacy (endoparasite) - Haemonchus (2797)	24	8	33.3%
2099	Acute pancreatitis (3072)	24	10	41.7%
2100	Renal infarcts (2366)	24	20	83.3%
2101	Eyelid ptosis - neurologic (see also Drooping eyelid NOS) (2392)	24	3	12.5%
2102	Anal oedema (2239)	23	1	4.3%
2103	Cervical spondylopathy (708)	23	3	13.0%
2104	CORTISOL:CREATININE HI, URINE (99234)	23	1	4.3%
2105	Injection site blister (75)	23	2	8.7%
2106	Polyarthropathy (1118)	23	5	21.7%
2107	Tonic muscle spasm (1140)	23	8	34.8%
2108	Ear flap haemorrhage (352)	23	1	4.3%
2109	Lack of heat (757)	23	1	4.3%
2110	Omentum inflammation (254)	23	13	56.5%
2111	Swollen gland (1814)	23	2	8.7%
2112	Lump (1191)	23	1	4.3%
2113	Hepatic cirrhosis (489)	23	15	65.2%
2114	Macular rash (1599)	23	0	0.0%
2115	Urinary tract bleeding (1965)	23	11	47.8%
2116	Boil (1355)	23	1	4.3%
2117	Vascular dilation and/or rupture (242)	23	9	39.1%
2118	Onset of lactation (2122)	23	3	13.0%
2119	Endocardiosis (2308)	23	22	95.7%
2120	Chewing at injection site (3053)	23	0	0.0%
2121	Bolus, Abnormal (99001)	22	2	9.1%
2122	Bone marrow aplasia (149)	22	13	59.1%
2123	PR-MENINGES, LESION(S) (99635)	22	22	100.0%
2124	CEREBROSPINAL FLUID ABNORMAL (99239)	22	6	27.3%
2125	Tonsillitis (2452)	22	3	13.6%
2126	Hemiplegia (693)	22	6	27.3%
2127	Founder (616)	22	6	27.3%
2128	Purpura (1714)	22	7	31.8%
2129	Implant site bleeding (47)	22	9	40.9%
2130	Implant, Damaged (99973)	22	0	0.0%
2131	Haemorrhagic bladder (730)	22	11	50.0%
2132	Spondylitis (2244)	22	4	18.2%
2133	Lacrimation decreased (442)	22	1	4.5%
2134	Hypersthenuria (2477)	22	6	27.3%
2135	Juvenile cellulitis (puppy strangles) (2491)	22	1	4.5%
2136	Adenocarcinoma NOS (2352)	22	12	54.5%
2137	Nose swelling (3016)	22	0	0.0%
2138	PR-SPINAL CORD, LESION(S) (99678)	21	20	95.2%
2139	External teat disorder (537)	21	4	19.0%
2140	Photosensitization (956)	21	5	23.8%
2141	Lymph node abscess (2060)	21	5	23.8%
2142	Right ventricular dilatation (203)	21	15	71.4%
2143	Heart disorder aggravated (199)	21	8	38.1%
2144	Hyperparathyroidism (397)	21	4	19.0%
2145	Deterioration of muscle function (1409)	21	11	52.4%
2146	Sensory loss (1741)	21	4	19.0%
2147	NT - lymphoplasmacytic enteritis (2339)	21	17	81.0%
2148	Vulvovaginitis (824)	21	0	0.0%
2149	Vacant (2636)	21	3	14.3%
2150	Kidney atrophy (2984)	21	11	52.4%
2151	Tympanic discoloration (2622)	21	0	0.0%
2152	Lack of heart sounds on auscultation (2839)	21	13	61.9%
2153	Swollen eye (see also Immune system disorders) (1810)	21	0	0.0%
2154	Chewing - pruritus (2618)	21	0	0.0%
2155	PR-MESENTERY, LESION(S) (99637)	20	19	95.0%
2156	Glossitis (289)	20	5	25.0%
2157	Agalactia (531)	20	6	30.0%
2158	Cirrhosis (487)	20	8	40.0%
2159	Myoglobinuria (2056)	20	8	40.0%
2160	Injection site gaseous gangrene (2094)	20	17	85.0%
2161	Clonic muscle spasm (1139)	20	2	10.0%
2162	Dermatophytosis (1406)	20	0	0.0%
2163	Sticky eye (1791)	20	3	15.0%
2164	Male reproductive tract neoplasm NOS (768)	20	5	25.0%
2165	Peripheral vascular disorder (1690)	20	4	20.0%
2166	Hypoparathyroidism (398)	20	2	10.0%
2167	NT - chronic (broncho)pneumonia/pleuropneumonia (2296)	20	19	95.0%
2168	Oral mucosal blistering (1659)	20	0	0.0%
2169	Application site skin squamosis (2199)	20	1	5.0%
2170	Implant site infection (2201)	20	1	5.0%
2171	Trace element disorder (549)	20	17	85.0%
2172	Application site pigmentation disorders (2517)	20	0	0.0%
2173	Fibrinous (broncho) pneumonia/fibrinous pleuropneumonia (2298)	20	20	100.0%
2174	Enophthalmos (see also Sunken eyes in Systemic disorders) (2761)	20	5	25.0%
2175	Stertor (3118)	20	10	50.0%
2176	PR-CEREBRUM, LESION(S) (99604)	19	18	94.7%
2177	Ruminant stomach disorder (1230)	19	13	68.4%
2178	PR-EYE(S)/LID(S), LESION(S) (99612)	19	11	57.9%
2179	INEFFECTIVE, BOTS (99091)	19	0	0.0%
2180	Amaurosis (see also PT Impaired vision) (410)	19	5	26.3%
2181	Metabolism and nutrition disorder NOS (2019)	19	9	47.4%
2182	Anhidrosis (1316)	19	0	0.0%
2183	Hydrothorax (890)	19	15	78.9%
2184	Hyperkalemic condition (1944)	19	7	36.8%
2185	Pimple (1696)	19	0	0.0%
2186	Tumbling circling disease (see also ataxia at 'Neurological') (370)	19	2	10.5%
2187	Cholelithiasis (1377)	19	5	26.3%
2188	Unilateral paresis (1154)	19	4	21.1%
2189	NT - suppurative (broncho) pneumonia/pleuropneumonia (2300)	19	19	100.0%
2190	Trigeminus paralysis (1149)	19	3	15.8%
2191	NT - adenocarcinoma (2352)	19	9	47.4%
2192	Fanconi syndrome (2125)	19	2	10.5%
2193	Otic haematoma (351)	19	0	0.0%
2194	High free thyroxine (FT4) (2704)	19	3	15.8%
2195	Adaptor, damaged (93132)	19	0	0.0%
2196	Cramp NOS (2841)	19	1	5.3%
2197	Polyarthropathy NOS (see also PT Immune-mediated polyarthropathy) (1118)	19	3	15.8%
2198	Lack of efficacy (bacteria) - Pasteurella multocida (2997)	19	15	78.9%
2199	Low liver enzymes NOS (2689)	19	3	15.8%
2200	UROBILINOGEN HIGH, URINE (99366)	18	6	33.3%
2201	PR-PARATHYROID, LESION(S) (99659)	18	16	88.9%
2202	Fit (643)	18	7	38.9%
2203	Hot flush (1924)	18	0	0.0%
2204	Necrotising steatitis (1037)	18	4	22.2%
2205	Endocrine system disorder NOS (2014)	18	2	11.1%
2206	Lateral neck deviation (596)	18	6	33.3%
2207	Retinal atrophy (462)	18	1	5.6%
2208	ALBUMIN/GLOBULIN RATIO HI, BLD (99162)	18	3	16.7%
2209	Discoloured teeth (282)	18	0	0.0%
2210	NT - suppurative peritonitis (2288)	18	16	88.9%
2211	Toxic epidermal necrolysis (1848)	18	5	27.8%
2212	Complication of diabetes (393)	18	5	27.8%
2213	Haemopoietic neoplasm NOS (170)	18	8	44.4%
2214	Hypokaleaemia (2418)	18	5	27.8%
2215	Leucopenia (164)	18	8	44.4%
2216	Eye paralysis (for Miosis etc see 'Neurological') (454)	18	2	11.1%
2217	Cognitive disturbance (1383)	18	5	27.8%
2218	NT - necrotic hepatitis (2326)	18	18	100.0%
2219	NT - hypertrophic dilated cardiomyopathy (2302)	18	14	77.8%
2220	Hypertrophic osteodystrophy (2124)	18	2	11.1%
2221	Wrong technique in device usage process (93027)	18	1	5.6%
2222	Bone marrow hypoplasia (2385)	18	6	33.3%
2223	Flehmen response (2532)	18	1	5.6%
2224	INEFFECTIVE, PARASITE(S) (99134)	18	2	11.1%
2225	Paradoxical vestibular syndrome (2472)	18	3	16.7%
2226	Product compounding error (93087)	18	4	22.2%
2227	Localised allergic oedema NOS (2767)	18	1	5.6%
2228	Lack of efficacy (virus) - coronavirus - NOS (2814)	18	9	50.0%
2229	Polyp (2878)	18	3	16.7%
2230	Persistent cough (2875)	18	4	22.2%
2231	Scleral haemorrhage (2831)	18	4	22.2%
2232	Application site skin slough (3046)	18	0	0.0%
2233	Smell alteration (1776)	17	1	5.9%
2234	Disorders of menstrual cycle NOS (1417)	17	0	0.0%
2235	Anoestrus (756)	17	0	0.0%
2236	Selenium deficiency syndrome (550)	17	15	88.2%
2237	Ovarian cyst (771)	17	1	5.9%
2238	Loss of egg quality (744)	17	1	5.9%
2239	Milk fever (559)	17	8	47.1%
2240	Cerebral vascular accident (638)	17	8	47.1%
2241	Gum bruising (1887)	17	5	29.4%
2242	Hydronephrosis (2066)	17	5	29.4%
2243	Oesophageal ulcer (1979)	17	12	70.6%
2244	NT - chronic (interstitial) pneumonia/pleuropneumonia (2297)	17	14	82.4%
2245	Perivascular dermatitis (2495)	17	0	0.0%
2246	Gingival swelling (2441)	17	4	23.5%
2247	Cardiac insufficiency (2160)	17	11	64.7%
2248	Bone nonunion, medical device (93031)	17	2	11.8%
2249	Complications of device insertion (93023)	17	1	5.9%
2250	Other coagulation investigation abnormality (152)	17	6	35.3%
2251	Male infertility NOS (2399)	17	0	0.0%
2252	Low liver enzymes (2689)	17	5	29.4%
2253	Hypercalcaemic condition (2687)	17	5	29.4%
2254	Lymphoplasmacytic enteritis (2339)	17	13	76.5%
2255	Pancreatic tumour NOS (2943)	17	12	70.6%
2256	AMMONIA INCREASED, BLOOD (99186)	16	8	50.0%
2257	Asphyxia (1916)	16	10	62.5%
2258	ERYTHROCYTOSIS (99307)	16	3	18.8%
2259	Congenital disorder NOS (2030)	16	6	37.5%
2260	Copper deficiency signs (561)	16	14	87.5%
2261	Cryptorchidism (754)	16	8	50.0%
2262	Intrauterine death (792)	16	12	75.0%
2263	Eye sore and red (1459)	16	2	12.5%
2264	Stinging sensation in eye (1795)	16	0	0.0%
2265	Vertigo (1865)	16	0	0.0%
2266	NT - renal infarcts (2366)	16	13	81.3%
2267	Hypoventilation (2058)	16	8	50.0%
2268	Respiratory tract irritation (1728)	16	0	0.0%
2269	Rattling chest (853)	16	7	43.8%
2270	Digestive tract malabsorption disorder NOS (324)	16	1	6.3%
2271	Preputial haemorrhage (1914)	16	6	37.5%
2272	Hypopyon (419)	16	2	12.5%
2273	Application site granuloma (7)	16	1	6.3%
2274	Tracheal bleeding (877)	16	14	87.5%
2275	Connective tissue disorder NOS (598)	16	3	18.8%
2276	Sterile (1790)	16	0	0.0%
2277	NT - necrohemorrhagic enteritis (2340)	16	12	75.0%
2278	Aural neoplasia NOS (353)	16	4	25.0%
2279	Foetal death (2134)	16	10	62.5%
2280	Intercepted drug administration error (99839)	16	0	0.0%
2281	Motor neurone disease (1621)	16	2	12.5%
2282	INEFFECTIVE, TRANQUILIZATION (99156)	16	5	31.3%
2283	Fasciitis (2467)	16	8	50.0%
2284	Implant site reaction NOS (64)	16	0	0.0%
2285	INEFFECTIVE, NEMATODES (99131)	16	2	12.5%
2286	Eye dryness (sensation) (2524)	16	0	0.0%
2287	Endotoxaemia (2595)	16	11	68.8%
2288	Abdominal transudate (2617)	16	7	43.8%
2289	Lack of efficacy (virus) - distemper virus (2551)	16	12	75.0%
2290	Abnormal rectal palpation (2683)	16	3	18.8%
2291	Foreign body (not GI) (2888)	16	3	18.8%
2292	PR-ASCITES (99662)	15	14	93.3%
2293	Burning sensation of the throat (1270)	15	0	0.0%
2294	Devitalisation (1046)	15	2	13.3%
2295	Milk production increase (536)	15	2	13.3%
2296	Pleural inflammation (891)	15	10	66.7%
2297	Sore eye (1781)	15	0	0.0%
2298	Reduced testicle size (2033)	15	6	40.0%
2299	Eye numbness (1235)	15	0	0.0%
2300	Ileitis (328)	15	11	73.3%
2301	Abomasal ulcer (1084)	15	15	100.0%
2302	Pyothorax (893)	15	11	73.3%
2303	INEFFECTIVE, OVULATION (99133)	15	0	0.0%
2304	Hyperpnoea (2138)	15	3	20.0%
2305	Eyelid ptosis (2392)	15	0	0.0%
2306	SERUM AMYLOID A HIGH, BLOOD (93045)	15	1	6.7%
2307	Conjunctival haemorrhage (2459)	15	3	20.0%
2308	Measuring or administration device difficult to use (93090)	15	0	0.0%
2309	Heart block 1st degree (2431)	15	2	13.3%
2310	Hiatus hernia (1524)	15	7	46.7%
2311	Product dosage form confusion (93083)	15	1	6.7%
2312	ENUCLEATION (93098)	15	5	33.3%
2313	Stability failure (93153)	15	0	0.0%
2314	Enlarged thyroid gland (2679)	15	5	33.3%
2315	Chronic hepatitis (2763)	15	4	26.7%
2316	Skin hyperplasia (2986)	15	2	13.3%
2317	Lack of efficacy (virus) - bovine respiratory syncytial virus (3003)	15	12	80.0%
2318	NEOPLASM RUPTURE (99940)	14	11	78.6%
2319	Nail discolouration (1632)	14	0	0.0%
2320	Sunburn (957)	14	3	21.4%
2321	INEFFECTIVE, KCS (99118)	14	0	0.0%
2322	Injection site pyoderma (99)	14	1	7.1%
2323	Cranial nerve paralysis (1150)	14	3	21.4%
2324	Chordae tendonae rupture (2428)	14	9	64.3%
2325	Bullous disorder NOS (1363)	14	0	0.0%
2326	Splenitis (184)	14	9	64.3%
2327	Chapped skin (1374)	14	2	14.3%
2328	Dyspepsia (1434)	14	4	28.6%
2329	Perinatal mortality (1686)	14	8	57.1%
2330	Physical label loose (99848)	14	0	0.0%
2331	NT - haemorrhagic enteritis (2337)	14	11	78.6%
2332	Lack of efficacy (endoparasite) - lungworm (3002)	14	0	0.0%
2333	Positive tracheal pinch (2585)	14	1	7.1%
2334	Increased culls (2513)	14	14	100.0%
2335	Medication monitoring error (93092)	14	0	0.0%
2336	Sheath oedema (2640)	14	1	7.1%
2337	Decreased ruminal activity (2619)	14	6	42.9%
2338	Rectal mass (2842)	14	4	28.6%
2339	Application site purulent discharge (3048)	14	2	14.3%
2340	Addisonian crisis (3075)	14	1	7.1%
2341	PR-ESOPHAGUS, LESION(S) (99611)	13	11	84.6%
2342	PR-PERICARDIAL EFFUSION (99661)	13	13	100.0%
2343	PR-BRONCHI, LESION(S) (99596)	13	13	100.0%
2344	Lack of efficacy (endoparasite) - Cyathostominae (2796)	13	2	15.4%
2345	PR-NERVE(S), LESION(S) (99655)	13	13	100.0%
2346	Hand and arm swollen (1510)	13	0	0.0%
2347	Application site rubra (6)	13	1	7.7%
2348	Wry neck (595)	13	4	30.8%
2349	Bullae (925)	13	3	23.1%
2350	Acute haemorrhagic pancreatitis (331)	13	11	84.6%
2351	Malignant hyperthermia (1013)	13	5	38.5%
2352	Palpebral oedema (420)	13	1	7.7%
2353	Arthrosis (575)	13	2	15.4%
2354	Paronychia (1682)	13	1	7.7%
2355	Injection site paraesthesia (1548)	13	0	0.0%
2356	Hepatic insufficiency (498)	13	3	23.1%
2357	Foetal resorption (781)	13	3	23.1%
2358	Hepatic jaundice (1278)	13	4	30.8%
2359	Arteritis (240)	13	10	76.9%
2360	Central nervous system infection NOS (1372)	13	2	15.4%
2361	Supraventricular and nodal arrhythmia (2221)	13	3	23.1%
2362	Acute jaundice (1297)	13	3	23.1%
2363	Hypotonia (2251)	13	4	30.8%
2364	Penile protrusion (2100)	13	2	15.4%
2365	Cerebellar ataxia (2634)	13	1	7.7%
2366	Low tri-iodothyronine (T3) (2712)	13	0	0.0%
2367	Low skin temperature (2744)	13	3	23.1%
2368	Suppurative (broncho) pneumonia/pleuropneumonia (2300)	13	13	100.0%
2369	Abnormal digital pulse (2867)	13	2	15.4%
2370	Application site mass NOS (2832)	13	2	15.4%
2371	Cardiac neoplasm NOS (2309)	13	10	76.9%
2372	Elevated serum amyloid A (SAA) (3179)	13	4	30.8%
2373	Periorbital oedema (see also Immune system disorders) (460)	13	0	0.0%
2374	BILIRUBIN(INDIRECT) HIGH, BLD (99197)	12	8	66.7%
2375	Placental abnormality (784)	12	7	58.3%
2376	Anal prolapse (256)	12	3	25.0%
2377	Agitated state of mind (1299)	12	1	8.3%
2378	Bronchial oedema (850)	12	7	58.3%
2379	Oral dryness (294)	12	2	16.7%
2380	Reduced sexual interest (see 'Reproductive' for named sexual disorders) (2029)	12	0	0.0%
2381	Difficulty sleeping (1412)	12	0	0.0%
2382	Migraine (1614)	12	0	0.0%
2383	Panic attack (1671)	12	0	0.0%
2384	Sclerotitis (474)	12	3	25.0%
2385	Scrotal irritation NOS (1737)	12	1	8.3%
2386	Airsacculitis (828)	12	7	58.3%
2387	Sore tongue (1783)	12	1	8.3%
2388	Spleen torsion (2106)	12	9	75.0%
2389	Thyroidititis (1839)	12	9	75.0%
2390	Increased intracranial pressure (634)	12	10	83.3%
2391	NT - eosinophilic enteritis (2334)	12	9	75.0%
2392	NT - lymphoma/ lymphadenomegaly (2350)	12	12	100.0%
2393	Toothache (1847)	12	2	16.7%
2394	Implant site inflammation (48)	12	0	0.0%
2395	Viral skin infection NOS (1869)	12	0	0.0%
2396	Rhinorrhoea (1729)	12	0	0.0%
2397	Lack of efficacy (parvovirus) (2552)	12	1	8.3%
2398	Lack of efficacy (virus) - parainfluenza (2822)	12	2	16.7%
2399	Error occurred in home (93171)	12	0	0.0%
2400	Digit amputation (1413)	12	0	0.0%
2401	Nasal ulceration (2985)	12	1	8.3%
2402	Heart base tumour NOS (2916)	12	6	50.0%
2403	Fibrosarcoma (2918)	12	0	0.0%
2404	Anal sac adenocarcioma (2977)	12	1	8.3%
2405	Priapism (801)	11	2	18.2%
2406	PR-MULTIPLE SITES (99653)	11	11	100.0%
2407	Insomnia (1557)	11	0	0.0%
2408	NEOPLASM BLEEDING (99938)	11	7	63.6%
2409	Laryngitis (876)	11	3	27.3%
2410	IRON LOW, BLOOD (99249)	11	4	36.4%
2411	Runt (790)	11	5	45.5%
2412	Bowel torsion (1068)	11	6	54.5%
2413	Heartburn (1516)	11	0	0.0%
2414	Feeling sick (1470)	11	0	0.0%
2415	Aortic stenosis (231)	11	6	54.5%
2416	Loss of concentration (1589)	11	1	9.1%
2417	Cushings disease - adrenal dependent (382)	11	3	27.3%
2418	Sore lip (2105)	11	0	0.0%
2419	Dental discolouration (283)	11	2	18.2%
2420	Epileptic fit (1443)	11	2	18.2%
2421	Menstruation irregular (1608)	11	0	0.0%
2422	Ventricular fibrillation (2427)	11	11	100.0%
2423	Gangrene (2085)	11	9	81.8%
2424	Bile duct inflammation (1344)	11	5	45.5%
2425	Frequent micturition (734)	11	1	9.1%
2426	Myelitis (1123)	11	5	45.5%
2427	Gut pain (1503)	11	3	27.3%
2428	Liver damage aggravated (1579)	11	8	72.7%
2429	Food intolerance syndrome (547)	11	2	18.2%
2430	Joint ache (587)	11	1	9.1%
2431	Hallucinations (1509)	11	0	0.0%
2432	Cognitive and attention disorders NOS (1381)	11	1	9.1%
2433	NT - intestinal tumour (adenocarcinoma/adenoma/gastro intestinal stromal tumour (gist)) (2354)	11	7	63.6%
2434	Glucose intolerance (392)	11	2	18.2%
2435	Panosteitis (1948)	11	3	27.3%
2436	ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (93049)	11	3	27.3%
2437	Vagal shock (2381)	11	2	18.2%
2438	Low parathyroid (PTH) concentration (2665)	11	1	9.1%
2439	Aqueous flare (2760)	11	1	9.1%
2440	Lack of efficacy (virus) - herpesvirus NOS (2820)	11	7	63.6%
2441	Eosinophilic enteritis (2334)	11	4	36.4%
2442	Decreased red cell distribution width (RDW) (2858)	11	2	18.2%
2443	Difficulty getting in car (2870)	11	1	9.1%
2444	Residues in eggs (2040)	10	1	10.0%
2445	PR-MULTIPLE SITES, EDEMA (99649)	10	10	100.0%
2446	PR-PROSTATE, LESION(S) (99669)	10	8	80.0%
2447	Orchitis (806)	10	2	20.0%
2448	Anoxia (829)	10	5	50.0%
2449	PR-JOINT(S), LESION(S) (99624)	10	8	80.0%
2450	Ischaemia NOS (230)	10	5	50.0%
2451	Feelings of weakness (1472)	10	0	0.0%
2452	Blackout (1345)	10	0	0.0%
2453	Hyposalivation (1076)	10	2	20.0%
2454	Papillary necrosis (1253)	10	10	100.0%
2455	Throat tingling (1272)	10	0	0.0%
2456	Congenital renal and urinary tract disorder NOS (710)	10	7	70.0%
2457	NT - (luminal) enteropathy (2332)	10	3	30.0%
2458	BLOOD CHEMISTRY ABNORMAL (99223)	10	1	10.0%
2459	Renal vascular disorder (723)	10	5	50.0%
2460	Throat tightness (1838)	10	0	0.0%
2461	Throat constriction (1835)	10	0	0.0%
2462	Genital tract pruritus (1497)	10	2	20.0%
2463	NT - hepatic or biliary tumour (hepatocarcinoma/cholangiocarcinoma/ adenoma/cholangioma) (2329)	10	7	70.0%
2464	Stiff knee (1792)	10	1	10.0%
2465	Uric acid crystals (2256)	10	1	10.0%
2466	Delayed fracture union (583)	10	0	0.0%
2467	Suckling disorder NOS (2437)	10	8	80.0%
2468	Bronchial secretion (1169)	10	2	20.0%
2469	Ectropion (424)	10	1	10.0%
2470	Selenium toxicity signs (2020)	10	9	90.0%
2471	Optic disc oedema (2237)	10	2	20.0%
2472	Dysphonia (1268)	10	1	10.0%
2473	Peritoneal fluid, high white blood cell count (2714)	10	5	50.0%
2474	Haemorrhagic enteritis (2337)	10	7	70.0%
2475	Drug device use error (93091)	10	1	10.0%
2476	Plasmacytoma (2954)	10	1	10.0%
2477	Lack of efficacy (mycoplasma) - Haemobartonella (2807)	10	1	10.0%
2478	Urinary tract neoplasm NOS (742)	10	3	30.0%
2479	Device use issues NOS (3038)	10	0	0.0%
2480	Lymphangiectasia (2348)	10	1	10.0%
2481	Injection site cyst (3057)	10	0	0.0%

Compiled by PlainBreed