Reaction profile

The FDA adverse-event record for decreased percentage of reticulocytes

423 FDA reports name decreased percentage of reticulocytes, a high-volume reaction in the CVM extract (VeDDRA 2212). Plate stamps and neighbourhood peers follow.

#705 of 2,481
by report volume (all reactions)
423
reports citing this reaction
21.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased percentage of reticulocytes has 423 reports now versus 393 in that prior snapshot: 30 more (7.6%).

Report change
+30
Death-coded reports
+7
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased percentage of reticulocytes changes

FDA AER · VeDDRA plate

Code 2212 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 423 reports
  • DEATH-HOT 21.3%
  • MID-PACK #705/2481
  • PHOTO-FINISH Anuria
  • SPECIES-DOG Dog · 362
  • DRUG-LEAD Maropitant Citrate · 61
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anuria (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Decreased percentage of reticulocytes

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Lip oedema (see also… · near425Decreased heart rate · near424Anuria · near423Decreased percentage… · this…423Respiratory tract inf… · near422Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased percentage of reticulocytes

What the FDA AER plate says about Decreased percentage of reticulocytes

Signature read: 90 death-coded reports is a heavy tail count for Decreased percentage of reticulocytes in the CVM extract. Report volume is upper-third scale: 423 named reports in the openFDA extract. 90 of 423 reports were death-coded (21.3% of named reports, not a population mortality rate). Nearest volume peer: Anuria (±0 reports). Lead species Dog (362). Lead co-reported drug Maropitant Citrate (61).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 362
Cat 61

Breeds Most Affected

Retriever - Labrador 59
Domestic Shorthair 38
Retriever - Golden 29
Crossbred Canine/dog 27
Shepherd Dog - German 14
Boxer (German Boxer) 13
Shih Tzu 10
Siberian Husky 10
Shepherd Dog - Australian 9
Dachshund (unspecified) 8

Associated Drugs

Maropitant Citrate 61
Oclacitinib Maleate 60
Afoxolaner 46
Ilunocitinib 45
Carprofen 42
Gabapentin 40
Lotilaner 32
Prednisone 28
Doxycycline 28
Metronidazole 23
Ivermectin + Pyrantel As Pamoate Salt 22
Milbemycin Oxime + Praziquantel 22
Bedinvetmab 22
Fluid Therapy 20
Enrofloxacin 19
Meloxicam 18
Cyclosporine 18
Milbemycin Oxime + Spinosad 17
Buprenorphine 17
Moxidectin 15

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased percentage of reticulocytes, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (423 here).

Similar death-coded share

Nearest other reactions by death-coded share (21.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased percentage of reticulocytes (#705 of 2,481 by report volume); death-coded 21.3%. PlainBreed reaction plate · death-coded report count stamp 90 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →