Reaction profile

The FDA adverse-event record for prolapse of the nictitating membrane

184 FDA adverse-event reports reference prolapse of the nictitating membrane (VeDDRA 1103). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1081 of 2,481
by report volume (all reactions)
184
reports citing this reaction
12.5%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prolapse of the nictitating membrane has 184 reports now versus 181 in that prior snapshot: 3 more (1.7%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prolapse of the nictitating membrane changes

FDA AER · VeDDRA plate

Code 1103 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 184 reports
  • DEATH-ELEV 12.5%
  • MID-PACK #1081/2481
  • PHOTO-FINISH BANDS(NEUTROPHILS) HI…
  • SPECIES-CAT Cat · 94
  • DRUG-LEAD Spinosad · 21
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: BANDS(NEUTROPHILS) HIGH, BLOOD (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Prolapse of the nictitating membrane

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Coughing up blood · near185Epidermal collarette · near185Peripheral nervous sy… · near185BANDS(NEUTROPHILS) HI… · near184Prolapse of the nicti… · thi…184Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Prolapse of the nictitating membrane

What the FDA AER plate says about Prolapse of the nictitating membrane

Signature read: report volume at 184 (#1081 of 2,481) is the standout scale stamp on Prolapse of the nictitating membrane. Report volume sits in the middle third of the reaction corpus. 23 of 184 reports were death-coded (12.5% of named reports, not a population mortality rate). Nearest volume peer: BANDS(NEUTROPHILS) HIGH, BLOOD (±0 reports). Lead species Cat (94). Lead co-reported drug Spinosad (21).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 94
Dog 89
Cattle 1

Breeds Most Affected

Domestic (unspecified) 40
Domestic Shorthair 28
Retriever - Labrador 12
Boxer (German Boxer) 11
Retriever - Golden 9
Crossbred Canine/dog 9
Cat (unknown) 5
Domestic Longhair 5
Maine Coon 4
Spaniel - Cocker American 3

Associated Drugs

Spinosad 21
Selamectin 13
Milbemycin Oxime + Spinosad 13
Cefovecin Sodium 10
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 8
Meloxicam 7
Carprofen 7
Cefovecin 7
Pyrantel Pamoate;Sarolaner 7
Oclacitinib Maleate 7
Isoflurane 6
Dexmedetomidine Hydrochloride 5
Ketamine Hydrochloride 5
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 5
Bedinvetmab 5
Imidacloprid, Moxidectin 4
Maropitant 4
Methylprednisolone Acetate 4
Nitenpyram 4
Emodepside + Praziquantel 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Prolapse of the nictitating membrane, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (12.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prolapse of the nictitating membrane (#1081 of 2,481 by report volume); death-coded 12.5%. PlainBreed reaction plate · report volume stamp 184 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →