Reaction profile

The FDA adverse-event record for laryngeal paralysis

134 FDA adverse-event reports reference laryngeal paralysis (VeDDRA 1991). See the species, breeds, and drugs most associated with it below.

134
reports citing this reaction
35.8%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
134
Total Reports
48
Deaths
35.8%
Death Rate

Species Most Affected

Dog 130
Horse 3
Cattle 1

Breeds Most Affected

Retriever - Labrador 47
Retriever - Golden 17
Dog (unknown) 6
Crossbred Canine/dog 4
Shepherd Dog - Australian 4
Collie - Border 3
Poodle - Standard 2
Spaniel - Cocker American 2
Spaniel - Springer English 2
Spaniel (unspecified) 2

Associated Drugs

Bedinvetmab 52
Gabapentin 12
Trilostane 11
Milbemycin Oxime + Spinosad 10
Carprofen 10
Afoxolaner 8
Grapiprant 7
Anti-Il31 Mab Mcs Lot #1283563 6
Galliprant 6
Milbemycin Oxime + Praziquantel 5
Prednisone 4
Moxidectin 4
Oclacitinib Maleate 4
Maropitant Citrate 4
Fluralaner 13.64% 12-Week Chew 4
Deracoxib 3
Spinosad 3
Rabies Virus, Kv 3
Fish Oil 3
Cyclosporine 3

Laryngeal paralysis Reaction Insights

134 reports name Laryngeal paralysis; 48 recorded a death outcome (35.8% of reported events, not a population-level mortality rate). VeDDRA code: 1991.

By species: Dog (130 reports), Horse (3 reports), Cattle (1 reports). By breed: Retriever - Labrador (47), Retriever - Golden (17), Dog (unknown) (6).

Most co-reported drugs: Bedinvetmab (52 reports), Gabapentin (12 reports), Trilostane (11 reports), Milbemycin Oxime + Spinosad (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.