Reaction profile

The FDA adverse-event record for hind limb ataxia

1,886 FDA adverse-event reports reference hind limb ataxia (VeDDRA 1134). See the species, breeds, and drugs most associated with it below.

1,886
reports citing this reaction
13.1%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
1,886
Total Reports
247
Deaths
13.1%
Death Rate

Species Most Affected

Dog 1,528
Cat 303
Horse 39
Cattle 8
Pig 3
Ferret 1
Other Canids 1
Cockatiel 1
Other Birds 1
Turkey 1

Breeds Most Affected

Retriever - Labrador 216
Domestic Shorthair 200
Shepherd Dog - German 80
Crossbred Canine/dog 80
Retriever - Golden 69
Chihuahua 51
Shih Tzu 49
Boxer (German Boxer) 44
Shepherd Dog - Australian 39
Dachshund (unspecified) 38

Associated Drugs

Bedinvetmab 340
Milbemycin Oxime + Spinosad 252
Afoxolaner 154
Gabapentin 126
Carprofen 124
Spinosad 85
Maropitant Citrate 74
Imidacloprid + Moxidectin 58
Oclacitinib Maleate 58
Sarolaner 58
Fluralaner 13.64% 12-Week Chew 52
Ivermectin + Pyrantel As Pamoate Salt 51
Frunevetmab 51
Pyrantel Pamoate;Sarolaner 50
Trilostane 49
Prednisone 46
Moxidectin 46
Enrofloxacin 42
Grapiprant 42
Cefovecin 41

Hind limb ataxia Reaction Insights

1,886 reports name Hind limb ataxia; 247 recorded a death outcome (13.1% of reported events, not a population-level mortality rate). VeDDRA code: 1134.

By species: Dog (1,528 reports), Cat (303 reports), Horse (39 reports). By breed: Retriever - Labrador (216), Domestic Shorthair (200), Shepherd Dog - German (80).

Most co-reported drugs: Bedinvetmab (340 reports), Milbemycin Oxime + Spinosad (252 reports), Afoxolaner (154 reports), Gabapentin (126 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.