Hind limb ataxia

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VeDDRA Code: 1134

1,886 adverse event reports referencing this reaction

1,886
Total Reports
247
Deaths
1310.0%
Death Rate

Species Most Affected

Dog 1,528
Cat 303
Horse 39
Cattle 8
Pig 3
Ferret 1
Other Canids 1
Cockatiel 1
Other Birds 1
Turkey 1

Breeds Most Affected

Retriever - Labrador 216
Domestic Shorthair 200
Shepherd Dog - German 80
Crossbred Canine/dog 80
Retriever - Golden 69
Chihuahua 51
Shih Tzu 49
Boxer (German Boxer) 44
Shepherd Dog - Australian 39
Dachshund (unspecified) 38

Associated Drugs

Bedinvetmab 340
Milbemycin Oxime + Spinosad 252
Afoxolaner 154
Gabapentin 126
Carprofen 124
Spinosad 85
Maropitant Citrate 74
Imidacloprid + Moxidectin 58
Oclacitinib Maleate 58
Sarolaner 58
Fluralaner 13.64% 12-Week Chew 52
Ivermectin + Pyrantel As Pamoate Salt 51
Frunevetmab 51
Pyrantel Pamoate;Sarolaner 50
Trilostane 49
Prednisone 46
Moxidectin 46
Enrofloxacin 42
Grapiprant 42
Cefovecin 41

Data Summary

Metric Value
Total reports referencing reaction 1,886
Reports with fatal outcome 247
Case-fatality rate (reported events) 1310.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1134.

Hind limb ataxia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,886 adverse event reports that reference Hind limb ataxia as a reaction term, including 247 reports with a death outcome — a 1310.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1134, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hind limb ataxia appears most frequently in reports for Dog (1,528 reports), Cat (303 reports), Horse (39 reports) — with Dog dominating at 1,528 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (216), Domestic Shorthair (200), Shepherd Dog - German (80). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hind limb ataxia are Bedinvetmab (340 reports), Milbemycin Oxime + Spinosad (252 reports), Afoxolaner (154 reports), Gabapentin (126 reports), with Bedinvetmab appearing alongside this reaction in 340 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial