Reaction profile

The FDA adverse-event record for throat pain

31 FDA adverse-event reports reference throat pain (VeDDRA 1837). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
3.2%
death-coded share
Human
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
31
Total Reports
1
Deaths
3.2%
Death Rate

Species Most Affected

Human 22
Dog 8
Cat 1

Breeds Most Affected

Unknown 22
Boxer (German Boxer) 2
Dachshund - Miniature 1
Maltese 1
Bichon Frise 1
Dachshund (unspecified) 1
Spaniel - King Charles Cavalier 1
Domestic Shorthair 1
Chihuahua 1

Associated Drugs

Milbemycin Oxime + Spinosad 10
Imidacloprid + Moxidectin 3
Selamectin 3
Nitenpyram 2
Fluralaner Spot-On Solution 2
Ciprofloxacin 2
Spinosad 1
Hormone Replacement Therapy 1
Trilostane 1
Oclacitinib Maleate 1
Afoxolaner 1
Ivermectin + Pyrantel As Pamoate Salt 1
Afoxolaner 28.3 Mg Chewable Tablets 1
Lithium 1
Buspirone Hcl 1
Fluoxetine Hcl 1
Tilmicosin 1
Eprinomectin 1
Distemper Vaccine 1
Mycophenolate Mofetil 1

Throat pain Reaction Insights

31 reports name Throat pain; 1 recorded a death outcome (3.2% of reported events, not a population-level mortality rate). VeDDRA code: 1837.

By species: Human (22 reports), Dog (8 reports), Cat (1 reports). By breed: Unknown (22), Boxer (German Boxer) (2), Dachshund - Miniature (1).

Most co-reported drugs: Milbemycin Oxime + Spinosad (10 reports), Imidacloprid + Moxidectin (3 reports), Selamectin (3 reports), Nitenpyram (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.