Reaction profile

The FDA adverse-event record for congestive heart failure

435 FDA reports name congestive heart failure, a high-volume reaction in the CVM extract (VeDDRA 2429). Plate stamps and neighbourhood peers follow.

#691 of 2,481
by report volume (all reactions)
435
reports citing this reaction
52.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Congestive heart failure has 435 reports now versus 423 in that prior snapshot: 12 more (2.8%).

Report change
+12
Death-coded reports
+7
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Congestive heart failure changes

FDA AER · VeDDRA plate

Code 2429 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 435 reports
  • DEATH-HOT 52.2%
  • MID-PACK #691/2481
  • PHOTO-FINISH Tongue protrusion
  • SPECIES-DOG Dog · 339
  • DRUG-LEAD Pimobendan · 57
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tongue protrusion (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Congestive heart failure

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Congestive heart fail… · thi…435Tongue protrusion · near434Dermal cyst(s) · near433Erythematous rash · near432Food refusal · near431Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Congestive heart failure

Congestive heart failure: high death-coded share in the FDA AER plate

Signature read: 227 death-coded reports is a heavy tail count for Congestive heart failure in the CVM extract. Report volume is upper-third scale: 435 named reports in the openFDA extract. Death-coded share is upper-third: 227 of 435 reports (52.2% of named reports). Nearest volume peer: Tongue protrusion (±1 reports). Lead species Dog (339). Lead co-reported drug Pimobendan (57).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 339
Cat 88
Cattle 5
Rabbit 1
Other Birds 1
Horse 1

Breeds Most Affected

Domestic Shorthair 50
Chihuahua 34
Crossbred Canine/dog 27
Shih Tzu 25
Dog (unknown) 21
Spaniel - King Charles Cavalier 19
Maltese 14
Dachshund (unspecified) 14
Spitz - German Pomeranian 14
Terrier - Yorkshire 13

Associated Drugs

Pimobendan 57
Milbemycin Oxime + Spinosad 48
Furosemide 36
Trilostane 30
Bedinvetmab 30
Ivermectin + Pyrantel As Pamoate Salt 29
Moxidectin 21
Fluralaner 13.64% 12-Week Chew 20
Cefovecin 18
Maropitant Citrate 17
Frunevetmab 17
Afoxolaner 16
Gabapentin 16
Spinosad 15
Oclacitinib Maleate 15
Prednisone 14
Milbemycin Oxime + Praziquantel 14
Carprofen 13
Fluralaner Chew Tablets 13
Enalapril 13

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Congestive heart failure, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (435 here).

Similar death-coded share

Nearest other reactions by death-coded share (52.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Congestive heart failure (#691 of 2,481 by report volume); death-coded 52.2%. PlainBreed reaction plate · death-coded report count stamp 227 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →