Reaction profile

The FDA adverse-event record for pyoderma

1,328 FDA adverse-event reports reference pyoderma (VeDDRA 961). See the species, breeds, and drugs most associated with it below.

1,328
reports citing this reaction
6.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
1,328
Total Reports
80
Deaths
6.0%
Death Rate

Species Most Affected

Dog 1,236
Cat 90
Horse 1
Human 1

Breeds Most Affected

Retriever - Labrador 137
Crossbred Canine/dog 90
Shepherd Dog - German 74
Retriever - Golden 70
Pit Bull 48
Domestic Shorthair 44
Shih Tzu 42
Bulldog 32
Terrier - Yorkshire 30
Boxer (German Boxer) 30

Associated Drugs

Milbemycin Oxime + Spinosad 204
Oclacitinib Maleate 203
Trilostane 97
Spinosad 95
Fluralaner Chew Tablets 84
Afoxolaner 78
Carprofen 70
Cyclosporine 65
Prednisone 56
Bedinvetmab 50
Selamectin 49
Anti-Il31 Mab Mcs Lot #1283563 48
Milbemycin Oxime + Praziquantel 41
Imidacloprid + Moxidectin 38
Cefpodoxime Proxetil 37
Cephalexin 35
Moxidectin 28
Gabapentin 28
Cyclosporine A 27
Cefovecin 26

Pyoderma Reaction Insights

1,328 reports name Pyoderma; 80 recorded a death outcome (6.0% of reported events, not a population-level mortality rate). VeDDRA code: 961.

By species: Dog (1,236 reports), Cat (90 reports), Horse (1 reports). By breed: Retriever - Labrador (137), Crossbred Canine/dog (90), Shepherd Dog - German (74).

Most co-reported drugs: Milbemycin Oxime + Spinosad (204 reports), Oclacitinib Maleate (203 reports), Trilostane (97 reports), Spinosad (95 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.