Reaction profile

The FDA adverse-event record for skin ulcer

743 FDA adverse-event reports reference skin ulcer (VeDDRA 1194). See the species, breeds, and drugs most associated with it below.

743
reports citing this reaction
9.8%
death-coded share
Dog
most-affected species
Frunevetmab
most-associated drug
Verify with FDA CVM →
743
Total Reports
73
Deaths
9.8%
Death Rate

Species Most Affected

Dog 469
Cat 253
Horse 5
Human 5
Rabbit 4
Cattle 3
Pig 1
Guinea Pig 1
Other Canids 1
Donkey 1

Breeds Most Affected

Domestic Shorthair 135
Retriever - Labrador 73
Domestic (unspecified) 44
Crossbred Canine/dog 36
Shepherd Dog - German 28
Domestic Longhair 21
Chihuahua 20
Retriever - Golden 18
Terrier - Bull - American Pit 15
Pit Bull 13

Associated Drugs

Frunevetmab 111
Carprofen 74
Cefovecin 66
Oclacitinib Maleate 65
Selamectin 54
Gabapentin 47
Prednisone 46
Meloxicam 33
Milbemycin Oxime + Spinosad 31
Bedinvetmab 30
Maropitant Citrate 25
Trilostane 23
Afoxolaner 23
Anti-Il31 Mab Mcs Lot #1283563 22
Enrofloxacin 20
Cefovecin Sodium 19
Moxidectin 19
Cefpodoxime Proxetil 19
Spinosad 18
Prednisolone 18

Skin ulcer Reaction Insights

743 reports name Skin ulcer; 73 recorded a death outcome (9.8% of reported events, not a population-level mortality rate). VeDDRA code: 1194.

By species: Dog (469 reports), Cat (253 reports), Horse (5 reports). By breed: Domestic Shorthair (135), Retriever - Labrador (73), Domestic (unspecified) (44).

Most co-reported drugs: Frunevetmab (111 reports), Carprofen (74 reports), Cefovecin (66 reports), Oclacitinib Maleate (65 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.