Reaction profile

The FDA adverse-event record for joint oedema

Name: Joint oedema - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

36 FDA reports name joint oedema, a lower-volume reaction in the CVM extract (VeDDRA 572). Plate stamps and neighbourhood peers follow.

#1910 of 2,481
by report volume (all reactions): 36
reports citing this reaction: 22.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Joint oedema has 36 reports now versus 36 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Joint oedema changes

FDA AER · VeDDRA plate

Code 572 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 36 reports
DEATH-HOT 22.2%
LOWER-Q #1910/2481
PHOTO-FINISH Abnormal birth weight
SPECIES-DOG Dog · 26
DRUG-LEAD Carprofen · 6
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal birth weight (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Joint oedema

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Joint oedema

What the FDA AER plate says about Joint oedema

Signature read: 36 reports place Joint oedema in the lower third of FDA AER volume (#1910 of 2,481). Report volume is lower-third scale: 36 named reports in the openFDA extract. 8 of 36 reports were death-coded (22.2% of named reports, not a population mortality rate). Nearest volume peer: Abnormal birth weight (±0 reports). Lead species Dog (26). Lead co-reported drug Carprofen (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 26

Horse 5

Cat 4

Human 1

Breeds Most Affected

Retriever - Labrador 5

Domestic Shorthair 2

Weimaraner 2

Shepherd Dog - German 2

Boxer (German Boxer) 2

Retriever - Golden 2

Paint 1

Quarter Horse 1

Deutsche Dogge, Great Dane 1

Rottweiler 1

Associated Drugs

Carprofen 6

Enrofloxacin 5

Bedinvetmab 5

Gabapentin 3

Fluralaner Chew Tablets 3

Hyaluronate Sodium 2

Milbemycin Oxime + Spinosad 2

Butorphanol 2

Maropitant Citrate 2

Milk Thistle 2

Chinese Herbal 2

Tramadol 2

Deracoxib 2

Moxidectin 2

Canine Da2Ppv (Orig S-P Us) Lv 2

Afoxolaner 2

Oclacitinib Maleate 2

Imidacloprid + Moxidectin 1

Unknown Vaccines 1

Spinosad 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Joint oedema (#1910 of 2,481 by report volume); death-coded 22.2%. PlainBreed reaction plate · report volume stamp 36 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →