Bradypnoea

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VeDDRA Code: 833

211 adverse event reports referencing this reaction

211
Total Reports
65
Deaths
3080.0%
Death Rate

Species Most Affected

Dog 158
Cat 31
Horse 8
Monkey 3
Mouse 2
Snake 2
Human 1
Cattle 1
Turtle 1
Alpaca 1

Breeds Most Affected

Retriever - Labrador 11
Dog (unknown) 11
Domestic Shorthair 11
Domestic (unspecified) 10
Shih Tzu 9
Chihuahua 8
Mixed (Dog) 7
Crossbred Canine/dog 6
Terrier - Jack Russell 5
Unknown 5

Associated Drugs

Dexmedetomidine Hydrochloride 35
Isoflurane 27
Ketamine Hydrochloride 14
Milbemycin Oxime + Spinosad 12
Propofol 11
Ketamine 10
Spinosad 9
Moxidectin 9
Ivermectin 8
Sevoflurane 7
Imidacloprid + Moxidectin 6
Vaccine 6
Dewormer 6
Butorphanol 6
Dexmedetomidine 6
Cefovecin Sodium 5
Alfaxalone 5
Butorphanol Tartrate 4
Acepromazine Maleate 4
Carprofen 4

Data Summary

Metric Value
Total reports referencing reaction 211
Reports with fatal outcome 65
Case-fatality rate (reported events) 3080.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 833.

Bradypnoea Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 211 adverse event reports that reference Bradypnoea as a reaction term, including 65 reports with a death outcome — a 3080.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 833, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Bradypnoea appears most frequently in reports for Dog (158 reports), Cat (31 reports), Horse (8 reports) — with Dog dominating at 158 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (11), Dog (unknown) (11), Domestic Shorthair (11). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Bradypnoea are Dexmedetomidine Hydrochloride (35 reports), Isoflurane (27 reports), Ketamine Hydrochloride (14 reports), Milbemycin Oxime + Spinosad (12 reports), with Dexmedetomidine Hydrochloride appearing alongside this reaction in 35 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial