Reaction profile

The FDA adverse-event record for anisocoria

697 FDA adverse-event reports reference anisocoria (VeDDRA 670). See the species, breeds, and drugs most associated with it below.

697
reports citing this reaction
17.9%
death-coded share
Cat
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
697
Total Reports
125
Deaths
17.9%
Death Rate

Species Most Affected

Cat 382
Dog 313
Human 2

Breeds Most Affected

Domestic Shorthair 231
Retriever - Labrador 41
Domestic Longhair 36
Chihuahua 31
Domestic (unspecified) 28
Shepherd Dog - Australian 23
Domestic Mediumhair 20
Siberian Husky 16
Terrier - Yorkshire 15
Cat (unknown) 13

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 93
Maropitant Citrate 76
Cefovecin 47
Buprenorphine 46
Moxidectin 41
Gabapentin 34
Bedinvetmab 30
Cefovecin Sodium 28
Milbemycin Oxime + Spinosad 27
Afoxolaner 26
Selamectin 24
Prednisone 21
Fluralaner Chew Tablets 21
Oclacitinib Maleate 20
Spinosad 19
Betamethasone + Florfenicol + Terbinafine 19
Florfenicol, Terbinafine, Betamethasone Acetate 18
Isoflurane 17
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 16
Robenacoxib 15

Anisocoria Reaction Insights

697 reports name Anisocoria; 125 recorded a death outcome (17.9% of reported events, not a population-level mortality rate). VeDDRA code: 670.

By species: Cat (382 reports), Dog (313 reports), Human (2 reports). By breed: Domestic Shorthair (231), Retriever - Labrador (41), Domestic Longhair (36).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (93 reports), Maropitant Citrate (76 reports), Cefovecin (47 reports), Buprenorphine (46 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.