Reaction profile

The FDA adverse-event record for spasticity

31 FDA reports name spasticity, a lower-volume reaction in the CVM extract (VeDDRA 701). Plate stamps and neighbourhood peers follow.

#1984 of 2,481
by report volume (all reactions)
31
reports citing this reaction
19.4%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Spasticity has 31 reports now versus 31 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Spasticity changes

FDA AER · VeDDRA plate

Code 701 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 31 reports
  • DEATH-ELEV 19.4%
  • LOWER-Q #1984/2481
  • PHOTO-FINISH ABNORMAL TEST RESULT,…
  • SPECIES-DOG Dog · 18
  • DRUG-LEAD Buprenorphine · 6
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Spasticity

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL TEST RESULT,… · near31ALBUMIN HIGH, URINE · near31BILE ACIDS ABNORMAL,… · near31Clonic seizure · near31Spasticity · this reaction31Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Spasticity

What the FDA AER plate says about Spasticity

Signature read: 31 reports place Spasticity in the lower third of FDA AER volume (#1984 of 2,481). Report volume is lower-third scale: 31 named reports in the openFDA extract. 6 of 31 reports were death-coded (19.4% of named reports, not a population mortality rate). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Dog (18). Lead co-reported drug Buprenorphine (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Buprenorphine appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 18
Cat 12
Cattle 1

Breeds Most Affected

Domestic Shorthair 7
Shepherd Dog - Australian 3
Pointing Dog - Hungarian Short-haired (Vizsla) 3
Retriever - Golden 2
Greyhound - Italian 1
Dog (unknown) 1
Domestic Mediumhair 1
Cat (unknown) 1
Cattle (unknown) 1
Terrier - Yorkshire 1

Associated Drugs

Buprenorphine 6
Propofol 4
Isoflurane 3
Milbemycin Oxime + Spinosad 3
Pyrantel Pamoate;Sarolaner 3
Cefovecin Sodium 3
Maropitant Citrate 3
Spinosad 2
Sarolaner 2
Trazodone 2
Hydromorphone 2
Chlorpheniramine Maleate 1
Ivermectin Chewable 165Mcg 1
Dexmedetomidine Hydrochloride 1
Butorphanol 1
Cefovecin 1
Amoxicillin As Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 1
Fluconazole 1
Doramectin; Phenol 1
Tiletamine Hcl; Zolazapam Hcl 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Spasticity (#1984 of 2,481 by report volume); death-coded 19.4%. PlainBreed reaction plate · report volume stamp 31 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →