Reaction profile

The FDA adverse-event record for decreased mean corpuscular haemoglobin concentration (mchc)

105 FDA adverse-event reports reference decreased mean corpuscular haemoglobin concentration (mchc) (VeDDRA 3090). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1366 of 2,481
by report volume (all reactions)
105
reports citing this reaction
23.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased mean corpuscular haemoglobin concentration (MCHC) has 105 reports now versus 90 in that prior snapshot: 15 more (16.7%).

Report change
+15
Death-coded reports
+4
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased mean corpuscular haemoglobin concentration (MCHC) changes

FDA AER · VeDDRA plate

Code 3090 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 105 reports
  • DEATH-HOT 23.8%
  • MID-PACK #1366/2481
  • PHOTO-FINISH Hyperaemia
  • SPECIES-DOG Dog · 80
  • DRUG-LEAD Maropitant Citrate · 18
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hyperaemia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Decreased mean corpuscular haemoglobin concent…

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Decreased mean corpus… · thi…105Hyperaemia · near105Injection site stiffn… · near105Lack of efficacy (neo… · near105Pyometra · near105Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased mean corpuscular haemoglobin concentration (MCHC)

What the FDA AER plate says about Decreased mean corpuscular haemoglobin concentration (MCHC)

Signature read: Decreased mean corpuscular haemoglobin concentration (MCHC)'s 23.8% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. 25 of 105 reports were death-coded (23.8% of named reports, not a population mortality rate). Nearest volume peer: Hyperaemia (±0 reports). Lead species Dog (80). Lead co-reported drug Maropitant Citrate (18).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 80
Cat 20
Horse 5

Breeds Most Affected

Domestic Shorthair 14
Retriever - Labrador 8
Shepherd Dog - Australian 5
Dog (other) 5
Crossbred Canine/dog 4
Shih Tzu 4
Pit Bull 4
Retriever - Golden 3
Shepherd Dog - German 3
Terrier - Yorkshire 3

Associated Drugs

Maropitant Citrate 18
Ilunocitinib 16
Afoxolaner 9
Prednisone 9
Oclacitinib Maleate 9
Fluid Therapy 9
Gabapentin 8
Eprinomectin + Esafoxolaner + Praziquantel 7
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 7
Rabies Vaccine 7
Doxycycline 6
Fluralaner 13.64% 12-Week Chew 6
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 6
Dexamethasone 5
Clopidogrel 5
Metronidazole 5
Mirtazapine 5
Capromorelin 5
Dexmedetomidine 5
Cephalexin 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased mean corpuscular haemoglobin concentration (MCHC), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (23.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased mean corpuscular haemoglobin concentration (MCHC) (#1366 of 2,481 by report volume); death-coded 23.8%. PlainBreed reaction plate · death-coded share stamp 23.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →