Reaction profile

The FDA adverse-event record for pr-small intestine, lesion(s)

169 FDA adverse-event reports reference pr-small intestine, lesion(s) (VeDDRA 99676). See the species, breeds, and drugs most associated with it below.

169
reports citing this reaction
84.6%
death-coded share
Dog
most-affected species
Deracoxib
most-associated drug
Verify with FDA CVM →
169
Total Reports
143
Deaths
84.6%
Death Rate

Species Most Affected

Dog 126
Cat 28
Cattle 9
Horse 3
Pig 2
Turkey 1

Breeds Most Affected

Retriever - Labrador 21
Crossbred Canine/dog 17
Domestic (unspecified) 11
Retriever - Golden 8
Boxer (German Boxer) 6
Chihuahua 5
Persian 5
Holstein-Friesian also known as Holstein 5
Mastiff 4
Shepherd Dog - German 4

Associated Drugs

Deracoxib 25
Carprofen 25
Meloxicam 12
Maropitant 10
Maropitant Citrate 10
Cefovecin Sodium 9
Firocoxib 6
Afoxolaner 6
Moxidectin 5
Dexmedetomidine Hydrochloride 5
Robenacoxib 5
Fluralaner Chew Tablets 5
Spinosad 3
Selamectin 3
Tildipirosin 3
Dexamethasone 3
Tramadol 3
Ivermectin + Pyrantel As Pamoate Salt 3
Grapiprant 3
Sulfadimethoxine 2

PR-SMALL INTESTINE, LESION(S) Reaction Insights

169 reports name PR-SMALL INTESTINE, LESION(S); 143 recorded a death outcome (84.6% of reported events, not a population-level mortality rate). VeDDRA code: 99676.

By species: Dog (126 reports), Cat (28 reports), Cattle (9 reports). By breed: Retriever - Labrador (21), Crossbred Canine/dog (17), Domestic (unspecified) (11).

Most co-reported drugs: Deracoxib (25 reports), Carprofen (25 reports), Meloxicam (12 reports), Maropitant (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.