Reaction profile

The FDA adverse-event record for proprioception abnormality

461 FDA adverse-event reports reference proprioception abnormality (VeDDRA 1155). See the species, breeds, and drugs most associated with it below.

461
reports citing this reaction
20.6%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
461
Total Reports
95
Deaths
20.6%
Death Rate

Species Most Affected

Dog 421
Cat 34
Horse 5
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 52
Retriever - Labrador 42
Retriever - Golden 24
Boxer (German Boxer) 19
Shepherd Dog - German 16
Chihuahua 13
Domestic Shorthair 13
Pit Bull 12
Domestic (unspecified) 12
Terrier - Yorkshire 11

Associated Drugs

Bedinvetmab 78
Carprofen 72
Gabapentin 28
Spinosad 27
Afoxolaner 26
Grapiprant 24
Milbemycin Oxime + Spinosad 23
Melarsomine Dihydrochloride 20
Maropitant Citrate 17
Moxidectin 15
Deracoxib 14
Firocoxib 12
Meloxicam 12
Melarsomine Dihydrochloride Injection 11
Tramadol 10
Polysulfated Glycosaminoglycan 10
Ivermectin 9
Trazodone 9
Selamectin 8
Ivermectin + Pyrantel As Pamoate Salt 8

Proprioception abnormality Reaction Insights

461 reports name Proprioception abnormality; 95 recorded a death outcome (20.6% of reported events, not a population-level mortality rate). VeDDRA code: 1155.

By species: Dog (421 reports), Cat (34 reports), Horse (5 reports). By breed: Crossbred Canine/dog (52), Retriever - Labrador (42), Retriever - Golden (24).

Most co-reported drugs: Bedinvetmab (78 reports), Carprofen (72 reports), Gabapentin (28 reports), Spinosad (27 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.