Reaction profile

The FDA adverse-event record for proprioception abnormality

480 FDA reports name proprioception abnormality, a high-volume reaction in the CVM extract (VeDDRA 1155). Plate stamps and neighbourhood peers follow.

#657 of 2,481
by report volume (all reactions)
480
reports citing this reaction
20.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Proprioception abnormality has 480 reports now versus 475 in that prior snapshot: 5 more (1.1%).

Report change
+5
Death-coded reports
+2
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Proprioception abnormality changes

FDA AER · VeDDRA plate

Code 1155 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 480 reports
  • DEATH-HOT 20.8%
  • MID-PACK #657/2481
  • PHOTO-FINISH Hypocalcaemia
  • SPECIES-DOG Dog · 437
  • DRUG-LEAD Bedinvetmab · 90
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hypocalcaemia (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Proprioception abnormality

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hypocalcaemia · near481Respiratory signs · near481Proprioception abnorm… · thi…480Abdominal effusion · near478Oral cavity disorder… · near478Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Proprioception abnormality

What the FDA AER plate says about Proprioception abnormality

Signature read: 100 death-coded reports is a heavy tail count for Proprioception abnormality in the CVM extract. Report volume is upper-third scale: 480 named reports in the openFDA extract. 100 of 480 reports were death-coded (20.8% of named reports, not a population mortality rate). Nearest volume peer: Hypocalcaemia (±1 reports). Lead species Dog (437). Lead co-reported drug Bedinvetmab (90).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 437
Cat 37
Horse 5
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 52
Retriever - Labrador 46
Retriever - Golden 25
Boxer (German Boxer) 19
Shepherd Dog - German 17
Chihuahua 15
Domestic Shorthair 15
Pit Bull 12
Domestic (unspecified) 12
Terrier - Yorkshire 11

Associated Drugs

Bedinvetmab 90
Carprofen 79
Gabapentin 31
Spinosad 27
Afoxolaner 26
Grapiprant 25
Milbemycin Oxime + Spinosad 24
Maropitant Citrate 21
Melarsomine Dihydrochloride 20
Moxidectin 15
Deracoxib 14
Meloxicam 12
Firocoxib 12
Melarsomine Dihydrochloride Injection 11
Tramadol 10
Polysulfated Glycosaminoglycan 10
Ivermectin 9
Trazodone 9
Frunevetmab 9
Selamectin 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Proprioception abnormality, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (480 here).

Similar death-coded share

Nearest other reactions by death-coded share (20.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Proprioception abnormality (#657 of 2,481 by report volume); death-coded 20.8%. PlainBreed reaction plate · death-coded report count stamp 100 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →