Reaction profile

The FDA adverse-event record for wheal

112 FDA adverse-event reports reference wheal (VeDDRA 520). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1337 of 2,481
by report volume (all reactions)
112
reports citing this reaction
0.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Wheal has 112 reports now versus 111 in that prior snapshot: 1 more (0.9%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Wheal changes

FDA AER · VeDDRA plate

Code 520 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 112 reports
  • DEATH-RARE 0.9%
  • MID-PACK #1337/2481
  • PHOTO-FINISH Broken components, me…
  • SPECIES-DOG Dog · 100
  • DRUG-LEAD Moxidectin · 24
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Broken components, medical device (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Wheal

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Broken components, me… · near112Eyelid erythema · near112Wheal · this reaction112Asthma · near111Counterfeit product · near111Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Wheal

Wheal: low death-coded share in the FDA AER plate

Signature read: Wheal's 0.9% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 1 of 112 reports (0.9% of named reports). Nearest volume peer: Broken components, medical device (±0 reports). Lead species Dog (100). Lead co-reported drug Moxidectin (24).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 100
Horse 7
Cat 2
Cattle 2
Human 1

Breeds Most Affected

Terrier - Bull - American Pit 10
Retriever - Labrador 9
Chihuahua 8
Dachshund (unspecified) 6
Boxer (German Boxer) 5
Crossbred Canine/dog 4
Terrier - Rat 3
Terrier (unspecified) 3
Terrier - Boston 3
Terrier - Bull - Staffordshire 3

Associated Drugs

Moxidectin 24
Oclacitinib Maleate 11
Anti-Il31 Mab Mcs Lot #1283563 9
Afoxolaner 7
Maropitant Citrate 7
Prednisone 7
Imidacloprid + Moxidectin 5
Spinosad 5
Cefovecin 5
Milbemycin Oxime + Spinosad 5
Fluralaner Chew Tablets 5
Cephalexin 5
Hyaluronate Sodium 3
Pentosan 3
Cyclosporine A 3
Ivermectin + Pyrantel Pamoate 3
Melarsomine Dihydrochloride Injection 3
Diphenhydramine 3
Metronidazole 3
Carprofen 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Wheal, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (112 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Wheal (#1337 of 2,481 by report volume); death-coded 0.9%. PlainBreed reaction plate · death-coded share stamp 0.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →