Reaction profile

The FDA adverse-event record for polychromasia

Name: POLYCHROMASIA - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

43 FDA reports name polychromasia, a lower-volume reaction in the CVM extract (VeDDRA 99337). Plate stamps and neighbourhood peers follow.

#1820 of 2,481
by report volume (all reactions): 43
reports citing this reaction: 30.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. POLYCHROMASIA has 43 reports now versus 43 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to POLYCHROMASIA changes

FDA AER · VeDDRA plate

Code 99337 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 43 reports
DEATH-HOT 30.2%
MID-PACK #1820/2481
PHOTO-FINISH Application site numb…
SPECIES-DOG Dog · 40
DRUG-LEAD Carprofen · 7
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Application site numbness (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around POLYCHROMASIA

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around POLYCHROMASIA

POLYCHROMASIA: high death-coded share in the FDA AER plate

Signature read: POLYCHROMASIA's 30.2% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 43 named reports in the openFDA extract. Death-coded share is upper-third: 13 of 43 reports (30.2% of named reports). Nearest volume peer: Application site numbness (±0 reports). Lead species Dog (40). Lead co-reported drug Carprofen (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 40

Cat 3

Breeds Most Affected

Beagle 4

Crossbred Canine/dog 4

Terrier - West Highland White 3

Terrier - Yorkshire 2

Retriever - Labrador 2

Schnauzer (unspecified) 2

Domestic (unspecified) 2

Dachshund (unspecified) 2

Shepherd Dog - German 2

Retriever - Golden 2

Associated Drugs

Carprofen 7

Cyclosporine 5

Trilostane 5

Moxidectin 4

Cefovecin Sodium 3

Spinosad 3

Milbemycin Oxime + Spinosad 3

Meloxicam 2

Melarsomine Dihydrochloride 2

Selamectin 2

Deracoxib 2

Firocoxib 2

Cefovecin 2

Ivermectin + Pyrantel As Pamoate Salt 2

Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 2

Pimobendan 1

Glucosamine 1

Robenacoxib 1

Buprenorphine 1

Prednisone 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for POLYCHROMASIA (#1820 of 2,481 by report volume); death-coded 30.2%. PlainBreed reaction plate · death-coded share stamp 30.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →