Reaction profile

The FDA adverse-event record for polychromasia

43 FDA adverse-event reports reference polychromasia (VeDDRA 99337). See the species, breeds, and drugs most associated with it below.

43
reports citing this reaction
30.2%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
43
Total Reports
13
Deaths
30.2%
Death Rate

Species Most Affected

Dog 40
Cat 3

Breeds Most Affected

Beagle 4
Crossbred Canine/dog 4
Terrier - West Highland White 3
Terrier - Yorkshire 2
Retriever - Labrador 2
Domestic (unspecified) 2
Schnauzer (unspecified) 2
Dachshund (unspecified) 2
Shepherd Dog - German 2
Retriever - Golden 2

Associated Drugs

Carprofen 7
Cyclosporine 5
Trilostane 5
Moxidectin 4
Cefovecin Sodium 3
Spinosad 3
Milbemycin Oxime + Spinosad 3
Meloxicam 2
Melarsomine Dihydrochloride 2
Selamectin 2
Deracoxib 2
Firocoxib 2
Cefovecin 2
Ivermectin + Pyrantel As Pamoate Salt 2
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 2
Pimobendan 1
Glucosamine 1
Robenacoxib 1
Buprenorphine 1
Prednisone 1

POLYCHROMASIA Reaction Insights

43 reports name POLYCHROMASIA; 13 recorded a death outcome (30.2% of reported events, not a population-level mortality rate). VeDDRA code: 99337.

By species: Dog (40 reports), Cat (3 reports). By breed: Beagle (4), Crossbred Canine/dog (4), Terrier - West Highland White (3).

Most co-reported drugs: Carprofen (7 reports), Cyclosporine (5 reports), Trilostane (5 reports), Moxidectin (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.