Dental calculus
VeDDRA Code: 2226
411 adverse event reports referencing this reaction
411
Total Reports
60
Deaths
1460.0%
Death Rate
Species Most Affected
Dog 373
Cat 38
Breeds Most Affected
Retriever - Labrador 46
Crossbred Canine/dog 24
Domestic Shorthair 23
Shih Tzu 20
Chihuahua 18
Maltese 17
Retriever - Golden 15
Pit Bull 14
Terrier - Jack Russell 12
Shepherd Dog - German 11
Associated Drugs
Milbemycin Oxime + Spinosad 197
Milbemycin Oxime + Praziquantel 49
Trilostane 47
Rabies Vaccine 34
Spinosad 24
Bordetella Vaccine 23
Maropitant Citrate 22
Afoxolaner 21
Fluralaner Chew Tablets 17
Gabapentin 17
Carprofen 15
Ivermectin 15
Imidacloprid + Moxidectin 14
Prednisone 14
Milbemycin Oxime 13
Oclacitinib Maleate 13
Lotilaner 13
Tramadol 12
Fluralaner 12
Cyclosporine 10
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.