Reaction profile

The FDA adverse-event record for potency, high

77 FDA adverse-event reports reference potency, high (VeDDRA 99019). See the species, breeds, and drugs most associated with it below.

77
reports citing this reaction
11.7%
death-coded share
Unknown
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
77
Total Reports
9
Deaths
11.7%
Death Rate

Species Most Affected

Unknown 58
Dog 10
Cattle 4
Cat 3
Horse 2

Breeds Most Affected

Unknown 60
Holstein-Friesian also known as Holstein 2
Dog (unknown) 2
Spaniel - King Charles Cavalier 2
Aberdeen Angus 1
Beagle 1
Cattle (unknown) 1
Domestic Shorthair 1
Terrier - Fox Wire 1
Mixed (Dog) 1

Associated Drugs

Monensin Sodium 7
Porcine Insulin 5
Bambermycins 4
Cyclosporine 3
Melengestrol Acetate 2
Virginiamycin 2
Tiamulin Hydrogen Fumarate 2
Robenidine Hydrochloride 2
Clindamycin Hydrochloride 2
Chlortetracycline 2
Insulin Human 2
Pyrimethamine + Toltrazuril 2
Methimazole 2
Fluralaner 5.46% 1-Month Chew 2
Betamethasone Valerate + Gentamicin 2
Neomycin Sulfate, Nystatin, Thiostrepton, Triamcinolone Acetonide 1
Isoflurane 1
Moxidectin 1
Device: Skin Stapler/Staples 1
Narasin 1

Potency, High Reaction Insights

77 reports name Potency, High; 9 recorded a death outcome (11.7% of reported events, not a population-level mortality rate). VeDDRA code: 99019.

By species: Unknown (58 reports), Dog (10 reports), Cattle (4 reports). By breed: Unknown (60), Holstein-Friesian also known as Holstein (2), Dog (unknown) (2).

Most co-reported drugs: Monensin Sodium (7 reports), Porcine Insulin (5 reports), Bambermycins (4 reports), Cyclosporine (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.