Reaction profile

The FDA adverse-event record for potency, high

81 FDA adverse-event reports reference potency, high (VeDDRA 99019). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1495 of 2,481
by report volume (all reactions)
81
reports citing this reaction
11.1%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Potency, High has 81 reports now versus 80 in that prior snapshot: 1 more (1.3%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Potency, High changes

FDA AER · VeDDRA plate

Code 99019 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 81 reports
  • DEATH-ELEV 11.1%
  • MID-PACK #1495/2481
  • PHOTO-FINISH Hissing
  • SPECIES-UNKNOWN Unknown · 62
  • DRUG-LEAD Monensin Sodium · 7
  • DESK-WIDE 15 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hissing (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Potency, High

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Blepharitis · near82Hissing · near81INEFFECTIVE, NEOPLASIA · near81Potency, High · this reaction81Wrong strength dispen… · near81Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Potency, High

What the FDA AER plate says about Potency, High

Signature read: 9 death-coded reports is the most distinctive absolute-outcome stamp on Potency, High. Report volume sits in the middle third of the reaction corpus. 9 of 81 reports were death-coded (11.1% of named reports, not a population mortality rate). Nearest volume peer: Hissing (±0 reports). Lead species Unknown (62). Lead co-reported drug Monensin Sodium (7).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Monensin Sodium appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 62
Dog 10
Cattle 4
Cat 3
Horse 2

Breeds Most Affected

Unknown 64
Holstein-Friesian also known as Holstein 2
Dog (unknown) 2
Spaniel - King Charles Cavalier 2
Beagle 1
Aberdeen Angus 1
Cattle (unknown) 1
Domestic Shorthair 1
Terrier - Fox Wire 1
Mixed (Dog) 1

Associated Drugs

Monensin Sodium 7
Porcine Insulin 5
Bambermycins 4
Cyclosporine 3
Melengestrol Acetate 2
Virginiamycin 2
Tiamulin Hydrogen Fumarate 2
Robenidine Hydrochloride 2
Clindamycin Hydrochloride 2
Phenobarbital 2
Chlortetracycline 2
Insulin Human 2
Methimazole 2
Pyrimethamine + Toltrazuril 2
Fluralaner 5.46% 1-Month Chew 2
Betamethasone Valerate + Gentamicin 2
Neomycin Sulfate, Nystatin, Thiostrepton, Triamcinolone Acetonide 1
Isoflurane 1
Moxidectin 1
Device: Skin Stapler/Staples 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Potency, High, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (81 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Potency, High (#1495 of 2,481 by report volume); death-coded 11.1%. PlainBreed reaction plate · death-coded report count stamp 9 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →