Reaction profile

The FDA adverse-event record for residues in milk

377 FDA reports name residues in milk, a high-volume reaction in the CVM extract (VeDDRA 2043). Plate stamps and neighbourhood peers follow.

#764 of 2,481
by report volume (all reactions)
377
reports citing this reaction
1.3%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Residues in milk has 377 reports now versus 375 in that prior snapshot: 2 more (0.5%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Residues in milk changes

FDA AER · VeDDRA plate

Code 2043 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 377 reports
  • DEATH-LOW 1.3%
  • MID-PACK #764/2481
  • PHOTO-FINISH Abnormal test result
  • SPECIES-CATTLE Cattle · 371
  • DRUG-LEAD Cephapirin Sodium · 180
  • DESK-WIDE 12 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal test result (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Residues in milk

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Increased drinking · near378Abnormal test result · near377Cellulitis · near377Residues in milk · this reac…377Weight fluctuation · near377Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Residues in milk

Residues in milk: low death-coded share in the FDA AER plate

Signature read: Residues in milk's 1.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 377 named reports in the openFDA extract. Death-coded share is lower-third: 5 of 377 reports (1.3% of named reports). Nearest volume peer: Abnormal test result (±0 reports). Lead species Cattle (371). Lead co-reported drug Cephapirin Sodium (180).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Cephapirin Sodium appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 371
Goat 5
Horse 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 191
Cattle (other) 94
Cattle (unknown) 54
Jersey 17
Crossbred Bovine/Cattle 8
Goat (unknown) 4
Brown Swiss 3
Unknown 2
Ayrshire 1
Mixed (Cattle) 1

Associated Drugs

Cephapirin Sodium 180
Ceftiofur Hydrochloride 78
Cephapirin Benzathine 22
Cloxacillin Benzathine 16
Ceftiofur Crystalline Free Acid 15
Ampicillin Trihydrate 13
Cloxacillin Benz Intramam Dc 13
Ceftiofur 10
Tulathromycin 9
Dihydrostreptomycin, Penicillin G Procaine 6
Ceftiofur Sodium 5
Hetacillin Potassium 5
Pirlimycin Hydrochloride 4
Penicillin G Procaine 2
Doramectin 2
Pirlimycin 2
Eprinomectin 2
Ampicillin 2
Dinoprost Tromethamine 1
Oxytetracycline 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Residues in milk, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (377 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Residues in milk (#764 of 2,481 by report volume); death-coded 1.3%. PlainBreed reaction plate · death-coded share stamp 1.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →