Reaction profile

The FDA adverse-event record for squinting

826 FDA reports name squinting, a high-volume reaction in the CVM extract (VeDDRA 2235). Plate stamps and neighbourhood peers follow.

#451 of 2,481
by report volume (all reactions)
826
reports citing this reaction
3.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Squinting has 826 reports now versus 810 in that prior snapshot: 16 more (2.0%).

Report change
+16
Death-coded reports
+2
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Squinting changes

FDA AER · VeDDRA plate

Code 2235 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 826 reports
  • DEATH-LOW 3.5%
  • UPPER-Q #451/2481
  • PHOTO-FINISH Abdominal discomfort
  • SPECIES-DOG Dog · 572
  • DRUG-LEAD Florfenicol + Mom… · 144
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal discomfort (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Squinting

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hepatomegaly · near827Squinting · this reaction826Abdominal discomfort · near825Increased appetite · near825Decreased bowel movem… · near821Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Squinting

Squinting: low death-coded share in the FDA AER plate

Signature read: 826 reports place Squinting in the upper third of FDA AER volume (#451 of 2,481). Report volume is upper-third scale: 826 named reports in the openFDA extract. Death-coded share is lower-third: 29 of 826 reports (3.5% of named reports). Nearest volume peer: Abdominal discomfort (±1 reports). Lead species Dog (572). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (144).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 572
Cat 248
Cattle 5
Human 1

Breeds Most Affected

Domestic Shorthair 134
Chihuahua 70
Crossbred Canine/dog 38
Shih Tzu 34
Retriever - Golden 31
Retriever - Labrador 30
Domestic Longhair 30
Terrier - Yorkshire 28
Cat (unknown) 19
Domestic Mediumhair 18

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 144
Milbemycin Oxime + Spinosad 100
Maropitant Citrate 52
Imidacloprid + Moxidectin 46
Spinosad 44
Prednisone 30
Gabapentin 30
Oclacitinib Maleate 28
Selamectin;Sarolaner 28
Carprofen 26
Afoxolaner 24
Pilocarpine 24
Cyclosporine 22
Fluralaner Spot-On Solution 22
Selamectin 21
Ear Cleaner 19
Lotilaner 19
Meloxicam 18
Milbemycin Oxime + Praziquantel 18
Moxidectin 17

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Squinting, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (826 here).

Similar death-coded share

Nearest other reactions by death-coded share (3.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Squinting (#451 of 2,481 by report volume); death-coded 3.5%. PlainBreed reaction plate · report volume stamp 826 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →