Reaction profile

The FDA adverse-event record for squinting

784 FDA adverse-event reports reference squinting (VeDDRA 2235). See the species, breeds, and drugs most associated with it below.

784
reports citing this reaction
2.9%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
784
Total Reports
23
Deaths
2.9%
Death Rate

Species Most Affected

Dog 540
Cat 238
Cattle 5
Human 1

Breeds Most Affected

Domestic Shorthair 125
Chihuahua 69
Crossbred Canine/dog 37
Shih Tzu 32
Domestic Longhair 30
Retriever - Golden 28
Retriever - Labrador 26
Terrier - Yorkshire 25
Cat (unknown) 18
Domestic Mediumhair 18

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 139
Milbemycin Oxime + Spinosad 100
Maropitant Citrate 50
Imidacloprid + Moxidectin 45
Spinosad 44
Prednisone 29
Gabapentin 28
Oclacitinib Maleate 27
Selamectin;Sarolaner 27
Carprofen 25
Cyclosporine 22
Fluralaner Spot-On Solution 22
Pilocarpine 21
Selamectin 20
Afoxolaner 20
Lotilaner 19
Meloxicam 18
Milbemycin Oxime + Praziquantel 18
Moxidectin 17
Betamethasone + Florfenicol + Terbinafine 17

Squinting Reaction Insights

784 reports name Squinting; 23 recorded a death outcome (2.9% of reported events, not a population-level mortality rate). VeDDRA code: 2235.

By species: Dog (540 reports), Cat (238 reports), Cattle (5 reports). By breed: Domestic Shorthair (125), Chihuahua (69), Crossbred Canine/dog (37).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (139 reports), Milbemycin Oxime + Spinosad (100 reports), Maropitant Citrate (50 reports), Imidacloprid + Moxidectin (45 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.