Reaction profile

The FDA adverse-event record for cardiomyopathy

283 FDA adverse-event reports reference cardiomyopathy (VeDDRA 205). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#893 of 2,481
by report volume (all reactions)
283
reports citing this reaction
62.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cardiomyopathy has 283 reports now versus 275 in that prior snapshot: 8 more (2.9%).

Report change
+8
Death-coded reports
+2
Death-coded share
−1.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cardiomyopathy changes

FDA AER · VeDDRA plate

Code 205 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 283 reports
  • DEATH-HOT 62.9%
  • MID-PACK #893/2481
  • PHOTO-FINISH Cognitive disorder NOS
  • SPECIES-DOG Dog · 149
  • DRUG-LEAD Spinosad · 34
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cognitive disorder NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Cardiomyopathy

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiomyopathy · this reacti…283Cognitive disorder NOS · near283Injection site serosa… · near283Lack of efficacy (fun… · near283Peeling skin · near283Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Cardiomyopathy

Cardiomyopathy: high death-coded share in the FDA AER plate

Signature read: Cardiomyopathy's 62.9% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 178 of 283 reports (62.9% of named reports). Nearest volume peer: Cognitive disorder NOS (±0 reports). Lead species Dog (149). Lead co-reported drug Spinosad (34).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 149
Cat 120
Cattle 8
Chicken 4
Turkey 1
Deer 1

Breeds Most Affected

Domestic Shorthair 75
Doberman Pinscher 16
Domestic Longhair 15
Boxer (German Boxer) 14
Retriever - Labrador 8
Retriever - Golden 7
Crossbred Canine/dog 6
Chihuahua 5
Siamese 5
Maltese 5

Associated Drugs

Spinosad 34
Maropitant Citrate 29
Milbemycin Oxime + Spinosad 28
Buprenorphine 20
Cefovecin 19
Robenacoxib 14
Cyclosporine 14
Gabapentin 14
Trilostane 11
Afoxolaner 11
Cefovecin Sodium 10
Isoflurane 10
Oclacitinib Maleate 10
Fluralaner Spot-On Solution 10
Moxidectin 9
Fluralaner Chew Tablets 9
Propofol 9
Enrofloxacin 8
Furosemide 8
Ivermectin + Pyrantel As Pamoate Salt 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Cardiomyopathy, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (62.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cardiomyopathy (#893 of 2,481 by report volume); death-coded 62.9%. PlainBreed reaction plate · death-coded share stamp 62.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →