Reaction profile

The FDA adverse-event record for corneal disorder nos

396 FDA reports name corneal disorder nos, a high-volume reaction in the CVM extract (VeDDRA 412). Plate stamps and neighbourhood peers follow.

#732 of 2,481
by report volume (all reactions)
396
reports citing this reaction
9.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Corneal disorder NOS has 396 reports now versus 390 in that prior snapshot: 6 more (1.5%).

Report change
+6
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Corneal disorder NOS changes

FDA AER · VeDDRA plate

Code 412 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 396 reports
  • DEATH-PAR 9.3%
  • MID-PACK #732/2481
  • PHOTO-FINISH Hearing decreased
  • SPECIES-DOG Dog · 341
  • DRUG-LEAD Florfenicol + Mom… · 84
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hearing decreased (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Corneal disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Elevated protein:crea… · near397Polycythaemia · near397Corneal disorder NOS · this …396Hearing decreased · near396Lumbar pain · near396Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Corneal disorder NOS

What the FDA AER plate says about Corneal disorder NOS

Signature read: 396 reports place Corneal disorder NOS in the upper third of FDA AER volume (#732 of 2,481). Report volume is upper-third scale: 396 named reports in the openFDA extract. 37 of 396 reports were death-coded (9.3% of named reports, not a population mortality rate). Nearest volume peer: Hearing decreased (±0 reports). Lead species Dog (341). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (84).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 341
Cat 34
Human 9
Cattle 8
Goat 2
Guinea Pig 1
Horse 1

Breeds Most Affected

Shih Tzu 40
Chihuahua 35
Crossbred Canine/dog 22
Domestic Shorthair 20
Retriever - Labrador 14
Unknown 13
Shepherd Dog - German 11
Maltese 10
Dog (unknown) 10
Terrier - Yorkshire 10

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 84
Carprofen 37
Maropitant Citrate 31
Cyclosporine 29
Milbemycin Oxime + Spinosad 28
Prednisone 28
Oclacitinib Maleate 28
Ofloxacin 27
Tobramycin 25
Pilocarpine 25
Meloxicam 20
Ear Cleaner 20
Gabapentin 20
Artificial Tears 18
Enrofloxacin 17
Grapiprant 17
Afoxolaner 16
Trilostane 14
Bordetella Vaccine 14
Eye Lubricant 13

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Corneal disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (396 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Corneal disorder NOS (#732 of 2,481 by report volume); death-coded 9.3%. PlainBreed reaction plate · report volume stamp 396 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →