Reaction profile

The FDA adverse-event record for cranial nerve paralysis

Name: Cranial nerve paralysis - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

14 FDA reports name cranial nerve paralysis, a lower-volume reaction in the CVM extract (VeDDRA 1150). Plate stamps and neighbourhood peers follow.

#2323 of 2,481
by report volume (all reactions): 14
reports citing this reaction: 21.4%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cranial nerve paralysis has 14 reports now versus 12 in that prior snapshot: 2 more (16.7%).

Report change: +2
Death-coded reports: +2
Death-coded share: +13.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cranial nerve paralysis changes

FDA AER · VeDDRA plate

Code 1150 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 14 reports
DEATH-HOT 21.4%
BOTTOM-DECILE #2323/2481
PHOTO-FINISH Addisonian crisis
SPECIES-DOG Dog · 12
DRUG-LEAD Ivermectin + Pyra… · 2
DESK-WIDE 11 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Addisonian crisis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Cranial nerve paralysis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Cranial nerve paralysis

What the FDA AER plate says about Cranial nerve paralysis

Signature read: 14 reports place Cranial nerve paralysis in the lower third of FDA AER volume (#2323 of 2,481). Report volume is lower-third scale: 14 named reports in the openFDA extract. 3 of 14 reports were death-coded (21.4% of named reports, not a population mortality rate). Nearest volume peer: Addisonian crisis (±0 reports). Lead species Dog (12). Lead co-reported drug Ivermectin + Pyrantel (2).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin + Pyrantel appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 12

Horse 1

Cat 1

Breeds Most Affected

Retriever - Labrador 3

Retriever - Golden 2

Paint 1

Crossbred Canine/dog 1

Terrier - West Highland White 1

Chihuahua 1

Shepherd (unspecified) 1

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Domestic Shorthair 1

Terrier - Bull - Miniature 1

Associated Drugs

Ivermectin + Pyrantel 2

Doxycycline 2

Gabapentin 2

Oxybendazole 1

Milbemycin Oxime + Spinosad 1

Fipronil 1

Fluralaner Chew Tablets 1

Canine B Burgdorferi *2 Alu Kb 1

Canine Lepto*4(Orig S-P Us) Kb 1

Canine Da2Ppv (Orig S-P Us) Lv 1

Milbemycin Oxime 1

Ivermectin 1

Afoxolaner 1

Sarolaner 1

Genta/Momet/Clotrim Ear Oint 1

Trilostane 1

Fluralaner Spot-On Solution 1

Carprofen 1

Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 1

Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cranial nerve paralysis (#2323 of 2,481 by report volume); death-coded 21.4%. PlainBreed reaction plate · report volume stamp 14 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →