Reaction profile

The FDA adverse-event record for pr-thyroid, lesion(s)

27 FDA adverse-event reports reference pr-thyroid, lesion(s) (VeDDRA 99688). See the species, breeds, and drugs most associated with it below.

27
reports citing this reaction
88.9%
death-coded share
Dog
most-affected species
Cefovecin
most-associated drug
Verify with FDA CVM →
27
Total Reports
24
Deaths
88.9%
Death Rate

Species Most Affected

Dog 17
Cat 9
Horse 1

Breeds Most Affected

Domestic (unspecified) 4
Domestic Shorthair 4
Crossbred Canine/dog 2
Doberman Pinscher 2
Beagle 2
Retriever - Labrador 2
Boxer (German Boxer) 2
Newfoundland 1
Persian 1
Pointing Dog - Hungarian Short-haired (Vizsla) 1

Associated Drugs

Cefovecin 4
Oclacitinib Maleate 4
Milbemycin Oxime + Spinosad 3
Spinosad 2
Robenacoxib 2
Carprofen 2
Levothyroxine Sodium 2
Fluralaner Chew Tablets 2
Dexmedetomidine Hydrochloride 1
Selamectin 1
Deracoxib 1
Cefovecin Sodium 1
Antibiotic (Unknown) 1
Ticarcillin Disodium, Clavulanate Potassium 1
Dexamethasone 1
Food 1
Methimazole 1
Imidacolprid And Moxidectin 1
Methylprednisolone Acetate 1
Dhpp Vaccine 1

PR-THYROID, LESION(S) Reaction Insights

27 reports name PR-THYROID, LESION(S); 24 recorded a death outcome (88.9% of reported events, not a population-level mortality rate). VeDDRA code: 99688.

By species: Dog (17 reports), Cat (9 reports), Horse (1 reports). By breed: Domestic (unspecified) (4), Domestic Shorthair (4), Crossbred Canine/dog (2).

Most co-reported drugs: Cefovecin (4 reports), Oclacitinib Maleate (4 reports), Milbemycin Oxime + Spinosad (3 reports), Spinosad (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.