Reaction profile

The FDA adverse-event record for decreased skin turgor

44 FDA adverse-event reports reference decreased skin turgor (VeDDRA 2549). See the species, breeds, and drugs most associated with it below.

44
reports citing this reaction
29.5%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
44
Total Reports
13
Deaths
29.5%
Death Rate

Species Most Affected

Dog 30
Cat 13
Horse 1

Breeds Most Affected

Domestic Shorthair 13
Retriever - Labrador 5
Pit Bull 3
Pug 2
Beagle 2
American Pit Bull Terrier 2
Spaniel - King Charles Cavalier 2
Bulldog - French 2
Terrier (unspecified) 1
Collie - Smooth-haired 1

Associated Drugs

Carprofen 9
Maropitant 8
Rabies Vaccine 8
Buprenorphine 7
Diphenhydramine 7
Maropitant Citrate 6
Famotidine 6
Gabapentin 6
Butorphanol 5
Afoxolaner 4
Ondansetron 4
Firocoxib 4
Enrofloxacin 4
Tigilanol Tiglate 4
Robenacoxib 3
Cefazolin 3
Sodium Chloride 3
Prednisone 3
Midazolam 2
Prednisolone 2

Decreased skin turgor Reaction Insights

44 reports name Decreased skin turgor; 13 recorded a death outcome (29.5% of reported events, not a population-level mortality rate). VeDDRA code: 2549.

By species: Dog (30 reports), Cat (13 reports), Horse (1 reports). By breed: Domestic Shorthair (13), Retriever - Labrador (5), Pit Bull (3).

Most co-reported drugs: Carprofen (9 reports), Maropitant (8 reports), Rabies Vaccine (8 reports), Buprenorphine (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.