Facial pruritus

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VeDDRA Code: 2877

313 adverse event reports referencing this reaction

313
Total Reports
8
Deaths
260.0%
Death Rate

Species Most Affected

Cat 209
Dog 99
Horse 2
Donkey 1
Bat 1
Human 1

Breeds Most Affected

Domestic Shorthair 147
Domestic Longhair 27
Cat (other) 12
Retriever - Labrador 10
Domestic Mediumhair 10
Siberian Husky 7
Shepherd Dog - German 7
Retriever - Golden 7
Terrier - Yorkshire 6
Crossbred Canine/dog 5

Associated Drugs

Frunevetmab 179
Moxidectin 39
Thiamazole 15
Cefovecin 14
Methimazole 14
Prednisolone 13
Bedinvetmab 12
Gabapentin 11
Maropitant Citrate 9
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 9
Anti-Il31 Mab Mcs Lot #1283563 8
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 8
Rabies Vaccine 8
Selamectin;Sarolaner 8
Rabies Virus, Kv 8
Diphenhydramine 6
Selamectin 6
Trilostane 5
Pyrantel Pamoate;Sarolaner 5
Melarsomine Dihydrochloride 4

Data Summary

Metric Value
Total reports referencing reaction 313
Reports with fatal outcome 8
Case-fatality rate (reported events) 260.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2877.

Facial pruritus Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 313 adverse event reports that reference Facial pruritus as a reaction term, including 8 reports with a death outcome — a 260.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2877, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Facial pruritus appears most frequently in reports for Cat (209 reports), Dog (99 reports), Horse (2 reports) — with Cat dominating at 209 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (147), Domestic Longhair (27), Cat (other) (12). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Facial pruritus are Frunevetmab (179 reports), Moxidectin (39 reports), Thiamazole (15 reports), Cefovecin (14 reports), with Frunevetmab appearing alongside this reaction in 179 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial