Reaction profile

The FDA adverse-event record for facial pruritus

313 FDA adverse-event reports reference facial pruritus (VeDDRA 2877). See the species, breeds, and drugs most associated with it below.

313
reports citing this reaction
2.6%
death-coded share
Cat
most-affected species
Frunevetmab
most-associated drug
Verify with FDA CVM →
313
Total Reports
8
Deaths
2.6%
Death Rate

Species Most Affected

Cat 209
Dog 99
Horse 2
Donkey 1
Bat 1
Human 1

Breeds Most Affected

Domestic Shorthair 147
Domestic Longhair 27
Cat (other) 12
Retriever - Labrador 10
Domestic Mediumhair 10
Siberian Husky 7
Shepherd Dog - German 7
Retriever - Golden 7
Terrier - Yorkshire 6
Crossbred Canine/dog 5

Associated Drugs

Frunevetmab 179
Moxidectin 39
Thiamazole 15
Cefovecin 14
Methimazole 14
Prednisolone 13
Bedinvetmab 12
Gabapentin 11
Maropitant Citrate 9
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 9
Anti-Il31 Mab Mcs Lot #1283563 8
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 8
Rabies Vaccine 8
Selamectin;Sarolaner 8
Rabies Virus, Kv 8
Diphenhydramine 6
Selamectin 6
Trilostane 5
Pyrantel Pamoate;Sarolaner 5
Melarsomine Dihydrochloride 4

Facial pruritus Reaction Insights

313 reports name Facial pruritus; 8 recorded a death outcome (2.6% of reported events, not a population-level mortality rate). VeDDRA code: 2877.

By species: Cat (209 reports), Dog (99 reports), Horse (2 reports). By breed: Domestic Shorthair (147), Domestic Longhair (27), Cat (other) (12).

Most co-reported drugs: Frunevetmab (179 reports), Moxidectin (39 reports), Thiamazole (15 reports), Cefovecin (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.