Reaction profile

The FDA adverse-event record for peritoneal haemorrhage

39 FDA adverse-event reports reference peritoneal haemorrhage (VeDDRA 2101). See the species, breeds, and drugs most associated with it below.

39
reports citing this reaction
84.6%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
39
Total Reports
33
Deaths
84.6%
Death Rate

Species Most Affected

Dog 32
Cat 6
Cattle 1

Breeds Most Affected

Retriever - Labrador 6
Domestic Shorthair 4
Crossbred Canine/dog 3
Boxer (German Boxer) 3
Dachshund (unspecified) 3
Shepherd Dog - German 2
Rottweiler 2
Weimaraner 2
Spaniel - Cocker English 1
Leonberger 1

Associated Drugs

Milbemycin Oxime + Spinosad 10
Carprofen 7
Ivermectin 4
Spinosad 3
Polysulfated Glycosaminoglycan 3
Robenacoxib 3
Gabapentin 3
Rabies Vaccine 2
Firocoxib 2
Oclacitinib Maleate 2
Deracoxib 2
Tramadol 2
Moxidectin 2
Melarsomine Dihydrochloride 2
Doxycycline 2
Fluralaner 2
Ketamine Hydrochloride 2
Diphenhydramine 2
Pyrantel Pamoate 2
Bedinvetmab 2

Peritoneal haemorrhage Reaction Insights

39 reports name Peritoneal haemorrhage; 33 recorded a death outcome (84.6% of reported events, not a population-level mortality rate). VeDDRA code: 2101.

By species: Dog (32 reports), Cat (6 reports), Cattle (1 reports). By breed: Retriever - Labrador (6), Domestic Shorthair (4), Crossbred Canine/dog (3).

Most co-reported drugs: Milbemycin Oxime + Spinosad (10 reports), Carprofen (7 reports), Ivermectin (4 reports), Spinosad (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.