Reaction profile

The FDA adverse-event record for peritoneal haemorrhage

42 FDA reports name peritoneal haemorrhage, a lower-volume reaction in the CVM extract (VeDDRA 2101). Plate stamps and neighbourhood peers follow.

#1833 of 2,481
by report volume (all reactions)
42
reports citing this reaction
83.3%
death-coded share
Dog
most-affected species
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Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Peritoneal haemorrhage has 42 reports now versus 40 in that prior snapshot: 2 more (5.0%).

Report change
+2
Death-coded reports
+1
Death-coded share
−1.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Peritoneal haemorrhage changes

FDA AER · VeDDRA plate

Code 2101 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 42 reports
  • DEATH-HOT 83.3%
  • MID-PACK #1833/2481
  • PHOTO-FINISH Allergy to food
  • SPECIES-DOG Dog · 35
  • DRUG-LEAD Milbemycin Oxime… · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Allergy to food (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Peritoneal haemorrhage

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Allergy to food · near42Asystole · near42Cholecystitis · near42Cutaneous emphysema · near42Peritoneal haemorrhage · thi…42Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Peritoneal haemorrhage

Peritoneal haemorrhage: high death-coded share in the FDA AER plate

Signature read: Peritoneal haemorrhage's 83.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 42 named reports in the openFDA extract. Death-coded share is upper-third: 35 of 42 reports (83.3% of named reports). Nearest volume peer: Allergy to food (±0 reports). Lead species Dog (35). Lead co-reported drug Milbemycin Oxime + Spinosad (10).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 35
Cat 6
Cattle 1

Breeds Most Affected

Retriever - Labrador 7
Crossbred Canine/dog 4
Domestic Shorthair 4
Dachshund (unspecified) 3
Boxer (German Boxer) 3
Shepherd Dog - German 2
Rottweiler 2
Weimaraner 2
Spaniel - Cocker English 1
Leonberger 1

Associated Drugs

Milbemycin Oxime + Spinosad 10
Carprofen 7
Ivermectin 4
Gabapentin 4
Spinosad 3
Polysulfated Glycosaminoglycan 3
Robenacoxib 3
Rabies Vaccine 2
Firocoxib 2
Oclacitinib Maleate 2
Deracoxib 2
Tramadol 2
Moxidectin 2
Melarsomine Dihydrochloride 2
Doxycycline 2
Fluralaner 2
Ketamine Hydrochloride 2
Diphenhydramine 2
Pyrantel Pamoate 2
Bedinvetmab 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Peritoneal haemorrhage (#1833 of 2,481 by report volume); death-coded 83.3%. PlainBreed reaction plate · death-coded share stamp 83.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →