Reaction profile

The FDA adverse-event record for decreased red blood cell count

1,394 FDA reports name decreased red blood cell count, a high-volume reaction in the CVM extract (VeDDRA 2157). Plate stamps and neighbourhood peers follow.

#304 of 2,481
by report volume (all reactions)
1,394
reports citing this reaction
30.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased red blood cell count has 1,394 reports now versus 1,341 in that prior snapshot: 53 more (4.0%).

Report change
+53
Death-coded reports
+11
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased red blood cell count changes

FDA AER · VeDDRA plate

Code 2157 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,394 reports
  • DEATH-HOT 30.6%
  • UPPER-Q #304/2481
  • PHOTO-FINISH Tarry or black stool…
  • SPECIES-DOG Dog · 1,152
  • DRUG-LEAD Maropitant Citrate · 122
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tarry or black stool (see also haemorrhagic diarrhoea) (±2 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Decreased red blood cell count

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Self trauma · near1400Tarry or black stool… · near1396Wobbliness · near1396Decreased red blood c… · thi…1394Glucosuria · near1391Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased red blood cell count

Decreased red blood cell count: high death-coded share in the FDA AER plate

Signature read: 426 death-coded reports is a heavy tail count for Decreased red blood cell count in the CVM extract. Report volume is upper-third scale: 1,394 named reports in the openFDA extract. Death-coded share is upper-third: 426 of 1,394 reports (30.6% of named reports). Nearest volume peer: Tarry or black stool (see also haemorrhagic diarrhoea) (±2 reports). Lead species Dog (1,152). Lead co-reported drug Maropitant Citrate (122).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,152
Cat 219
Horse 20
Ferret 1
Donkey 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 161
Domestic Shorthair 146
Crossbred Canine/dog 83
Retriever - Golden 67
Shepherd Dog - German 56
Chihuahua 44
Shih Tzu 37
Pit Bull 31
Maltese 25
Terrier (unspecified) 25

Associated Drugs

Maropitant Citrate 122
Carprofen 117
Prednisone 112
Fluralaner Chew Tablets 103
Ilunocitinib 90
Afoxolaner 89
Oclacitinib Maleate 89
Trilostane 79
Milbemycin Oxime + Spinosad 65
Gabapentin 62
Doxycycline 61
Ivermectin + Pyrantel As Pamoate Salt 59
Enrofloxacin 54
Famotidine 49
Moxidectin 48
Cefovecin 47
Bedinvetmab 44
Metronidazole 41
Fluralaner 13.64% 12-Week Chew 41
Meloxicam 40

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased red blood cell count, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (30.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased red blood cell count (#304 of 2,481 by report volume); death-coded 30.6%. PlainBreed reaction plate · death-coded report count stamp 426 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →