Reaction profile

The FDA adverse-event record for lack of efficacy (protozoa) - giardia

536 FDA adverse-event reports reference lack of efficacy (protozoa) - giardia (VeDDRA 2806). See the species, breeds, and drugs most associated with it below.

536
reports citing this reaction
0.4%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
536
Total Reports
2
Deaths
0.4%
Death Rate

Species Most Affected

Dog 521
Cat 15

Breeds Most Affected

Retriever - Labrador 90
Retriever - Golden 48
Crossbred Canine/dog 23
Shepherd Dog - Australian 20
Shepherd Dog - German 19
Beagle 16
Dog (unknown) 15
Mountain Dog - Bernese 15
Bulldog - French 11
Terrier (unspecified) 11

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 174
Milbemycin Oxime + Praziquantel 121
Pyrantel Pamoate;Sarolaner 77
Fenbendazol Granules 37
Milbemycin/Lufenuron/Pzq Chew 27
Moxidectin 22
Fenbendazole 19
Lotilaner 16
Afoxolaner 14
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 14
Metronidazole 13
Ivermectin + Pyrantel 12
Eprinomectin + Esafoxolaner + Praziquantel 10
Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet 10
Febantel + Praziquantel + Pyrantel Pamoate 9
Imidacloprid + Moxidectin 9
Afoxolaner 18.75Mg / Moxidectin 90Mcg / Pyrantel 37.5Mg Chewable Tablet 9
Fenbendazol Suspension 8
Milbemycin/Lufenuron Tablets 8
Afoxolaner 37.5Mg / Moxidectin 180Mcg / Pyrantel 75Mg Chewable Tablet 8

Lack of efficacy (protozoa) - Giardia Reaction Insights

536 reports name Lack of efficacy (protozoa) - Giardia; 2 recorded a death outcome (0.4% of reported events, not a population-level mortality rate). VeDDRA code: 2806.

By species: Dog (521 reports), Cat (15 reports). By breed: Retriever - Labrador (90), Retriever - Golden (48), Crossbred Canine/dog (23).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (174 reports), Milbemycin Oxime + Praziquantel (121 reports), Pyrantel Pamoate;Sarolaner (77 reports), Fenbendazol Granules (37 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.