Urinary tract disorder NOS

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VeDDRA Code: 739

920 adverse event reports referencing this reaction

920
Total Reports
131
Deaths
1420.0%
Death Rate

Species Most Affected

Dog 694
Cat 215
Horse 8
Unknown 1
Cattle 1
Rabbit 1

Breeds Most Affected

Crossbred Canine/dog 89
Domestic Shorthair 85
Retriever - Labrador 83
Domestic (unspecified) 53
Dog (unknown) 30
Retriever - Golden 29
Shepherd Dog - German 23
Terrier - Yorkshire 22
Boxer (German Boxer) 22
Shih Tzu 19

Associated Drugs

Carprofen 114
Milbemycin Oxime + Spinosad 90
Spinosad 56
Oclacitinib Maleate 43
Meloxicam 40
Selamectin 31
Trilostane 31
Deracoxib 29
Afoxolaner 29
Cyclosporine 26
Cefovecin 24
Milbemycin Oxime + Praziquantel 23
Prednisone 22
Ivermectin + Pyrantel As Pamoate Salt 21
Moxidectin 20
Maropitant Citrate 20
Gabapentin 18
Robenacoxib 17
Bedinvetmab 17
Cyclosporine A 16

Data Summary

Metric Value
Total reports referencing reaction 920
Reports with fatal outcome 131
Case-fatality rate (reported events) 1420.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 739.

Urinary tract disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 920 adverse event reports that reference Urinary tract disorder NOS as a reaction term, including 131 reports with a death outcome — a 1420.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 739, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Urinary tract disorder NOS appears most frequently in reports for Dog (694 reports), Cat (215 reports), Horse (8 reports) — with Dog dominating at 694 entries. Within those species, the breeds most often named alongside this reaction are Crossbred Canine/dog (89), Domestic Shorthair (85), Retriever - Labrador (83). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Urinary tract disorder NOS are Carprofen (114 reports), Milbemycin Oxime + Spinosad (90 reports), Spinosad (56 reports), Oclacitinib Maleate (43 reports), with Carprofen appearing alongside this reaction in 114 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial