Reaction profile

The FDA adverse-event record for immune-mediated polyarthropathy

26 FDA adverse-event reports reference immune-mediated polyarthropathy (VeDDRA 2682). See the species, breeds, and drugs most associated with it below.

26
reports citing this reaction
11.5%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
26
Total Reports
3
Deaths
11.5%
Death Rate

Species Most Affected

Dog 25
Cat 1

Breeds Most Affected

Retriever - Golden 4
Retriever - Labrador 3
Collie - Border 3
Terrier - Bull - American Pit 2
Shih Tzu 2
Shepherd Dog - Australian 2
Boxer (German Boxer) 1
Ridgeback - Rhodesian 1
Unknown 1
Mountain Dog - Bernese 1

Associated Drugs

Carprofen 9
Bedinvetmab 7
Maropitant Citrate 5
Gabapentin 4
Doxycycline 4
Moxidectin 3
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 3
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 3
Amantadine 3
Rabies Virus, Kv 3
Afoxolaner 2
Bordetella Bronchiseptica, Strain 78-9159 2
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2
Prednisone 2
Capromorelin 2
Proviable 2
Pyrantel Pamoate;Sarolaner 2
Entyce 2
Unspecified Fluids 2
Cefovecin 2

Immune-mediated polyarthropathy Reaction Insights

26 reports name Immune-mediated polyarthropathy; 3 recorded a death outcome (11.5% of reported events, not a population-level mortality rate). VeDDRA code: 2682.

By species: Dog (25 reports), Cat (1 reports). By breed: Retriever - Golden (4), Retriever - Labrador (3), Collie - Border (3).

Most co-reported drugs: Carprofen (9 reports), Bedinvetmab (7 reports), Maropitant Citrate (5 reports), Gabapentin (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.