Reaction profile

The FDA adverse-event record for amaurosis (see also pt impaired vision)

18 FDA adverse-event reports reference amaurosis (see also pt impaired vision) (VeDDRA 410). See the species, breeds, and drugs most associated with it below.

18
reports citing this reaction
22.2%
death-coded share
Dog
most-affected species
Ivermectin
most-associated drug
Verify with FDA CVM →
18
Total Reports
4
Deaths
22.2%
Death Rate

Species Most Affected

Dog 15
Rabbit 1
Horse 1
Cat 1

Breeds Most Affected

Terrier - West Highland White 2
Dog (unknown) 2
Lhasa Apso 1
Poodle (unspecified) 1
Crossbred Canine/dog 1
Terrier - Scottish 1
Pinscher - Miniature 1
Rabbit (unknown) 1
Munsterlander - Small 1
Collie - Border 1

Associated Drugs

Ivermectin 3
Milbemycin Oxime + Spinosad 2
Firocoxib 2
Spinosad 2
Enrofloxacin 1
Allergy Shot (Unknown) 1
Loratidine 1
Carprofen 1
Gentamicin + Mometasone + Clotrimazole 1
Antibiotic (Unknown) 1
Ivermectin + Pyrantel Pamoate + Praziquantel 1
Ivermectin 0.5% Pour-On Topical Solution 1
Eprinomectin 5 Mg/Ml Pour-On Solution 1
Ivermectin 10 Mg/Ml Solution For Injection 1
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 1
Orbifloxacin Oral Suspension 1
Nitenpyram 1
Cephalexin 1
Tramadol 1
Carprofen (Unknown) 1

Amaurosis (see also PT Impaired vision) Reaction Insights

18 reports name Amaurosis (see also PT Impaired vision); 4 recorded a death outcome (22.2% of reported events, not a population-level mortality rate). VeDDRA code: 410.

By species: Dog (15 reports), Rabbit (1 reports), Horse (1 reports). By breed: Terrier - West Highland White (2), Dog (unknown) (2), Lhasa Apso (1).

Most co-reported drugs: Ivermectin (3 reports), Milbemycin Oxime + Spinosad (2 reports), Firocoxib (2 reports), Spinosad (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.