Reaction profile

The FDA adverse-event record for disturbance in attention

36 FDA adverse-event reports reference disturbance in attention (VeDDRA 1420). See the species, breeds, and drugs most associated with it below.

36
reports citing this reaction
8.3%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
36
Total Reports
3
Deaths
8.3%
Death Rate

Species Most Affected

Dog 32
Cat 4

Breeds Most Affected

Chihuahua 6
Domestic Shorthair 3
Boxer (German Boxer) 3
Shepherd Dog - German 3
Crossbred Canine/dog 3
Retriever - Labrador 2
Beagle 2
Spitz - German Pomeranian 2
Dog (unknown) 1
Terrier - Jack Russell 1

Associated Drugs

Afoxolaner 8
Milbemycin Oxime + Spinosad 6
Sarolaner 3
Fluralaner 13.64% 12-Week Chew 3
Enrofloxacin 2
Oclacitinib Maleate 2
Prednisone 2
Spinosad 2
Fluralaner Chew Tablets 2
Ivermectin + Pyrantel As Pamoate Salt 2
Pyrantel Pamoate;Sarolaner 2
Rabies Vaccine 2
Marbofloxacin 1
Dexmedetomidine Hydrochloride 1
Cefovecin 1
Atipamezole Hydrochloride 1
Ceftiofur Sodium 1
Fentanyl 1
Hydromorphone 1
Meloxicam 1

Disturbance in attention Reaction Insights

36 reports name Disturbance in attention; 3 recorded a death outcome (8.3% of reported events, not a population-level mortality rate). VeDDRA code: 1420.

By species: Dog (32 reports), Cat (4 reports). By breed: Chihuahua (6), Domestic Shorthair (3), Boxer (German Boxer) (3).

Most co-reported drugs: Afoxolaner (8 reports), Milbemycin Oxime + Spinosad (6 reports), Sarolaner (3 reports), Fluralaner 13.64% 12-Week Chew (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.