Reaction profile

The FDA adverse-event record for erythrocytosis

16 FDA adverse-event reports reference erythrocytosis (VeDDRA 99307). See the species, breeds, and drugs most associated with it below.

16
reports citing this reaction
18.8%
death-coded share
Dog
most-affected species
Imidacloprid + Moxidectin
most-associated drug
Verify with FDA CVM →
16
Total Reports
3
Deaths
18.8%
Death Rate

Species Most Affected

Dog 11
Cat 5

Breeds Most Affected

Domestic Shorthair 4
Pinscher - Miniature 2
Chihuahua 2
Retriever - Labrador 2
Ragdoll 1
Boxer (German Boxer) 1
Terrier - Yorkshire 1
Poodle - Toy 1
Bichon Frise 1
Dog (other) 1

Associated Drugs

Imidacloprid + Moxidectin 2
Melarsomine Dihydrocloride Injectable 25Mg/Ml 2
Emodepside + Praziquantel 2
Fluid Therapy 2
Trilostane 2
Gabapentin 2
Ivermectin/Pyrantel Chew. Dog 272Mcg/227Mg 1
Aminopentamide 1
Melarsomine Dihydrochloride Injection 1
Cyclosporine A 1
Moxidectin 1
Maropitant Citrate 1
Robenacoxib 1
Firocoxib 1
Deracoxib 1
Tramadol 1
Phycocyanin + Glucosamine + Methylsulfonylmethane + Minerals + Essential Fatty Acids 1
Suture 1
Ampicillin Sodium/Sulbactam Sodium 1
Enrofloxacin 1

ERYTHROCYTOSIS Reaction Insights

16 reports name ERYTHROCYTOSIS; 3 recorded a death outcome (18.8% of reported events, not a population-level mortality rate). VeDDRA code: 99307.

By species: Dog (11 reports), Cat (5 reports). By breed: Domestic Shorthair (4), Pinscher - Miniature (2), Chihuahua (2).

Most co-reported drugs: Imidacloprid + Moxidectin (2 reports), Melarsomine Dihydrocloride Injectable 25Mg/Ml (2 reports), Emodepside + Praziquantel (2 reports), Fluid Therapy (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.