Reaction profile

The FDA adverse-event record for leucopenia nos

2,998 FDA reports name leucopenia nos, a high-volume reaction in the CVM extract (VeDDRA 164). Plate stamps and neighbourhood peers follow.

#158 of 2,481
by report volume (all reactions)
2,998
reports citing this reaction
19.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Leucopenia NOS has 2,998 reports now versus 2,995 in that prior snapshot: 3 more (0.1%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Leucopenia NOS changes

FDA AER · VeDDRA plate

Code 164 VOL-MID

VOL-MID · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,998 reports
  • DEATH-ELEV 19.7%
  • TOP-DECILE #158/2481
  • PHOTO-FINISH Tachypnoea
  • SPECIES-DOG Dog · 2,506
  • DRUG-LEAD Oclacitinib Malea… · 877
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tachypnoea (±13 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Leucopenia NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Seal, Abnormal · near3049Elevated gamma-glutam… · near3047Tachypnoea · near3011Leucopenia NOS · this reacti…2998Hard, clumping · near2964Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Leucopenia NOS

What the FDA AER plate says about Leucopenia NOS

Signature read: 591 death-coded reports is a heavy tail count for Leucopenia NOS in the CVM extract. Report volume is upper-third scale: 2,998 named reports in the openFDA extract. 591 of 2,998 reports were death-coded (19.7% of named reports, not a population mortality rate). Nearest volume peer: Tachypnoea (±13 reports). Lead species Dog (2,506). Lead co-reported drug Oclacitinib Maleate (877).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 2,506
Cat 409
Horse 76
Cattle 2
Human 2
Alpaca 1
Cockatiel 1
Other Birds 1

Breeds Most Affected

Retriever - Labrador 295
Domestic Shorthair 211
Retriever - Golden 152
Crossbred Canine/dog 147
Chihuahua 94
Terrier - Bull - American Pit 83
Terrier - Yorkshire 76
Boxer (German Boxer) 73
Shih Tzu 72
Shepherd Dog - German 62

Associated Drugs

Oclacitinib Maleate 877
Maropitant Citrate 264
Carprofen 261
Moxidectin 144
Prednisone 129
Cefovecin 128
Gabapentin 118
Afoxolaner 107
Ilunocitinib 102
Enrofloxacin 99
Anti-Il31 Mab Mcs Lot #1283563 91
Milbemycin Oxime + Spinosad 89
Cyclosporine 82
Meloxicam 80
Deracoxib 78
Famotidine 78
Metronidazole 78
Toceranib Phosphate 72
Dexamethasone 70
Spinosad 68

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Leucopenia NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,998 here).

Similar death-coded share

Nearest other reactions by death-coded share (19.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Leucopenia NOS (#158 of 2,481 by report volume); death-coded 19.7%. PlainBreed reaction plate · death-coded report count stamp 591 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →