Reaction profile

The FDA adverse-event record for defecation related to convulsion

170 FDA adverse-event reports reference defecation related to convulsion (VeDDRA 2771). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1122 of 2,481
by report volume (all reactions)
170
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Defecation related to convulsion has 170 reports now versus 162 in that prior snapshot: 8 more (4.9%).

Report change
+8
Death-coded reports
+0
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Defecation related to convulsion changes

FDA AER · VeDDRA plate

Code 2771 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 170 reports
  • DEATH-ELEV 10.0%
  • MID-PACK #1122/2481
  • PHOTO-FINISH Depressed reflexes
  • SPECIES-DOG Dog · 161
  • DRUG-LEAD Afoxolaner · 42
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Depressed reflexes (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Defecation related to convulsion

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abrasion · near171Defecation related to… · thi…170Depressed reflexes · near170Dysphagia · near170Administration device… · near169Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Defecation related to convulsion

Signature read: death-coded share at 10.0% is the most distinctive outcome stamp on Defecation related to convulsion. Report volume sits in the middle third of the reaction corpus. 17 of 170 reports were death-coded (10.0% of named reports, not a population mortality rate). Nearest volume peer: Depressed reflexes (±0 reports). Lead species Dog (161). Lead co-reported drug Afoxolaner (42).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 161
Cat 9

Breeds Most Affected

Crossbred Canine/dog 13
Retriever - Labrador 12
Retriever - Golden 12
Chihuahua 8
Shih Tzu 8
Pug 7
Shepherd Dog - German 7
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 6
Boxer (German Boxer) 5
Domestic Shorthair 5

Associated Drugs

Afoxolaner 42
Fluralaner 13.64% 12-Week Chew 32
Ivermectin + Pyrantel As Pamoate Salt 23
Gabapentin 8
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 8
Pimobendan 6
Fluralaner 5.46% 1-Month Chew 6
Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet 6
Milbemycin Oxime + Spinosad 5
Afoxolaner 37.5Mg / Moxidectin 180Mcg / Pyrantel 75Mg Chewable Tablet 5
Doxycycline 5
Afoxolaner 18.75Mg / Moxidectin 90Mcg / Pyrantel 37.5Mg Chewable Tablet 5
Meloxicam 4
Milbemycin/Lufenuron/Pzq Chew 4
Milbemycin Oxime + Praziquantel 4
Phenobarbital 3
Moxidectin 3
Famotidine 3
Fipronil + S-Methoprene 3
Sarolaner 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Defecation related to convulsion, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (170 here).

Similar death-coded share

Nearest other reactions by death-coded share (10.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Defecation related to convulsion (#1122 of 2,481 by report volume); death-coded 10.0%. PlainBreed reaction plate · death-coded share stamp 10.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →