Reaction profile

The FDA adverse-event record for hyperphosphataemia

4,554 FDA reports name hyperphosphataemia, a high-volume reaction in the CVM extract (VeDDRA 2046). Plate stamps and neighbourhood peers follow.

#106 of 2,481
by report volume (all reactions)
4,554
reports citing this reaction
38.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hyperphosphataemia has 4,554 reports now versus 4,468 in that prior snapshot: 86 more (1.9%).

Report change
+86
Death-coded reports
+19
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hyperphosphataemia changes

FDA AER · VeDDRA plate

Code 2046 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 4,554 reports
  • DEATH-HOT 38.1%
  • TOP-DECILE #106/2481
  • PHOTO-FINISH Falling
  • SPECIES-DOG Dog · 3,582
  • DRUG-LEAD Carprofen · 544
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Falling (±16 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Hyperphosphataemia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Urinary tract infecti… · near4609Falling · near4570Hyperphosphataemia · this re…4554Erythema (for urticar… · near4509Nausea · near4502Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hyperphosphataemia

Hyperphosphataemia: high death-coded share in the FDA AER plate

Signature read: 1,736 death-coded reports is a heavy tail count for Hyperphosphataemia in the CVM extract. Report volume is upper-third scale: 4,554 named reports in the openFDA extract. Death-coded share is upper-third: 1,736 of 4,554 reports (38.1% of named reports). Nearest volume peer: Falling (±16 reports). Lead species Dog (3,582). Lead co-reported drug Carprofen (544).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 3,582
Cat 952
Horse 9
Cattle 6
Pig 1
Lion 1
Tiger 1
Wolf 1
Monkey 1

Breeds Most Affected

Domestic Shorthair 498
Retriever - Labrador 430
Crossbred Canine/dog 247
Chihuahua 161
Terrier - Yorkshire 157
Domestic (unspecified) 148
Boxer (German Boxer) 136
Retriever - Golden 135
Shepherd Dog - German 115
Maltese 94

Associated Drugs

Carprofen 544
Maropitant Citrate 496
Trilostane 465
Meloxicam 445
Milbemycin Oxime + Spinosad 258
Afoxolaner 221
Deracoxib 201
Bedinvetmab 198
Gabapentin 187
Cefovecin 176
Oclacitinib Maleate 152
Fluralaner Chew Tablets 152
Famotidine 147
Spinosad 139
Moxidectin 138
Firocoxib 128
Tramadol 128
Prednisone 124
Buprenorphine 124
Robenacoxib 119

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hyperphosphataemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (4,554 here).

Similar death-coded share

Nearest other reactions by death-coded share (38.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hyperphosphataemia (#106 of 2,481 by report volume); death-coded 38.1%. PlainBreed reaction plate · death-coded report count stamp 1,736 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →