Reaction profile

The FDA adverse-event record for hyperphosphataemia

4,346 FDA adverse-event reports reference hyperphosphataemia (VeDDRA 2046). See the species, breeds, and drugs most associated with it below.

4,346
reports citing this reaction
38.4%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
4,346
Total Reports
1,668
Deaths
38.4%
Death Rate

Species Most Affected

Dog 3,457
Cat 872
Horse 7
Cattle 5
Pig 1
Tiger 1
Lion 1
Wolf 1
Monkey 1

Breeds Most Affected

Domestic Shorthair 444
Retriever - Labrador 421
Crossbred Canine/dog 242
Chihuahua 154
Domestic (unspecified) 148
Terrier - Yorkshire 147
Boxer (German Boxer) 133
Retriever - Golden 129
Shepherd Dog - German 113
Maltese 93

Associated Drugs

Carprofen 534
Maropitant Citrate 468
Trilostane 452
Meloxicam 436
Milbemycin Oxime + Spinosad 257
Afoxolaner 220
Deracoxib 200
Bedinvetmab 178
Cefovecin 172
Gabapentin 167
Fluralaner Chew Tablets 152
Famotidine 141
Spinosad 139
Oclacitinib Maleate 139
Moxidectin 131
Tramadol 128
Firocoxib 125
Buprenorphine 117
Prednisone 114
Robenacoxib 111

Hyperphosphataemia Reaction Insights

4,346 reports name Hyperphosphataemia; 1,668 recorded a death outcome (38.4% of reported events, not a population-level mortality rate). VeDDRA code: 2046.

By species: Dog (3,457 reports), Cat (872 reports), Horse (7 reports). By breed: Domestic Shorthair (444), Retriever - Labrador (421), Crossbred Canine/dog (242).

Most co-reported drugs: Carprofen (534 reports), Maropitant Citrate (468 reports), Trilostane (452 reports), Meloxicam (436 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.