Bumping into walls

Verify with FDA CVM →

VeDDRA Code: 2403

472 adverse event reports referencing this reaction

472
Total Reports
96
Deaths
2030.0%
Death Rate

Species Most Affected

Dog 386
Cat 81
Horse 3
Donkey 1
Unknown 1

Breeds Most Affected

Retriever - Labrador 45
Domestic Shorthair 41
Crossbred Canine/dog 27
Shih Tzu 19
Chihuahua 19
Retriever - Golden 16
Shepherd Dog - German 14
Terrier (unspecified) 14
Domestic Mediumhair 14
Dog (unknown) 13

Associated Drugs

Afoxolaner 55
Bedinvetmab 45
Pyrantel Pamoate;Sarolaner 38
Fluralaner 13.64% 12-Week Chew 34
Fluralaner Chew Tablets 27
Ivermectin + Pyrantel As Pamoate Salt 24
Trilostane 23
Carprofen 19
Sarolaner 19
Oclacitinib Maleate 17
Maropitant Citrate 16
Enrofloxacin 13
Milbemycin Oxime + Spinosad 13
Ivermectin 12
Fluralaner Spot-On Solution 12
Gabapentin 12
Moxidectin 12
Buprenorphine 11
Lotilaner 10
Frunevetmab 10

Data Summary

Metric Value
Total reports referencing reaction 472
Reports with fatal outcome 96
Case-fatality rate (reported events) 2030.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2403.

Bumping into walls Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 472 adverse event reports that reference Bumping into walls as a reaction term, including 96 reports with a death outcome — a 2030.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2403, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Bumping into walls appears most frequently in reports for Dog (386 reports), Cat (81 reports), Horse (3 reports) — with Dog dominating at 386 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (45), Domestic Shorthair (41), Crossbred Canine/dog (27). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Bumping into walls are Afoxolaner (55 reports), Bedinvetmab (45 reports), Pyrantel Pamoate;Sarolaner (38 reports), Fluralaner 13.64% 12-Week Chew (34 reports), with Afoxolaner appearing alongside this reaction in 55 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial