Reaction profile

The FDA adverse-event record for boil

Name: Boil - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

23 FDA reports name boil, a lower-volume reaction in the CVM extract (VeDDRA 1355). Plate stamps and neighbourhood peers follow.

#2103 of 2,481
by report volume (all reactions): 23
reports citing this reaction: 4.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Boil has 23 reports now versus 23 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Boil changes

FDA AER · VeDDRA plate

Code 1355 VOL-TRACE

VOL-TRACE · DEATH-LOW · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 23 reports
DEATH-LOW 4.3%
LOWER-Q #2103/2481
PHOTO-FINISH Anal oedema
SPECIES-DOG Dog · 21
DRUG-LEAD Afoxolaner · 6
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anal oedema (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Boil

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Boil

Boil: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Boil in the CVM extract. Report volume is lower-third scale: 23 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 23 reports (4.3% of named reports). Nearest volume peer: Anal oedema (±0 reports). Lead species Dog (21). Lead co-reported drug Afoxolaner (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 21

Cat 1

Human 1

Breeds Most Affected

Beagle 2

Crossbred Canine/dog 2

Shepherd Dog - German 2

Terrier - Yorkshire 1

Pug 1

Poodle - Miniature 1

Shih Tzu 1

Chihuahua 1

Maltese 1

Collie - Border 1

Associated Drugs

Afoxolaner 6

Ivermectin + Pyrantel As Pamoate Salt 3

Oclacitinib Maleate 2

Carprofen 2

Selamectin 2

Moxidectin 2

Ilunocitinib 2

Glucosamine + Chondroitin 2

Neomycin Sulfate, Isoflupredone Acetate And Tetracaine Hydrochloride 2

Ivermectin 68Mcg Pyrantel 57Mg 1

Maropitant Citrate 1

Cefovecin 1

Fluralaner Chew Tablets 1

Milbemycin Oxime + Praziquantel 1

Imidacloprid + Moxidectin 1

Enrofloxacin 1

Flumethrin-Imidacloprid 1

Sodium Bicarbonate (Baking Soda) 1

Ascorbic Acid- Vitamin C 1

Herbal Bladder Formula 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Boil (#2103 of 2,481 by report volume); death-coded 4.3%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →