Reaction profile

The FDA adverse-event record for contamination nos

519 FDA reports name contamination nos, a high-volume reaction in the CVM extract (VeDDRA 99008). Plate stamps and neighbourhood peers follow.

#634 of 2,481
by report volume (all reactions)
519
reports citing this reaction
1.3%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Contamination NOS has 519 reports now versus 507 in that prior snapshot: 12 more (2.4%).

Report change
+12
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Contamination NOS changes

FDA AER · VeDDRA plate

Code 99008 VOL-MID

VOL-MID · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 519 reports
  • DEATH-LOW 1.3%
  • MID-PACK #634/2481
  • PHOTO-FINISH Bumping into walls
  • SPECIES-UNKNOWN Unknown · 487
  • DRUG-LEAD Ivermectin, Pyran… · 79
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bumping into walls (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Contamination NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hypocortisolaemia · near521Papilloma · near521Contamination NOS · this rea…519Bumping into walls · near518Muscle atrophy (see a… · near516Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Contamination NOS

Contamination NOS: low death-coded share in the FDA AER plate

Signature read: Contamination NOS's 1.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 519 named reports in the openFDA extract. Death-coded share is lower-third: 7 of 519 reports (1.3% of named reports). Nearest volume peer: Bumping into walls (±1 reports). Lead species Unknown (487). Lead co-reported drug Ivermectin, Pyrantel (79).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin, Pyrantel appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 487
Dog 20
Cattle 4
Cat 4
Horse 2
Human 1
Rat 1

Breeds Most Affected

Unknown 489
Dog (unknown) 5
Retriever - Labrador 4
Holstein-Friesian also known as Holstein 2
Cat (unknown) 2
Crossbred Canine/dog 2
Domestic Shorthair 2
Mixed (Horse) 1
Shih Tzu 1
Cattle (other) 1

Associated Drugs

Ivermectin, Pyrantel 79
Enrofloxacin 43
Oxytetracycline Dihydrate 34
Moxidectin 23
Ivermectin + Pyrantel As Pamoate Salt 19
Flunixin Meglumine 17
Carprofen 15
Clorsulon + Ivermectin 13
Ivermectin 12
Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride 12
Flunixin Meglumine Injectable 12
Ivermectin + Praziquantel + Pyrantel Pamoate 12
Furosemide 10
Ceftiofur Sodium 9
Milbemycin 9
Insulin Injectable Vial 9
Cefovecin 9
Ivermectin + Pyrantel 8
Maropitant Citrate 7
Fluralaner 13.64% 12-Week Chew 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Contamination NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (519 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Contamination NOS (#634 of 2,481 by report volume); death-coded 1.3%. PlainBreed reaction plate · death-coded share stamp 1.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →