Reaction profile

The FDA adverse-event record for bloody diarrhoea

10,014 FDA reports name bloody diarrhoea, a high-volume reaction in the CVM extract (VeDDRA 315). Plate stamps and neighbourhood peers follow.

#47 of 2,481
by report volume (all reactions)
10,014
reports citing this reaction
10.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bloody diarrhoea has 10,014 reports now versus 9,875 in that prior snapshot: 139 more (1.4%).

Report change
+139
Death-coded reports
+9
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bloody diarrhoea changes

FDA AER · VeDDRA plate

Code 315 VOL-HIGH

VOL-HIGH · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 10,014 reports
  • DEATH-ELEV 10.8%
  • TOP-DECILE #47/2481
  • PHOTO-FINISH Elevated blood urea n…
  • SPECIES-DOG Dog · 9,524
  • DRUG-LEAD Carprofen · 853
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Elevated blood urea nitrogen (BUN) (±153 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Bloody diarrhoea

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Product problem · near10340Uncoded sign · near10179Elevated blood urea n… · near10167Bloody diarrhoea · this reac…10014Polydipsia · near9574Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Bloody diarrhoea

What the FDA AER plate says about Bloody diarrhoea

Signature read: 10,014 reports place Bloody diarrhoea in the upper third of FDA AER volume (#47 of 2,481). Report volume is upper-third scale: 10,014 named reports in the openFDA extract. 1,083 of 10,014 reports were death-coded (10.8% of named reports, not a population mortality rate). Nearest volume peer: Elevated blood urea nitrogen (BUN) (±153 reports). Lead species Dog (9,524). Lead co-reported drug Carprofen (853).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 9,524
Cat 380
Cattle 86
Chicken 5
Horse 5
Human 3
Pig 3
Ferret 2
Turkey 1
Goat 1

Breeds Most Affected

Retriever - Labrador 806
Crossbred Canine/dog 799
Terrier - Yorkshire 535
Chihuahua 444
Retriever - Golden 370
Dog (unknown) 307
Shih Tzu 297
Shepherd Dog - German 280
Beagle 234
Maltese 209

Associated Drugs

Carprofen 853
Milbemycin Oxime + Spinosad 814
Moxidectin 766
Afoxolaner 631
Maropitant Citrate 593
Ivermectin + Pyrantel As Pamoate Salt 529
Fluralaner Chew Tablets 471
Pyrantel Pamoate;Sarolaner 424
Grapiprant 396
Milbemycin Oxime + Praziquantel 317
Oclacitinib Maleate 312
Metronidazole 300
Spinosad 270
Trilostane 264
Meloxicam 258
Gabapentin 250
Melarsomine Dihydrochloride 224
Fluralaner 13.64% 12-Week Chew 219
Bedinvetmab 216
Prednisone 200

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Bloody diarrhoea, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (10,014 here).

Similar death-coded share

Nearest other reactions by death-coded share (10.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bloody diarrhoea (#47 of 2,481 by report volume); death-coded 10.8%. PlainBreed reaction plate · report volume stamp 10,014 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →