Reaction profile

The FDA adverse-event record for strabismus

163 FDA adverse-event reports reference strabismus (VeDDRA 1895). See the species, breeds, and drugs most associated with it below.

163
reports citing this reaction
27.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
163
Total Reports
44
Deaths
27.0%
Death Rate

Species Most Affected

Dog 149
Cat 9
Horse 2
Human 1
Goat 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 13
Chihuahua 12
Crossbred Canine/dog 10
Retriever - Golden 8
Shepherd Dog - German 7
Terrier - Yorkshire 7
Shepherd Dog - Australian 6
Beagle 5
Boxer (German Boxer) 4
Pit Bull 4

Associated Drugs

Milbemycin Oxime + Spinosad 28
Spinosad 17
Carprofen 13
Maropitant Citrate 13
Pyrantel Pamoate;Sarolaner 11
Fluralaner Chew Tablets 9
Fluralaner 13.64% 12-Week Chew 9
Afoxolaner 8
Gabapentin 7
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 6
Bedinvetmab 6
Moxidectin 5
Dexamethasone 5
Isoflurane 4
Prednisone 4
Nitenpyram 4
Ivermectin + Pyrantel As Pamoate Salt 4
Ivermectin 3
Penicillin 3
Milbemycin Oxime 3

Strabismus Reaction Insights

163 reports name Strabismus; 44 recorded a death outcome (27.0% of reported events, not a population-level mortality rate). VeDDRA code: 1895.

By species: Dog (149 reports), Cat (9 reports), Horse (2 reports). By breed: Retriever - Labrador (13), Chihuahua (12), Crossbred Canine/dog (10).

Most co-reported drugs: Milbemycin Oxime + Spinosad (28 reports), Spinosad (17 reports), Carprofen (13 reports), Maropitant Citrate (13 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.