Reaction profile

The FDA adverse-event record for proprioception loss

350 FDA adverse-event reports reference proprioception loss (VeDDRA 1158). See the species, breeds, and drugs most associated with it below.

350
reports citing this reaction
28.6%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
350
Total Reports
100
Deaths
28.6%
Death Rate

Species Most Affected

Dog 326
Cat 23
Cattle 1

Breeds Most Affected

Retriever - Labrador 43
Crossbred Canine/dog 23
Shepherd Dog - German 20
Domestic Shorthair 19
Chihuahua 15
Retriever - Golden 14
Shepherd Dog - Australian 13
Boxer (German Boxer) 12
Terrier - Yorkshire 10
Terrier (unspecified) 9

Associated Drugs

Bedinvetmab 129
Gabapentin 56
Carprofen 52
Prednisone 23
Afoxolaner 20
Milbemycin Oxime + Spinosad 16
Melarsomine Dihydrochloride Injection 16
Galliprant 16
Meloxicam 15
Moxidectin 13
Maropitant Citrate 12
Sarolaner 12
Grapiprant 12
Tramadol 11
Pyrantel Pamoate;Sarolaner 11
Frunevetmab 10
Ivermectin + Pyrantel As Pamoate Salt 9
Trilostane 9
Methocarbamol 8
Oclacitinib Maleate 8

Proprioception loss Reaction Insights

350 reports name Proprioception loss; 100 recorded a death outcome (28.6% of reported events, not a population-level mortality rate). VeDDRA code: 1158.

By species: Dog (326 reports), Cat (23 reports), Cattle (1 reports). By breed: Retriever - Labrador (43), Crossbred Canine/dog (23), Shepherd Dog - German (20).

Most co-reported drugs: Bedinvetmab (129 reports), Gabapentin (56 reports), Carprofen (52 reports), Prednisone (23 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.