Reaction profile

The FDA adverse-event record for proprioception loss

382 FDA reports name proprioception loss, a high-volume reaction in the CVM extract (VeDDRA 1158). Plate stamps and neighbourhood peers follow.

#753 of 2,481
by report volume (all reactions)
382
reports citing this reaction
29.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Proprioception loss has 382 reports now versus 368 in that prior snapshot: 14 more (3.8%).

Report change
+14
Death-coded reports
+5
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Proprioception loss changes

FDA AER · VeDDRA plate

Code 1158 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 382 reports
  • DEATH-HOT 29.8%
  • MID-PACK #753/2481
  • PHOTO-FINISH Hair modification NOS
  • SPECIES-DOG Dog · 347
  • DRUG-LEAD Bedinvetmab · 144
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hair modification NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Proprioception loss

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Disorder of red blood… · near383Hair modification NOS · near382Proprioception loss · this r…382Stroke · near382Alopecia general · near381Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Proprioception loss

Proprioception loss: high death-coded share in the FDA AER plate

Signature read: 114 death-coded reports is a heavy tail count for Proprioception loss in the CVM extract. Report volume is upper-third scale: 382 named reports in the openFDA extract. Death-coded share is upper-third: 114 of 382 reports (29.8% of named reports). Nearest volume peer: Hair modification NOS (±0 reports). Lead species Dog (347). Lead co-reported drug Bedinvetmab (144).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 347
Cat 33
Cattle 1
Horse 1

Breeds Most Affected

Retriever - Labrador 52
Domestic Shorthair 28
Crossbred Canine/dog 24
Shepherd Dog - German 21
Chihuahua 16
Retriever - Golden 15
Shepherd Dog - Australian 13
Boxer (German Boxer) 13
Terrier - Yorkshire 10
Terrier (unspecified) 9

Associated Drugs

Bedinvetmab 144
Gabapentin 62
Carprofen 55
Prednisone 24
Afoxolaner 20
Milbemycin Oxime + Spinosad 16
Melarsomine Dihydrochloride Injection 16
Grapiprant 16
Meloxicam 15
Frunevetmab 15
Galliprant 15
Moxidectin 14
Maropitant Citrate 13
Sarolaner 12
Pyrantel Pamoate;Sarolaner 12
Tramadol 11
Phenobarbital 10
Ivermectin + Pyrantel As Pamoate Salt 9
Cefovecin 9
Oclacitinib Maleate 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Proprioception loss, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (382 here).

Similar death-coded share

Nearest other reactions by death-coded share (29.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Proprioception loss (#753 of 2,481 by report volume); death-coded 29.8%. PlainBreed reaction plate · death-coded report count stamp 114 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →