Reaction profile

The FDA adverse-event record for unsteady gait

1,607 FDA reports name unsteady gait, a high-volume reaction in the CVM extract (VeDDRA 1858). Plate stamps and neighbourhood peers follow.

#271 of 2,481
by report volume (all reactions)
1,607
reports citing this reaction
11.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unsteady gait has 1,607 reports now versus 1,566 in that prior snapshot: 41 more (2.6%).

Report change
+41
Death-coded reports
+8
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unsteady gait changes

FDA AER · VeDDRA plate

Code 1858 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,607 reports
  • DEATH-ELEV 11.8%
  • UPPER-Q #271/2481
  • PHOTO-FINISH Skin sore
  • SPECIES-DOG Dog · 1,316
  • DRUG-LEAD Milbemycin Oxime… · 247
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Skin sore (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Unsteady gait

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Crust · near1615Unsteady gait · this reaction1607Skin sore · near1606Hot spot (pyotraumati… · near1604Hyperproteinaemia · near1597Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Unsteady gait

What the FDA AER plate says about Unsteady gait

Signature read: 1,607 reports place Unsteady gait in the upper third of FDA AER volume (#271 of 2,481). Report volume is upper-third scale: 1,607 named reports in the openFDA extract. 190 of 1,607 reports were death-coded (11.8% of named reports, not a population mortality rate). Nearest volume peer: Skin sore (±1 reports). Lead species Dog (1,316). Lead co-reported drug Milbemycin Oxime + Spinosad (247).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,316
Cat 266
Horse 15
Cattle 4
Donkey 2
Human 2
Other Rodents 1
Llama 1

Breeds Most Affected

Domestic Shorthair 173
Retriever - Labrador 123
Crossbred Canine/dog 83
Retriever - Golden 69
Shepherd Dog - German 65
Chihuahua 60
Shih Tzu 48
Dog (unknown) 44
Terrier - Yorkshire 42
Shepherd Dog - Australian 32

Associated Drugs

Milbemycin Oxime + Spinosad 247
Bedinvetmab 117
Afoxolaner 96
Sarolaner 84
Pyrantel Pamoate;Sarolaner 84
Spinosad 83
Gabapentin 82
Maropitant Citrate 77
Ivermectin + Pyrantel As Pamoate Salt 73
Carprofen 72
Trilostane 60
Fluralaner 13.64% 12-Week Chew 51
Milbemycin Oxime + Praziquantel 50
Moxidectin 42
Fluralaner Chew Tablets 41
Ivermectin 39
Buprenorphine 39
Oclacitinib Maleate 38
Grapiprant 36
Polysulfated Glycosaminoglycan 34

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Unsteady gait, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,607 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unsteady gait (#271 of 2,481 by report volume); death-coded 11.8%. PlainBreed reaction plate · report volume stamp 1,607 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →