Reaction profile

The FDA adverse-event record for bile acids abnormal, blood

31 FDA adverse-event reports reference bile acids abnormal, blood (VeDDRA 99193). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
16.1%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
31
Total Reports
5
Deaths
16.1%
Death Rate

Species Most Affected

Dog 30
Cat 1

Breeds Most Affected

Retriever - Labrador 4
Maltese 3
Crossbred Canine/dog 3
Pit Bull 2
Shepherd Dog - German 2
Boxer (German Boxer) 2
Chihuahua 1
Ridgeback - Rhodesian 1
Terrier - Yorkshire 1
Pinscher - Miniature 1

Associated Drugs

Carprofen 10
Firocoxib 4
Milbemycin 2
Selamectin 2
Masitinib Mesylate 2
Bupivacaine 2
Cyclosporine 1
Spinosad 1
Maropitant 1
Ormetoprim, Sulfadimethoxine 1
Trilostane 1
Cefovecin Sodium 1
Milbemycin, Lufenuron 1
Glycosaminoglycan Polysulfate 1
Lecithin/Liver Powder/Salmon And Flaxseed Meal/Spirulina/Bee Pollen/Kelp/Tang Kwei/Burdock Root/Catnip/Dandelion/Ginger/Horsetail/L-Glutamine/L-Taurine 1
Unspecified Probiotic 1
N-Acetylcarnosine 1
Left Spin Water 1
Insulin 1
Cefpodoxime 1

BILE ACIDS ABNORMAL, BLOOD Reaction Insights

31 reports name BILE ACIDS ABNORMAL, BLOOD; 5 recorded a death outcome (16.1% of reported events, not a population-level mortality rate). VeDDRA code: 99193.

By species: Dog (30 reports), Cat (1 reports). By breed: Retriever - Labrador (4), Maltese (3), Crossbred Canine/dog (3).

Most co-reported drugs: Carprofen (10 reports), Firocoxib (4 reports), Milbemycin (2 reports), Selamectin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.