Reaction profile

The FDA adverse-event record for pneumonitis

46 FDA adverse-event reports reference pneumonitis (VeDDRA 2258). See the species, breeds, and drugs most associated with it below.

46
reports citing this reaction
37.0%
death-coded share
Dog
most-affected species
Melarsomine Dihydrochloride
most-associated drug
Verify with FDA CVM →
46
Total Reports
17
Deaths
37.0%
Death Rate

Species Most Affected

Dog 39
Cattle 4
Cat 2
Horse 1

Breeds Most Affected

Crossbred Canine/dog 6
Retriever - Labrador 5
Terrier - Yorkshire 4
Chihuahua 3
Shepherd Dog - German 3
Beagle 2
Terrier - Boston 2
Crossbred Bovine/Cattle 2
Pug 2
Rottweiler 2

Associated Drugs

Melarsomine Dihydrochloride 9
Ivermectin + Pyrantel As Pamoate Salt 8
Milbemycin Oxime + Praziquantel 4
Doxycycline 4
Melarsomine Dihydrochloride Injection 3
Maropitant Citrate 3
Prednisone 3
Tramadol 3
Imidacloprid + Moxidectin 3
Carprofen 3
Moxidectin 2
Oxfendazole 2
Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus, Mannheimia Haemolytica Toxoid 2
Milbemycin Oxime + Spinosad 2
Cefovecin 2
Spinosad 2
Dexamethasone 2
Gabapentin 2
Butorphanol 2
Milbemycin Oxime 2

Pneumonitis Reaction Insights

46 reports name Pneumonitis; 17 recorded a death outcome (37.0% of reported events, not a population-level mortality rate). VeDDRA code: 2258.

By species: Dog (39 reports), Cattle (4 reports), Cat (2 reports). By breed: Crossbred Canine/dog (6), Retriever - Labrador (5), Terrier - Yorkshire (4).

Most co-reported drugs: Melarsomine Dihydrochloride (9 reports), Ivermectin + Pyrantel As Pamoate Salt (8 reports), Milbemycin Oxime + Praziquantel (4 reports), Doxycycline (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.