Reaction profile

The FDA adverse-event record for pneumonitis

48 FDA reports name pneumonitis, a lower-volume reaction in the CVM extract (VeDDRA 2258). Plate stamps and neighbourhood peers follow.

#1761 of 2,481
by report volume (all reactions)
48
reports citing this reaction
35.4%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pneumonitis has 48 reports now versus 47 in that prior snapshot: 1 more (2.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pneumonitis changes

FDA AER · VeDDRA plate

Code 2258 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 48 reports
  • DEATH-HOT 35.4%
  • MID-PACK #1761/2481
  • PHOTO-FINISH Abnormal echocardiogr…
  • SPECIES-DOG Dog · 40
  • DRUG-LEAD Melarsomine Dihyd… · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal echocardiogram (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Pneumonitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal echocardiogr… · near48Application site absc… · near48Brain damage NOS · near48Brain tumour · near48Pneumonitis · this reaction48Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pneumonitis

Pneumonitis: high death-coded share in the FDA AER plate

Signature read: Pneumonitis's 35.4% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 48 named reports in the openFDA extract. Death-coded share is upper-third: 17 of 48 reports (35.4% of named reports). Nearest volume peer: Abnormal echocardiogram (±0 reports). Lead species Dog (40). Lead co-reported drug Melarsomine Dihydrochloride (9).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 40
Cattle 4
Cat 3
Horse 1

Breeds Most Affected

Crossbred Canine/dog 6
Retriever - Labrador 5
Terrier - Yorkshire 4
Chihuahua 3
Shepherd Dog - German 3
Beagle 2
Terrier - Boston 2
Crossbred Bovine/Cattle 2
Pug 2
Rottweiler 2

Associated Drugs

Melarsomine Dihydrochloride 9
Ivermectin + Pyrantel As Pamoate Salt 8
Milbemycin Oxime + Praziquantel 4
Doxycycline 4
Melarsomine Dihydrochloride Injection 3
Maropitant Citrate 3
Prednisone 3
Tramadol 3
Imidacloprid + Moxidectin 3
Carprofen 3
Oclacitinib Maleate 2
Moxidectin 2
Oxfendazole 2
Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus, Mannheimia Haemolytica Toxoid 2
Milbemycin Oxime + Spinosad 2
Cefovecin 2
Spinosad 2
Dexamethasone 2
Gabapentin 2
Butorphanol 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pneumonitis (#1761 of 2,481 by report volume); death-coded 35.4%. PlainBreed reaction plate · death-coded share stamp 35.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →