PLATELETS, ABNORMAL

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VeDDRA Code: 99305

31 adverse event reports referencing this reaction

31
Total Reports
11
Deaths
3550.0%
Death Rate

Species Most Affected

Dog 29
Cat 2

Breeds Most Affected

Shepherd Dog - German 5
Retriever - Labrador 3
Crossbred Canine/dog 3
Retriever - Golden 2
Terrier - Yorkshire 2
Pug 2
Shepherd Dog - Australian 1
Spaniel - King Charles Cavalier 1
Brittany 1
Rottweiler 1

Associated Drugs

Carprofen 6
Spinosad 6
Milbemycin Oxime + Spinosad 6
Cyclosporine 3
Polysulfated Glycosaminoglycan 3
Glycosaminoglycan Polysulfate 2
Ivermectin + Pyrantel Pamoate 2
Doxycycline 2
Grapiprant 2
Melarsomine Dihydrochloride 1
Pyrantel Pamoate 1
Filgrastim Injection 1
Meloxicam 1
Cefpodoxime Proxetil 1
Moxidectin 1
Anesthetic 1
Gentamicin Sulfate 1
Immune Globulin 1
Ivermectin + Pyrantel As Pamoate Salt 1
Nitenpyram 1

Data Summary

Metric Value
Total reports referencing reaction 31
Reports with fatal outcome 11
Case-fatality rate (reported events) 3550.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99305.

PLATELETS, ABNORMAL Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 31 adverse event reports that reference PLATELETS, ABNORMAL as a reaction term, including 11 reports with a death outcome — a 3550.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99305, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

PLATELETS, ABNORMAL appears most frequently in reports for Dog (29 reports), Cat (2 reports) — with Dog dominating at 29 entries. Within those species, the breeds most often named alongside this reaction are Shepherd Dog - German (5), Retriever - Labrador (3), Crossbred Canine/dog (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with PLATELETS, ABNORMAL are Carprofen (6 reports), Spinosad (6 reports), Milbemycin Oxime + Spinosad (6 reports), Cyclosporine (3 reports), with Carprofen appearing alongside this reaction in 6 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial