Reaction profile

The FDA adverse-event record for platelets, abnormal

31 FDA adverse-event reports reference platelets, abnormal (VeDDRA 99305). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
35.5%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
31
Total Reports
11
Deaths
35.5%
Death Rate

Species Most Affected

Dog 29
Cat 2

Breeds Most Affected

Shepherd Dog - German 5
Retriever - Labrador 3
Crossbred Canine/dog 3
Retriever - Golden 2
Terrier - Yorkshire 2
Pug 2
Shepherd Dog - Australian 1
Spaniel - King Charles Cavalier 1
Brittany 1
Rottweiler 1

Associated Drugs

Carprofen 6
Spinosad 6
Milbemycin Oxime + Spinosad 6
Cyclosporine 3
Polysulfated Glycosaminoglycan 3
Glycosaminoglycan Polysulfate 2
Ivermectin + Pyrantel Pamoate 2
Doxycycline 2
Grapiprant 2
Melarsomine Dihydrochloride 1
Pyrantel Pamoate 1
Filgrastim Injection 1
Meloxicam 1
Cefpodoxime Proxetil 1
Moxidectin 1
Anesthetic 1
Gentamicin Sulfate 1
Immune Globulin 1
Ivermectin + Pyrantel As Pamoate Salt 1
Nitenpyram 1

PLATELETS, ABNORMAL Reaction Insights

31 reports name PLATELETS, ABNORMAL; 11 recorded a death outcome (35.5% of reported events, not a population-level mortality rate). VeDDRA code: 99305.

By species: Dog (29 reports), Cat (2 reports). By breed: Shepherd Dog - German (5), Retriever - Labrador (3), Crossbred Canine/dog (3).

Most co-reported drugs: Carprofen (6 reports), Spinosad (6 reports), Milbemycin Oxime + Spinosad (6 reports), Cyclosporine (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.