Reaction profile

The FDA adverse-event record for application site stickiness

471 FDA adverse-event reports reference application site stickiness (VeDDRA 2750). See the species, breeds, and drugs most associated with it below.

471
reports citing this reaction
0.0%
death-coded share
Human
most-affected species
Fluralaner Spot-On Solution
most-associated drug
Verify with FDA CVM →
471
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Human 406
Cat 59
Dog 6

Breeds Most Affected

Unknown 407
Domestic Shorthair 33
Cat (unknown) 10
Domestic Longhair 8
Domestic Mediumhair 3
Chihuahua 2
Maine Coon 1
Bulldog - American 1
Russian 1
Poodle - Miniature 1

Associated Drugs

Fluralaner Spot-On Solution 329
Fluralaner/Moxidectin Spot-On 133
Emodepside + Praziquantel 2
Chlorhexidine + Ophytrium 2
Prednisolone 1
Lactated Ringers Solution 1
Mirtazapine Transdermal Ointment 1
Glucosamine, Chondroitin Sulfate, Avocado/Soybean Unsaponifiables (Asu), Boswellia Serrata Extract, Green Tea Extract, Manganese 1
Genta/Momet/Clotrim Ear Oint 1
Fluralaner 13.64% 12-Week Chew 1
Imidacloprid + Moxidectin 1
Selamectin 1
Antidepressant 1
Telmisartan 1
Eprinomectin + Esafoxolaner + Praziquantel 1
Afoxolaner 1

Application site stickiness Reaction Insights

471 reports name Application site stickiness; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 2750.

By species: Human (406 reports), Cat (59 reports), Dog (6 reports). By breed: Unknown (407), Domestic Shorthair (33), Cat (unknown) (10).

Most co-reported drugs: Fluralaner Spot-On Solution (329 reports), Fluralaner/Moxidectin Spot-On (133 reports), Emodepside + Praziquantel (2 reports), Chlorhexidine + Ophytrium (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.